Sequence of CP2U1_HUMAN
EC Number:1.14.14.80
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
a long-chain fatty acid + [reduced NADPH-hemoprotein reductase] + O2 = an omega-hydroxy-long-chain fatty acid + [oxidized NADPH-hemoprotein reductase] + H2O
Other sequences found for EC No. 1.14.14.80
General information:
Sequence
0 MSSPGPSQPP AEDPPWPARL LRAPLGLLRL DPSGGALLLC GLVALLGWSW LRRRRARGIP
60 PGPTPWPLVG NFGHVLLPPF LRRRSWLSSR TRAAGIDPSV IGPQVLLAHL ARVYGSIFSF
120 FIGHYLVVVL SDFHSVREAL VQQAEVFSDR PRVPLISIVT KEKGVVFAHY GPVWRQQRKF
180 SHSTLRHFGL GKLSLEPKII EEFKYVKAEM QKHGEDPFCP FSIISNAVSN IICSLCFGQR
240 FDYTNSEFKK MLGFMSRGLE ICLNSQVLLV NICPWLYYLP FGPFKELRQI EKDITSFLKK
300 IIKDHQESLD RENPQDFIDM YLLHMEEERK NNSNSSFDEE YLFYIIGDLF IAGTDTTTNS
360 LLWCLLYMSL NPDVQEKVHE EIERVIGANR APSLTDKAQM PYTEATIMEV QRLTVVVPLA
420 IPHMTSENTV LQGYTIPKGT LILPNLWSVH RDPAIWEKPE DFYPNRFLDD QGQLIKKETF
480 IPFGIGKRVC MGEQLAKMEL FLMFVSLMQS FAFALPEDSK KPLLTGRFGL TLAPHPFNIT
540 ISRR
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
147630
Chuang S.S.,Helvig C.,Taimi M.,Ramshaw H.A.,Collop A.H.,Amad M.,White J.A.,Petkovich M.,Jones G.,Korczak B.
CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes omega- and (omega-1)-hydroxylation of fatty acids.
J. Biol. Chem.
279
6305-6314
2004
147632
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
147633
Karlgren M.,Backlund M.,Johansson I.,Oscarson M.,Ingelman-Sundberg M.
Characterization and tissue distribution of a novel human cytochrome P450-CYP2U1.
Biochem. Biophys. Res. Commun.
315
679-685
2004
147634
Choudhary D.,Jansson I.,Stoilov I.,Sarfarazi M.,Schenkman J.B.
Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues.
Arch. Biochem. Biophys.
436
50-61
2005
147635
Siller M.,Goyal S.,Yoshimoto F.K.,Xiao Y.,Wei S.,Guengerich F.P.
Oxidation of endogenous N-arachidonoylserotonin by human cytochrome P450 2U1.
J. Biol. Chem.
289
10476-10487
2014
147636
Tesson C.,Nawara M.,Salih M.A.,Rossignol R.,Zaki M.S.,Al Balwi M.,Schule R.,Mignot C.,Obre E.,Bouhouche A.,Santorelli F.M.,Durand C.M.,Oteyza A.C.,El-Hachimi K.H.,Al Drees A.,Bouslam N.,Lamari F.,Elmalik S.A.,Kabiraj M.M.,Seidahmed M.Z.,Esteves T.,Gaussen M.,Monin M.L.,Gyapay G.,Lechner D.,Gonzalez M.,Depienne C.,Mochel F.,Lavie J.,Schols L.,Lacombe D.,Yahyaoui M.,Al Abdulkareem I.,Zuchner S.,Yamashita A.,Benomar A.,Goizet C.,Durr A.,Gleeson J.G.,Darios F.,Brice A.,Stevanin G.
Alteration of fatty-acid-metabolizing enzymes affects mitochondrial form and function in hereditary spastic paraplegia.
Am. J. Hum. Genet.
91
1051-1064
2012
