Sequence of B8MKY6_TALSN
EC Number:2.3.1.161
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
lovastatin nonaketide synthase
B8MKY6
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2570
280373
Reaction
9 malonyl-CoA + 11 NADPH + 10 H+ + S-adenosyl-L-methionine + holo-[lovastatin nonaketide synthase] = dihydromonacolin L-[lovastatin nonaketide synthase] + 9 CoA + 9 CO2 + 11 NADP+ + S-adenosyl-L-homocysteine + 6 H2O
Other sequences found for EC No. 2.3.1.161
General information:
Sequence
0 MSPLIHDDQP YSWNAAMPIA VVGIGFRGPG DATNVENLFR MIAEGRESRI DIPKEKWNHE
60 AFYHPDPSRF GTHNVTGGHY FQQDVSRFDA PFFNMTAAEA AALDPQQRML LECTYEAMEN
120 SGTKMHDFVG SNTSVFVGSF CADYADVLWR DPETVPMYQC TNAGHSRANT ANRVSYIYDL
180 KGPSVTVDTA CSASLVALHL GCQSLRTGDA KQALVAGCSA ILSHEGMVTM SMMRLLSPEG
240 RCYTFDERAG GYARGDGVGA ILLKPLQDAL DAGDTIRAVI RGTGSNQDGK TPGITMPSGT
300 AQEALVRSVY EKIGLDPLDT SYVECHGTGT QAGDVTETSA LARVFEPGRP KDEPLVIGSV
360 KTNIGHLEGA SGVAGVIKTI LMLENGLILP NRNFQKGNPK ILFDEWKLRV PLGVENWEIS
420 KPRRASVNSF GYGGANAHVV LENAQDYLRN HNWEFRSHTR KSATESSGTS TPSNPGPHGR
480 LFVFSSFDEA TGKKYLQSFE KYIEDRLQIA DSEEFLDDLA YTLGERRTNH TWRTAVPAQS
540 AEELLSNLRE GINLGNASQT KNRKIGFVFT GQGAQWCGMG KELIDQYPVF KETIEKAGIA
600 CQKAGATFDL ETELRKDPKE SAINRAIYSQ PLSTAVQLGL IDLLASWGVK PTSVTGHSSG
660 EIASAYAAGA LSLEDAMLVS YSRGVVSSKM AERATVPGCM MAIGMSKEEV LPIVSTLTKG
720 KVVVACSNSP SSVTASGDLP AIDELHTVLD EKGVFNRKLV VEVAYHSHHM ELVKEEYRNA
780 ISSIKVQPGN DVEFFSSVTG ERASISGLGP DYWVSNMIGE VKFNDSLGRL CLETEGPSAT
840 TKKSAQRRKA KVSPVSTLIE IGPHSALAGP IKQIIQANET LNKASIKYYS ALVRNKNAAT
900 TVLNLVGQLF VAGHEPSLEK VNRPTGLESH SVLIDLPPYA WNHANSYWAE SRISKFYRER
960 RFPRTDLLGV LERNSSSIEP RWRNHIRLSE IPWVRDHKIQ GNIVYPAAGY LAMAIEAACQ
1020 HAITVKSIPT ITGYKLREVV IDSALIIPEN PGEVEVAITL KSFTDSIRNP SDMWDEFVIS
1080 SVNADSRWTE HCRGLVSVVA PQKVVNVIDG QAQSIAEKQG YAELVASYET KCRRNINVPQ
1140 FYEQLIELGL EYGPTFANLK RAKAAPNACI GDLEIPDTAA VMPYNFQFPF VIHPATLDAL
1200 FHTIFAALAT ANGGTLKDPA VPVSASEIFV SANITSKPGD KLATYTSTEQ KDYRFMSASM
1260 TVFHESQKQQ GAFEPVIEIK DLTCATLARE GADPSTDGQV TKAYNLAWKP SIDLLSQSEI
1320 LELCAKTSSP EGNTNATNAR ELLERAAYYM LKRAVAGYAP PETNSAYAQQ LWSFLKSQSR
1380 VASWKHAYDG WDQLFKADVD AFIDKVVSSS SVGKFLVEVG DKLPNLVKGE NSSAEFIKEL
1440 DLKVFVDNTQ LFQNTQSAAR YFDLLQHKTP SLSVLAVGPG SGVASLGFLA LLNKKSSAPF
1500 ERYEHNDVEF DIRDVVKEKF PQWAQLIGTK QVDISREIQG QEDIEPNSYD VLVAFHVLGD
1560 ATGMNNVLAQ SKQLLKPDGK VLFIGRPLKS LVASVLFGYV PSVLAETGST SDRSNLSPAE
1620 IDDMVSASGY SKVTAIATSI NSNNYSMMVV SASASQDTSA KPQKVHVIAE DESTSQPSLL
1680 AGLKEEGIEV TVSSLSEASP TPDHMCIVLS DLSNKTVLSD PSVQEWEALK KIMLEAKGVL
1740 WVTRGSAVTT SNPNGSMATG LSRTIRSERG DVPVVTLDLD AERTLDDAVS TDIILKVFRK
1800 SFYPAFTASE VEQEYAERKG RLLVPRLIED EELTKTLAIA TEGAKGQLEP LHQPGRPLRM
1860 FVGTPGLLDS IFWTDDDRVE TPLPDDWVEM EVKASGFNFK DVMMAMGQIK VENLGWECSG
1920 ILTKVGPAVT GLAVGDRVVC HASGTFCTNA RVHVDNVRKI PDTMSFEIAA SLPVTYVTAY
1980 HSIYNIARLQ KGETILVHAA TGGLGQAIIE LCQLIGAEIF ATVGTLDKKK FLIDHFHIPE
2040 DHIFFSRDQS FAAGIKRMTR GKGVDAVMNS LAGEGLRLSW ECIAPYGRFV ELGQRDIGIN
2100 SRLEMGQFIK NTSFTAFNLA YMVQYNPKVA NEVFTSVLNL FWKDAIKGPS PVEVYSFSDV
2160 EKAFRRMQTG GHMGKLVGTA DTDAMVKVIP LDRSKSLLRS DASYVLIGGL GGIGRATALW
2220 MVEHGARNVI FVNRSGVKVD EARETIRVLE EMECKTAIFP CDITNENQVE TFVGDAAKAM
2280 PPIKGVIQGA MLLRDTLFEK MSLEDYITVL RPKVQGTFNL HKYLPKDMDF FIMESSVSGI
2340 VGNASQAAYA AGNTFLDAFA SYRVSQGLPA TTIDLGAISG VGYLSTNSEL KQAMERQGFE
2400 FTNPKRLMAL IESAIRNPAR PGQQAHIITG LGTWNEDSSL GALTLPMFSH FRHLSAGNAD
2460 WGKSGSGNNL KSALKAAKTL DDASELILGA LIDKIASRSG IGPENINTSK SMPDYGIDSL
2520 VAVEMRNWIT KDMDSTLPVL ELLASDPLTH LATKIAQRSR SVQVAEQTHE
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
20470938
Nierman W.C.,Fedorova-Abrams N.D.,Andrianopoulos A.
Genome sequence of the AIDS-associated pathogen Penicillium marneffei (ATCC18224) and its near taxonomic relative Talaromyces stipitatus (ATCC10500).
Genome Announc.
3
0-0
2015
