Sequence of TGM5_HUMAN
EC Number:2.3.2.13
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
protein glutamine + alkylamine = protein N5-alkylglutamine + NH3
Other sequences found for EC No. 2.3.2.13
General information:
Sequence
show sequence in normal format
>O43548|protein-glutamine gamma-glutamyltransferase|EC 2.3.2.13|Homo sapiens|Swiss-Prot
MAQGLEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLYFRNRSFQPGLDNIIFV
VETGPLPDLALGTRAVFSLARHHSPSPWIAWLETNGATSTEVSLCAPPTAAVGRYLLKIH
IDSFQGSVTAYQLGEFILLFNPWCPEDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCP
WNYGQFEDKIIDICLKLLDKSLHFQTDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNG
NWSENYTDGANPAEWTGSVAILKQWNATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVIT
NFDSGHDTDGNLIIDEYYDNTGRILGNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLD
ATPQEMSNGVYCCGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSWLVQGGKEQKLHQDT
SSVGNFISTKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQP
SRPTSLSQDSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLK
VNLSAQSLLHDGSPLSPFWQDTAFITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALG
EEKSSPEKILVNKIITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGS
GLFKKQQKVFLGVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYVDFAL
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
108308
Aeschlimann D.,Koeller M.K.,Allen-Hoffmann B.L.,Mosher D.F.
Isolation of a cDNA encoding a novel member of the transglutaminase gene family from human keratinocytes. Detection and identification of transglutaminase gene products based on reverse transcription-polymerase chain reaction with degenerate primers.
J. Biol. Chem.
273
3452-3460
1998
108309
Grenard P.,Bates M.K.,Aeschlimann D.
Evolution of transglutaminase genes: identification of a transglutaminase gene cluster on human chromosome 15q15. Structure of the gene encoding transglutaminase X and a novel gene family member, transglutaminase Z.
J. Biol. Chem.
276
33066-33078
2001
108310
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
108311
Rufini A.,Vilbois F.,Paradisi A.,Oddi S.,Tartaglione R.,Leta A.,Bagetta G.,Guerrieri P.,Finazzi-Agro' A.,Melino G.,Candi E.
Transglutaminase 5 is acetylated at the N-terminal end.
Amino Acids
26
425-430
2004
108312
Cassidy A.J.,van Steensel M.A.M.,Steijlen P.M.,van Geel M.,van der Velden J.,Morley S.M.,Terrinoni A.,Melino G.,Candi E.,McLean W.H.I.
A homozygous missense mutation in TGM5 abolishes epidermal transglutaminase 5 activity and causes acral peeling skin syndrome.
Am. J. Hum. Genet.
77
909-917
2005