Sequence of ACVS_AMYLA
EC Number:6.3.2.26
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase
P27743
Amycolatopsis lactamdurans
3649
404088
Reaction
3 ATP + L-2-aminohexanedioate + L-cysteine + L-valine + H2O = 3 AMP + 3 diphosphate + N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine
Other sequences found for EC No. 6.3.2.26
General information:
Sequence
0 MTSARHLKSA ADWCARIDAI AGQRCDLEML LKDEWRHRVA VRDSDTAVRA TQEKELTISG
60 QDYTALKQAL GAMPLEAFAL ATLHSVLHAY GHGHQTVVAF LRDGKVLPVV VDHLEQAGLT
120 CAEAAEQLED AVAREDMYLP PEELLQRGLF DALLVLADGH LGFTELPPAP LVTIVRDDPA
180 AGCLHWRIAY AGEFFEDKII AGVLDVAREV LGQFIGRPEQ LVADIDLVSA EQELQLHQWN
240 GTDGEFDEDK RLNELFEDVV RRAPDREAVV CGDVRLTYRE VNERANQFAH WLIQGPVRVR
300 PGALIGLYLD KSDLGVVATF GIWKSGAAYV PIDPAYPAER IRFLVGDTGL SGIVTNRRHA
360 ERLREVLGDE HASVHVIEVE AVVAGPHPEQ ARENPGLALS SRDRAYVTYT SGTTGVPKGV
420 PKYHYSVVNS ITDLSERYDM RRPGTERVAL FASYVFEPHL RQTLIALINE QTLVIVPDDV
480 RLDPDLFPEY IERHGVTYLN ATGSVLQHFD LRRCASLKRL LLVGEELTAS GLRQLREKFA
540 GRVVNEYAFT EAAFVTAVKE FGPGVTERRD RSIGRPLRNV KWYVLSQGLK QLPIGAIGEL
600 YIGGCGVAPG YLNRDDLTAE RFTANPFQTE EEKARGRNGR LYRTGDLARV LLNGEVEFMG
660 RADFQLKLNG VRVEPGEIEA QATEFPGVKK CVVVAKENAT GDRHLVGYYL VEDGAEVAEA
720 DLIAFLEQRL IRIMVPARMV RLTSIPVNVN GKVDWRALPD VSLHPAPANA MNGALLAIDG
780 SNAPLLAITE QLRAIWSEVL GVPQNRIGER DDFFRLGGQS ISCILLIARV RQRLSLSLGV
840 EDVFALRTLD ALAGHLESQG HAEPEVVAEE VTTGSEPVRV LANGLQQGLL YHHLKTAGGD
900 DAYVVQSVHR YHAPIRPELM KDAWQAARQT YPALRLRFDW AEEPVQIVDN DDKPFDWRFV
960 DLSATADDAE QEARVRELQE RDRTEPYDLA GGRLFRVYLI KQREDLFSLI FSCHHIILDG
1020 WSLPVLHDEV HRNYLALRAG QPIESDVDNA YVAAQRYWEA HRNDHAAYWV EQLGRIDERG
1080 DFAGLLNEKS RYRVSLGDYD HVQRHRTRKL YLGADLTGAL KAGCAADQVT LHSVLQFVWH
1140 KVLHAIGGGN TTVVGTIVSG RNLPVDGIEN SAGLFINTLP LIVDHDQQAG QNVAEAVRDI
1200 QAAVNTMNSK SIVELGRLQS GEMKRRLFDT LLVLENYPRL LDEEEELAHQ EALRFEKAYD
1260 ADKVDYPIAV VAREEGDELT VTLWYAGELF DEDTIDTLLD VARTLFRQVT EDIARPVREL
1320 DLISPSMRAR FDSWNETAEE FPADKTLHAV FEEMAERWPD EIAVVYRENR LTYRELNERA
1380 NRLAHYLRSV VELRPDDLVA LVLDKSELMI TAIIAAWKTG AAYVPIDSGY PDDRISFMLS
1440 DTAARVVVTN EIHSDRLRSL AETGTPVLEI ELLHLDDQPA VNPVTETTST DLAYAIYTSG
1500 TTGKPKAVLV EHRGVVNLQV SLAKLFGLDK AHRDEALLSF SNYIFDHFVE QMTDALLNGQ
1560 KLVVLDDSMR TDPGRLCRYM NDEQVTYLSG TPSVLSLYDY SSATSLTRID AIGEDFTEPV
1620 FAKIRGTFPG LIINGYGPTE ISITSHKRPY PPDVHRVNKS IGFPVANTKC HVLNKAMKPV
1680 PVGGIGELYI GGIGVTRGYL NREDLTADRF VENPFQTAEE RRLGENGRLY KTGDLVRWLP
1740 NGEVEYLGRT DLQVKIRGQR VELGEVEAAL SSYPGVVRSL VVAREHAVGQ KYLVGFYVGE
1800 QEFDEQDLKQ WMRKKLPESV VPARVLRITD IPVTPSGKLD ARRLPETDFG AGEGAEYVAP
