Sequence of CATK_MOUSE
EC Number:3.4.22.38
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Broad proteolytic activity. With small-molecule substrates and inhibitors, the major determinant of specificity is P2, which is preferably Leu, Met > Phe, and not Arg
Other sequences found for EC No. 3.4.22.38
General information:
Sequence
0 MWVFKFLLLP MVSFALSPEE MLDTQWELWK KTHQKQYNSK VDEISRRLIW EKNLKQISAH
60 NLEASLGVHT YELAMNHLGD MTSEEVVQKM TGLRIPPSRS YSNDTLYTPE WEGRVPDSID
120 YRKKGYVTPV KNQGQCGSCW AFSSAGALEG QLKKKTGKLL ALSPQNLVDC VTENYGCGGG
180 YMTTAFQYVQ QNGGIDSEDA YPYVGQDESC MYNATAKAAK CRGYREIPVG NEKALKRAVA
240 RVGPISVSID ASLASFQFYS RGVYYDENCD RDNVNHAVLV VGYGTQKGSK HWIIKNSWGE
300 SWGNKGYALL ARNKNNACGI TNMASFPKM
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1165693
Rantakokko J.A.,Aro H.T.,Savontaus M.,Vuorio E.
Mouse cathepsin K: cDNA cloning and predominant expression of the gene in osteoclasts, and in some hypertrophying chondrocytes during mouse development.
FEBS Lett.
393
307-313
1996
1165694
Rantakokko J.A.,Kiviranta R.,Eerola R.,Aro H.T.,Vuorio E.
Complete genomic structure of the mouse cathepsin K gene (Ctsk) and its localization next to the Arnt gene on mouse chromosome 3.
Matrix Biol.
18
155-161
1999
1165695
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
1165696
Friedrichs B.,Tepel C.,Reinheckel T.,Deussing J.,von Figura K.,Herzog V.,Peters C.,Saftig P.,Brix K.
Thyroid functions of mouse cathepsins B, K, and L.
J. Clin. Invest.
111
1733-1745
2003
