Sequence of C7DD6_HELAN
EC Number:1.14.14.169
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
6alpha,8beta-dihydroxygermacra-1(10),4,11(13)-trien-12-oate = eupatolide + H2O
Other sequences found for EC No. 1.14.14.169
General information:
Sequence
0 MDFLTYLPSW LLPAVVILTI SCILMLWTKP SKGASGLNLP PGPPSLPLIG NLHQLIGKSF
60 HETVYKLAEK YGPIMHIHMG SQPVVVISSS ALATEAFKTH DHILANRQYS NNLRRLTFDY
120 NDIAWAPYGD HSKHMRRVLV TEFLNSRMSK SFKKVLDMEV KSMLDNLPYG TETNLNKVFG
180 NFVCDFTSKV VTGKSYRDVK IRGKTMKEML DEMIILFSGS FSEIFPKYGW ILEDLSGWTR
240 RVDKHMANYN DLLELMIDEH LDHTSEDEKD MIDACRPLLN REEMKAIMSN VYNGAIDTSY
300 LTLVWAMSEI VKNPRVMHKL QDEIRSNAGN KARLDETDTS KMTYLKYVVK ETLRRHGPSP
360 FLIPRDCVSH IQIGGYDILP GTKVLINAWG IAKDPKVWTE NANEFHPDRF ENHVLEQFHM
420 VPFGGGRRAC PGYNFATLNI EVVLANLLYS IDWKLPPGLT LEDFNMEEEG SLLVTKKTPL
480 YLVPIKHNTQ A
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1164380
Ikezawa N.,Gopfert J.C.,Nguyen D.T.,Kim S.U.,O'Maille P.E.,Spring O.,Ro D.K.
Lettuce costunolide synthase (CYP71BL2) and its homolog (CYP71BL1) from sunflower catalyze distinct regio- and stereoselective hydroxylations in sesquiterpene lactone metabolism.
J. Biol. Chem.
286
21601-21611
2011
1164381
Badouin H.,Gouzy J.,Grassa C.J.,Murat F.,Staton S.E.,Cottret L.,Lelandais-Briere C.,Owens G.L.,Carrere S.,Mayjonade B.,Legrand L.,Gill N.,Kane N.C.,Bowers J.E.,Hubner S.,Bellec A.,Berard A.,Berges H.,Blanchet N.,Boniface M.C.,Brunel D.,Catrice O.,Chaidir N.,Claudel C.,Donnadieu C.,Faraut T.,Fievet G.,Helmstetter N.,King M.,Knapp S.J.,Lai Z.,Le Paslier M.C.,Lippi Y.,Lorenzon L.,Mandel J.R.,Marage G.,Marchand G.,Marquand E.,Bret-Mestries E.,Morien E.,Nambeesan S.,Nguyen T.,Pegot-Espagnet P.,Pouilly N.,Raftis F.,Sallet E.,Schiex T.,Thomas J.,Vandecasteele C.,Vares D.,Vear F.,Vautrin S.,Crespi M.,Mangin B.,Burke J.M.,Salse J.,Munos S.,Vincourt P.,Rieseberg L.H.,Langlade N.B.
The sunflower genome provides insights into oil metabolism, flowering and Asterid evolution.
Nature
546
148-152
2017
1164382
Frey M.,Schmauder K.,Pateraki I.,Spring O.
Biosynthesis of eupatolide-A metabolic route for sesquiterpene lactone formation involving the P450 enzyme CYP71DD6.
ACS Chem. Biol.
13
1536-1543
2018
