Sequence of PLM1_PLAF7
EC Number:3.4.23.38
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
hydrolysis of the -Phe33-/-Leu- bond in the alpha-chain of hemoglobin, leading to denaturation of the molecule
Other sequences found for EC No. 3.4.23.38
General information:
Sequence
0 MALSIKEDFS SAFAKNESAV NSSTFNNNMK TWKIQKRFQI LYVFFFLLIT GALFYYLIDN
60 VLFPKNKKIN EIMNTSKHVI IGFSIENSHD RIMKTVKQHR LKNYIKESLK FFKTGLTQKP
120 HLGNAGDSVT LNDVANVMYY GEAQIGDNKQ KFAFIFDTGS ANLWVPSAQC NTIGCKTKNL
180 YDSNKSKTYE KDGTKVEMNY VSGTVSGFFS KDIVTIANLS FPYKFIEVTD TNGFEPAYTL
240 GQFDGIVGLG WKDLSIGSVD PVVVELKNQN KIEQAVFTFY LPFDDKHKGY LTIGGIEDRF
300 YEGQLTYEKL NHDLYWQVDL DLHFGNLTVE KATAIVDSGT SSITAPTEFL NKFFEGLDVV
360 KIPFLPLYIT TCNNPKLPTL EFRSATNVYT LEPEYYLQQI FDFGISLCMV SIIPVDLNKN
420 TFILGDPFMR KYFTVFDYDN HTVGFALAKK KL
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1100845
Gardner M.J.,Hall N.,Fung E.,White O.,Berriman M.,Hyman R.W.,Carlton J.M.,Pain A.,Nelson K.E.,Bowman S.,Paulsen I.T.,James K.D.,Eisen J.A.,Rutherford K.M.,Salzberg S.L.,Craig A.,Kyes S.,Chan M.-S.,Nene V.,Shallom S.J.,Suh B.,Peterson J.,Angiuoli S.,Pertea M.,Allen J.,Selengut J.,Haft D.,Mather M.W.,Vaidya A.B.,Martin D.M.A.,Fairlamb A.H.,Fraunholz M.J.,Roos D.S.,Ralph S.A.,McFadden G.I.,Cummings L.M.,Subramanian G.M.,Mungall C.,Venter J.C.,Carucci D.J.,Hoffman S.L.,Newbold C.,Davis R.W.,Fraser C.M.,Barrell B.G.
Genome sequence of the human malaria parasite Plasmodium falciparum.
Nature
419
498-511
2002
1100846
Klemba M.,Beatty W.,Gluzman I.,Goldberg D.E.
Trafficking of plasmepsin II to the food vacuole of the malaria parasite Plasmodium falciparum.
J. Cell Biol.
164
47-56
2004
1100847
Liu J.,Gluzman I.Y.,Drew M.E.,Goldberg D.E.
The role of Plasmodium falciparum food vacuole plasmepsins.
J. Biol. Chem.
280
1432-1437
2005
1100848
Mishra V.,Rathore I.,Arekar A.,Sthanam L.K.,Xiao H.,Kiso Y.,Sen S.,Patankar S.,Gustchina A.,Hidaka K.,Wlodawer A.,Yada R.Y.,Bhaumik P.
Deciphering the mechanism of potent peptidomimetic inhibitors targeting plasmepsins - biochemical and structural insights.
FEBS J.
285
3077-3096
2018
