Sequence of KANE_STRKN
EC Number:2.4.1.301
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase
Q65CC7
Streptomyces kanamyceticus
386
43218
Reaction
UDP-alpha-D-kanosamine + 2'-deamino-2'-hydroxyneamine = UDP + kanamycin A
Other sequences found for EC No. 2.4.1.301
General information:
Sequence
0 MHLLVRALVE EMAGRGVPHR VLTMSPPKVP KDIRIGQRIK VHARRLPVLP IPSDLEGYFG
60 LVGAWAKGSL LWVLRNRKRL RREIGARVHA HCDGSGAAAF YPYLMSRILG VPLVVQIHSS
120 RYLSQHPTTL FERVTDPIAK WAERHAVRKA AAVLMLTDRA RDEMRRKAQL PAERVHRLAY
180 LASDQFKDAD TEARRAELRE RYGLDDRPIV LYVGRIAAEK GVEYYIEAAA ELTRRGRDCQ
240 FVIAGDGPAR PDLEKLIGAR GLRDRVTITG FMSHEFIPSM ISLGELVVLP SRYEELGIVI
300 LECMTMRRPL VAHDVNGVNK LIEDGTTGIV VPPFRTPEMA DAVERLLDDP ELRERMAENA
360 APLPAAKYSL SAAGDQLAGI YREIGL
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1075080
Kharel M.K.,Subba B.,Basnet D.B.,Woo J.S.,Lee H.C.,Liou K.,Sohng J.K.
A gene cluster for biosynthesis of kanamycin from Streptomyces kanamyceticus: comparison with gentamicin biosynthetic gene cluster.
Arch. Biochem. Biophys.
429
204-214
2004
1075081
Park J.W.,Park S.R.,Nepal K.K.,Han A.R.,Ban Y.H.,Yoo Y.J.,Kim E.J.,Kim E.M.,Kim D.,Sohng J.K.,Yoon Y.J.
Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
Nat. Chem. Biol.
7
843-852
2011
