Sequence of MEP1B_RAT
EC Number:3.4.24.63
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Hydrolysis of proteins, including azocasein, and peptides. Hydrolysis of -His5-/-Leu-, -Leu6-/-Cys-, -Ala14-/-Leu- and -Cys19-/-Gly- bonds in insulin B chain
Other sequences found for EC No. 3.4.24.63
General information:
Sequence
0 MDARHWPWFL VFATFLLVSG LPAPEKFVKD IDGGIDQDIF DINEDLGLDL FEGDIKLEAS
60 GRNSIIGDNY RWPHTIPYVL EDSLEMNAKG VILNAFERYR LKTCIDFKPW SGEENYISVF
120 KGSGCWSSVG NIHAGKQELS IGTNCDRIAT VQHEFLHALG FWHEQSRADR DDYITIVWDR
180 ILSGKEHNFN IYNDSVSDSL NVPYDYTSVM HYSKTAFQNG TESTIITKIS DFEDVIGQRM
240 DFSDYDLLKL NQLYSCTSSL SFMDSCDFEL ENICGMIQSS QDSADWQRLS QVLSGPENDH
300 SNMGQCKDSG FFMHFNTSTG NGGVTAMLES RVLYPKRGFQ CVEFYLYNSG SGNGQLNVYT
360 REYTAGHQDG VLTLQREIRD IPTGSWQLYY VTLQVTEKFR VVFEGVGGPG ASSGGLSIDD
420 INLSETRCPH HIWHIQNFTQ LLGGQTTVYS PPFYSSKGYA FQINLDLTSP TNVGLYFHLI
480 SGANDDQLQW PCPWQQATMT LLDQNPDIRQ RMSNQRSITT DPKMTDDNGS YLWDRPSKVG
540 VEAFFPNGTQ FSRGRGYGTS VFITQERLKS REFLKGDDVY ILLTVEDISH LNSTAAVPGP
600 VPTTSTVHNA CSEVECQNGG ICTLQEGRAE CKCPAGEDWW YMGKRCEKRG STKDTIVIAV
660 SSTVTVFAVM LIITLISVYC TRRKYRKKAS AKTAAMNLEN QHAF
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1212662
Johnson G.D.,Hersh L.B.
Cloning a rat meprin cDNA reveals the enzyme is a heterodimer.
J. Biol. Chem.
267
13505-13512
1992
1212665
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
1212666
Chevallier S.,Ahn J.,Boileau G.,Crine P.
Identification of the cysteine residues implicated in the formation of alpha 2 and alpha/beta dimers of rat meprin.
Biochem. J.
317
731-738
1996
1212667
Ishmael F.T.,Shier V.K.,Ishmael S.S.,Bond J.S.
Intersubunit and domain interactions of the meprin B metalloproteinase. Disulfide bonds and protein-protein interactions in the MAM and TRAF domains.
J. Biol. Chem.
280
13895-13901
2005
