Sequence of ALAT1_HUMAN

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
alanine transaminase
P24298
Homo sapiens
496
54637
Reaction
L-alanine + 2-oxoglutarate = pyruvate + L-glutamate
Sequences with same EC No.
Sequence
  0 MASSTGDRSQ AVRHGLRAKV LTLDGMNPRV RRVEYAVRGP IVQRALELEQ ELRQGVKKPF
 60 TEVIRANIGD AQAMGQRPIT FLRQVLALCV NPDLLSSPNF PDDAKKRAER ILQACGGHSL
120 GAYSVSSGIQ LIREDVARYI ERRDGGIPAD PNNVFLSTGA SDAIVTVLKL LVAGEGHTRT
180 GVLIPIPQYP LYSATLAELG AVQVDYYLDE ERAWALDVAE LHRALGQARD HCRPRALCVI
240 NPGNPTGQVQ TRECIEAVIR FAFEERLFLL ADEVYQDNVY AAGSQFHSFK KVLMEMGPPY
300 AGQQELASFH STSKGYMGEC GFRGGYVEVV NMDAAVQQQM LKLMSVRLCP PVPGQALLDL
360 VVSPPAPTDP SFAQFQAEKQ AVLAELAAKA KLTEQVFNEA PGISCNPVQG AMYSFPRVQL
420 PPRAVERAQE LGLAPDMFFC LRLLEETGIC VVPGSGFGQR EGTYHFRMTI LPPLEKLRLL
480 LEKLSRFHAK FTLEYS
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
131310
Sohocki M.M.,Sullivan L.S.,Harrison W.R.,Sodergren E.J.,Elder F.F.B.,Weinstock G.,Tanase S.,Daiger S.P.
Human glutamate pyruvate transaminase (GPT): localization to 8q24.3, cDNA and genomic sequences, and polymorphic sites.
Genomics
40
247-252
1997
131314
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
131315
Ishiguro M.,Takio K.,Suzuki M.,Oyama R.,Matsuzawa T.,Titani K.
Complete amino acid sequence of human liver cytosolic alanine aminotransferase (GPT) determined by a combination of conventional and mass spectral methods.
Biochemistry
30
10451-10457
1991
131317
Yang R.-Z.,Blaileanu G.,Hansen B.C.,Shuldiner A.R.,Gong D.-W.
cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase.
Genomics
79
445-450
2002
131318
Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
J. Proteomics
96
253-262
2014
131319
Srour M.,Hamdan F.F.,McKnight D.,Davis E.,Mandel H.,Schwartzentruber J.,Martin B.,Patry L.,Nassif C.,Dionne-Laporte A.,Ospina L.H.,Lemyre E.,Massicotte C.,Laframboise R.,Maranda B.,Labuda D.,Decarie J.C.,Rypens F.,Goldsher D.,Fallet-Bianco C.,Soucy J.F.,Laberge A.M.,Maftei C.,Boycott K.,Brais B.,Boucher R.M.,Rouleau G.A.,Katsanis N.,Majewski J.,Elpeleg O.,Kukolich M.K.,Shalev S.,Michaud J.L.
Joubert Syndrome in French Canadians and Identification of Mutations in CEP104.
Am. J. Hum. Genet.
97
744-753
2015