Sequence of PGL1_CAEEL
EC Number:4.6.1.24
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
[RNA fragment]-3'-guanosine-2',3'-cyclophosphate + H2O = [RNA fragment]-3'-guanosine-3'-phosphate
Other sequences found for EC No. 4.6.1.24
General information:
Sequence
0 MEANKREIVD FGGLRSYFFP NLAHYITKND EELFNNTSQA NKLAAFVLGA SKDAPGDEDI
60 LEMILPNDAN AAVIAAGMDV CLLLGDKFRP KFDAAAEKLS GLGHAHDLVS VIDDDKKLGM
120 LARKAKLKKT EDAKILQALL KVIAIDDAAE KFVELTELVS QLDLDFDVYV LTKILGLISE
180 ETSDEVDIIR DNVVNAFDSC KPLLKQLMLD GPKSEPADPF ISLLMDPLEE SVGKVVNHIA
240 QLFEEASKNE GDESLVLRSQ LGYQLFFLIV RSLADGKREV SKKILSGIPT SVRAEVFPGL
300 QRSVYKSAVF LGNHIIQVLL GSKKSFEDWD VVGVAKDLES AWKRRAIAEL IKKFQVSILE
360 QCFDKPVPLI PQSPLNNDAV IDNVNKALQF ALWLTEFYGS ENETEALGEL RFLDSTSKNL
420 LVDSFKKFVQ GINSKTHVTR IVESLEKCCL SDTPSGRKSN VQPSTSQQQD SAYTKEEMTT
480 VHNTYSVNTK AQVLNGLSDT NSSGLLVDSK DSLSLQEISC DEVDSSTLLS SSRNIGEGVT
540 VKAVDPVPEK VNDAQQQQTV NEIEMASDAN QDTSSSASPE VAPSFSTDGW DSPTKSVALP
600 PGMQQIDEEE TTVADKDSTP QPQARAETAW GSGDATPMPL PAPTNQYKVS GFGEAKVAKG
660 FGQFAPTSSA YGGGGGRGGY GGGDRGGRGG YGGDRGGRGG YGGGDRGGRG GYGGDRGRGG
720 YGGRGGRGGF
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1099169
Kawasaki I.,Shim Y.-H.,Kirchner J.,Kaminker J.,Wood W.B.,Strome S.
pgl-1, a predicted RNA-binding component of germ granules, is essential for fertility in C. elegans.
Cell
94
635-645
1998
1099170
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science
282
2012-2018
1998
1099171
Amiri A.,Keiper B.D.,Kawasaki I.,Fan Y.,Kohara Y.,Rhoads R.E.,Strome S.
An isoform of eIF4E is a component of germ granules and is required for spermatogenesis in C. elegans.
Development
128
3899-3912
2001
1099172
Kawasaki I.,Amiri A.,Fan Y.,Meyer N.,Dunkelbarger S.,Motohashi T.,Karashima T.,Bossinger O.,Strome S.
The PGL family proteins associate with germ granules and function redundantly in Caenorhabditis elegans germline development.
Genetics
167
645-661
2004
1099173
Tian E.,Wang F.,Han J.,Zhang H.
epg-1 functions in autophagy-regulated processes and may encode a highly divergent Atg13 homolog in C. elegans.
Autophagy
5
608-615
2009
1099174
Zhang Y.,Yan L.,Zhou Z.,Yang P.,Tian E.,Zhang K.,Zhao Y.,Li Z.,Song B.,Han J.,Miao L.,Zhang H.
SEPA-1 mediates the specific recognition and degradation of P granule components by autophagy in C. elegans.
Cell
136
308-321
2009
1099175
Hanazawa M.,Yonetani M.,Sugimoto A.
PGL proteins self associate and bind RNPs to mediate germ granule assembly in C. elegans.
J. Cell Biol.
192
929-937
2011
1099176
Li S.,Yang P.,Tian E.,Zhang H.
Arginine methylation modulates autophagic degradation of PGL granules in C. elegans.
Mol. Cell
52
421-433
2013
1099177
Updike D.L.,Knutson A.K.,Egelhofer T.A.,Campbell A.C.,Strome S.
Germ-granule components prevent somatic development in the C. elegans germline.
Curr. Biol.
24
970-975
2014
1099178
Wang J.T.,Smith J.,Chen B.C.,Schmidt H.,Rasoloson D.,Paix A.,Lambrus B.G.,Calidas D.,Betzig E.,Seydoux G.
Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans.
Elife
3
0-0
2014
1099179
Min H.,Shim Y.H.,Kawasaki I.
Loss of PGL-1 and PGL-3, members of a family of constitutive germ-granule components, promotes germline apoptosis in C. elegans.
J. Cell Sci.
129
341-353
2016
1099180
Al-Amin M.,Min H.,Shim Y.H.,Kawasaki I.
Somatically expressed germ-granule components, PGL-1 and PGL-3, repress programmed cell death in C. elegans.
Sci. Rep.
6
33884-33884
2016
1099181
Zhang G.,Lin L.,Qi D.,Zhang H.
The composition of a protein aggregate modulates the specificity and efficiency of its autophagic degradation.
Autophagy
13
1487-1495
2017
1099182
Aoki S.T.,Kershner A.M.,Bingman C.A.,Wickens M.,Kimble J.
PGL germ granule assembly protein is a base-specific, single-stranded RNase.
Proc. Natl. Acad. Sci. U.S.A.
113
1279-1284
2016
1099183
Wang S.Y.,Mao H.,Shibuya H.,Uzawa S.,O'Brown Z.K.,Wesenberg S.,Shin N.,Saito T.T.,Gao J.,Meyer B.J.,Colaiacovo M.P.,Greer E.L.
The demethylase NMAD-1 regulates DNA replication and repair in the Caenorhabditis elegans germline.
PLoS Genet.
15
0-0
2019
1099184
Suen K.M.,Braukmann F.,Butler R.,Bensaddek D.,Akay A.,Lin C.C.,Milonaityte D.,Doshi N.,Sapetschnig A.,Lamond A.,Ladbury J.E.,Miska E.A.
DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans.
Nat. Commun.
11
4242-4242
2020
