Sequence of C9MT_KOMPG
EC Number:2.1.1.317
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
sphingolipid C9-methyltransferase
C4R7Z3
Komagataella phaffii (strain GS115 / ATCC 20864)
489
56272
Reaction
S-adenosyl-L-methionine + a (4E,8E)-sphinga-4,8-dienine ceramide = S-adenosyl-L-homocysteine + a 9-methyl-(4E,8E)-sphinga-4,8-dienine ceramide
Other sequences found for EC No. 2.1.1.317
General information:
Sequence
0 MSQTESTKGV KITNYAAIKN APLPADGPGA KNFSNWLLLG LLTGVPLFVT RKFHGGLKTF
60 IFFFILFAIP ILMAYWTVLS SYSPRLNEKV QFPNRGVEHY LKFHDDQLAA RYQGQNKIPM
120 ETFHELYFEG KVSFKGDALD ALEYRHDWAS FRFTLSLFRF FLLGMIPEVI MHSRSQDEEQ
180 VRDHYDRGDD FYSWFLGDRM VYTSGLISDV NKDESLEELQ DNKLKTVCEK IQLKEGEYLL
240 DLGCGWGTLA AFASSQYGAK VTGITLGKNQ TKYGNDKIAS FGVDEKQSRI LCHDYRDTPL
300 PKDENGNTTK YDKITCLEMA EHVGVRKFRS FLQQVYDMLD DDGVFFLQYA GLRKSWQYED
360 LIWGLFMNKY IFPGADASTP LDFVVSALEA TGFETVSIDN IGVHYSATLY RWYKNWLSNR
420 DNVVNKYGIK WFKIWEYFLA SSTIISRQGS ATCYQIVLRK NLNSYDRAGY ISTQEGLQGP
480 ISRKTDWVK
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
12415
Ternes P.,Sperling P.,Albrecht S.,Franke S.,Cregg J.M.,Warnecke D.,Heinz E.
Identification of fungal sphingolipid C9-methyltransferases by phylogenetic profiling.
J. Biol. Chem.
281
5582-5592
2006
12416
De Schutter K.,Lin Y.-C.,Tiels P.,Van Hecke A.,Glinka S.,Weber-Lehmann J.,Rouze P.,Van de Peer Y.,Callewaert N.
Genome sequence of the recombinant protein production host Pichia pastoris.
Nat. Biotechnol.
27
561-566
2009
12417
Ramamoorthy V.,Cahoon E.B.,Thokala M.,Kaur J.,Li J.,Shah D.M.
Sphingolipid C-9 methyltransferases are important for growth and virulence but not for sensitivity to antifungal plant defensins in Fusarium graminearum.
Eukaryot. Cell
8
217-229
2009
