Sequence of MASP2_HUMAN

mannan-binding lectin-associated serine protease-2

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A second serine protease associated with mannan-binding lectin that activates complement.

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1210963

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A truncated form of mannose-binding lectin-associated serine protease (MASP)-2 expressed by alternative polyadenylation is a component of the lectin complement pathway.

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1210964

Stover C.M.,Thiel S.,Thelen M.,Lynch N.J.,Vorup-Jensen T.,Jensenius J.C.,Schwaeble W.J.

Two constituents of the initiation complex of the mannan-binding lectin activation pathway of complement are encoded by a single structural gene.

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1210968

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The DNA sequence and biological annotation of human chromosome 1.

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1210970

Rasmussen H.H.,Orntoft T.F.,Wolf H.,Celis J.E.

Towards a comprehensive database of proteins from the urine of patients with bladder cancer.

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1210971

Stover C.,Endo Y.,Takahashi M.,Lynch N.,Constantinescu C.,Vorup-Jensen T.,Thiel S.,Friedl H.,Hankeln T.,Hall R.,Gregory S.,Fujita T.,Schwaeble W.

The human gene for mannan-binding lectin-associated serine protease-2 (MASP-2), the effector component of the lectin route of complement activation, is part of a tightly linked gene cluster on chromosome 1p36.2-3.

Genes Immun.

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1210972

Matsushita M.,Thiel S.,Jensenius J.C.,Terai I.,Fujita T.

Proteolytic activities of two types of mannose-binding lectin-associated serine protease.

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1210973

Gregory L.A.,Thielens N.M.,Matsushita M.,Sorensen R.,Arlaud G.J.,Fontecilla-Camps J.-C.,Gaboriaud C.

The X-ray structure of human mannan-binding lectin-associated protein 19 (MAp19) and its interaction site with mannan-binding lectin and L-ficolin.

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1210974

Harmat V.,Gal P.,Kardos J.,Szilagyi K.,Ambrus G.,Vegh B.,Naray-Szabo G.,Zavodszky P.

The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions.

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2004

1210975

Gal P.,Harmat V.,Kocsis A.,Bian T.,Barna L.,Ambrus G.,Vegh B.,Balczer J.,Sim R.B.,Naray-Szabo G.,Zavodszky P.

A true autoactivating enzyme. Structural insight into mannose-binding lectin-associated serine protease-2 activations.

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1210976

Stengaard-Pedersen K.,Thiel S.,Gadjeva M.,Moller-Kristensen M.,Sorensen R.,Jensen L.T.,Sjoeholm A.G.,Fugger L.,Jensenius J.C.

Inherited deficiency of mannan-binding lectin-associated serine protease 2.

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349

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2003

1210977

Lozano F.,Suarez B.,Munoz A.,Jensenius J.C.,Mensa J.,Vives J.,Horcajada J.P.

Novel MASP2 variants detected among North African and Sub-Saharan individuals.

Tissue Antigens

66

131-135

2005

1210978

Thiel S.,Steffensen R.,Christensen I.J.,Ip W.K.,Lau Y.L.,Reason I.J.,Eiberg H.,Gadjeva M.,Ruseva M.,Jensenius J.C.

Deficiency of mannan-binding lectin associated serine protease-2 due to missense polymorphisms.

Genes Immun.

8

154-163

2007

1210979

Srour M.,Hamdan F.F.,Gan-Or Z.,Labuda D.,Nassif C.,Oskoui M.,Gana-Weisz M.,Orr-Urtreger A.,Rouleau G.A.,Michaud J.L.

A homozygous mutation in SLC1A4 in siblings with severe intellectual disability and microcephaly.

Clin. Genet.

88

0-0

2015