1860 VSEFELKLCG IWAQVLEIAP DRIGVHDDFF ALGGDSIRAM ALAQAITTGF GQGLGVATVL
1920 QHTTLAAQAE HIQAAALEHT AWTPPPTAVE HPPVSLAQER LLFIDDFEGG TAAYNIPFVL
1980 RLPAHTRAAL PGALGTLVRR HPALRTLLKT DDQGVRRQYP IPADDVRLEV PSTTVDSRAE
2040 LDEVLTERAG YVFRLHEELP IRAEAFDHGD EIYLSVVVHH SCFDGWSWDI FRRELAALLD
2100 GVPEADLGAL RGTYGEFAVW QRQYLTGKRL AALTEFWTGA LGGFETIALP LDHPRPPRFD
2160 YRGRELEFEL DERTTEALRE LARTARVSLY SVLLGAWCLM LNMYTGQHDL VVGTPSANRG
2220 RPEFDRAVGF FANLLALRVR VDPAATLPAY VRSVGEAVVA AQVHGELPFE QLVKELKVEK
2280 DPSRHPILQL NFTLQNVSDH TSALTGYQPD SGGWTTTKFD LSATMTETAT GLAGNLTYAA
2340 SLFDDTSASG FIATFKHVLA EFASAAAQTP IAQLTALDEP GQAALPDATR RARRPGGPGR
2400 CTRLFEEVAA TWPDRVAVVH GDVRLTYREL NERANRLAHH LRSVAEPRAD ELIALVLDKS
2460 ELTLVAILAV WKAGAAYMPI DPSYPDDRIA FMLSDTGAKL VLAGEAHGSR VRGLTSGDVL
2520 DLEQLDLTGE PAENPVTETT STELAYAIYT SGTTGKPKAV LVSHGSVDSF RAQLSGRYFG
2580 SPDESAEAVL FLANYVFDFS VEQLALSVLG GHKLLVPPPS AADDPAFYEL ANREGLSYLS
2640 GTPTQVERFD LARLSHLRCV LVAGEAFQPQ HFEKMRGEFA GPILNAYGTT ETTVYNTVHR
2700 FEPGDAYRNT LGAPLGNTRL YVLGDGMKLL PTGAVGELYL AGDCVTEGYL HRPELTRERF
2760 LPNPFAAESG RFPMIYRTGD VVRRGPDGEL QYLGRNDAQV KINGLRIEPG EVEAALAGCS
2820 GVRQCAVVAG ADPQAPERKR LVGYYLPEPG AAVDEADLFA ALRAQLMPSM VPSLLVRLDR
2880 PLPMTITGKL DVDALPSADF SPKRAAYAAP RDRVEARLCH LWSAQLPGGT VGIDDDFFRC
2940 GGDSISALHL ASQVQREIER KVSVKYLFDH PTVRSFVDNV LSGLAESSGD DEPEQGRLTG
3000 ECPMLPIQEW FFAKPLADRH RWNHNFAIRT PPLDPGELRT ALDRLVEHHD AFRLRFPESG
3060 GEVYAEDAAP ITLHELDVRG LADADLRQRL VDWQRTFDLA NGPTACAAYL HGFDDGTARV
3120 WFALHHLVVD TVSWHILAQD LEILYNGGDL GAKTGSYRQW AQAVRDYTPA EGEREFWAET
3180 TRDMESAELL AQTEGTTRRR EEFALTAPDT RTLLAESPWA YDTEVNDLLL TATGFALRSI
3240 TRQATNHLTV EGHGRELFEG APDVRDTVGW FTTMHPFAVE VDPGDLGRSV LATRANRRRV
3300 PHHGIGYGAL FGGEAPLPAV SFNYLGRLGE GDGQPTEAWQ LDPALSGSHT VDGNRLANRS
3360 SIDVTMSCTG GRLVAVVDSL LGEAATRLFA SELKVWLERL VSHTATVARN EPAREATTEL
3420 FDPYILVNED AERTLFVLPP GEGGAESYLS NLARQLPDLR LVLFNNVHLH TPMGSFEELG
3480 RYYVEHIRRL QPSGPYHLLG WSFGGVLSLE ISRQLARAGE RIDDLLLIDP YFGMRQASAN
3540 IGLPGVEDIL DPINYHYRPD EADLARLAGR LGNLVLFKAG EPNDVVNGPH QPRLFEYYHG
3600 TRFNHLDLLL PAAAIEVCDL AGETHHSWVR NEKLVRLMCE RISTSLGSD
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1154128
Coque J.J.R.,Martin J.F.,Calzada J.G.,Liras P.
The cephamycin biosynthetic genes pcbAB, encoding a large multidomain peptide synthetase, and pcbC of Nocardia lactamdurans are clustered together in an organization different from the same genes in Acremonium chrysogenum and Penicillium chrysogenum.
Mol. Microbiol.
5
1125-1133
1991
