Sequence of SCYD_MAGO7

scytalone dehydratase

P56221

172

20250

97937

Motoyama T.,Imanishi K.,Yamaguchi I.

cDNA cloning, expression, and mutagenesis of scytalone dehydratase needed for pathogenicity of the rice blast fungus, Pyricularia oryzae.

Biosci. Biotechnol. Biochem.

62

564-566

1998

97938

Dean R.A.,Talbot N.J.,Ebbole D.J.,Farman M.L.,Mitchell T.K.,Orbach M.J.,Thon M.R.,Kulkarni R.,Xu J.-R.,Pan H.,Read N.D.,Lee Y.-H.,Carbone I.,Brown D.,Oh Y.Y.,Donofrio N.,Jeong J.S.,Soanes D.M.,Djonovic S.,Kolomiets E.,Rehmeyer C.,Li W.,Harding M.,Kim S.,Lebrun M.-H.,Bohnert H.,Coughlan S.,Butler J.,Calvo S.E.,Ma L.-J.,Nicol R.,Purcell S.,Nusbaum C.,Galagan J.E.,Birren B.W.

The genome sequence of the rice blast fungus Magnaporthe grisea.

Nature

434

980-986

2005

97939

Kim S.T.,Yu S.,Kim S.G.,Kim H.J.,Kang S.Y.,Hwang D.H.,Jang Y.S.,Kang K.Y.

Proteome analysis of rice blast fungus (Magnaporthe grisea) proteome during appressorium formation.

Proteomics

4

3579-3587

2004

97940

Lundqvist T.,Weber P.C.,Hodge C.N.,Braswell E.H.,Rice J.,Pierce J.

Preliminary crystallographic studies on scytalone dehydratase from Magnaporthe grisea.

J. Mol. Biol.

232

999-1002

1993

97941

Thompson J.E.,Basarab G.S.,Pierce J.,Hodge C.N.,Jordan D.B.

2,3-Dihydro-2,5-dihydroxy-4H-benzopyran-4-one: a nonphysiological substrate for fungal melanin biosynthetic enzymes.

Anal. Biochem.

256

1-6

1998

97942

Thompson J.E.,Jordan D.B.

Partition analysis of an enzyme acting concurrently upon two substrates in a continuous multiwavelength assay.

Anal. Biochem.

256

7-13

1998

97943

Zheng Y.J.,Bruice T.C.

Role of a critical water in scytalone dehydratase-catalyzed reaction.

Proc. Natl. Acad. Sci. U.S.A.

95

4158-4163

1998

97944

Basarab G.S.,Steffens J.J.,Wawrzak Z.,Schwartz R.S.,Lundqvist T.,Jordan D.B.

Catalytic mechanism of scytalone dehydratase: site-directed mutagenesis, kinetic isotope effects, and alternate substrates.

Biochemistry

38

6012-6024

1999

97945

Jordan D.B.,Lessen T.A.,Wawrzak Z.,Bisaha J.J.,Gehret T.C.,Hansen S.L.,Schwartz R.S.,Basarab G.S.

Design of scytalone dehydratase inhibitors as rice blast fungicides: (N-phenoxypropyl)-carboxamides.

Bioorg. Med. Chem. Lett.

9

1607-1612

1999

97946

Basarab G.S.,Jordan D.B.,Gehret T.C.,Schwartz R.S.,Wawrzak Z.

Design of scytalone dehydratase inhibitors as rice blast fungicides: derivatives of norephedrine.

Bioorg. Med. Chem. Lett.

9

1613-1618

1999

97947

Jordan D.B.,Zheng Y.J.,Lockett B.A.,Basarab G.S.

Stereochemistry of the enolization of scytalone by scytalone dehydratase.

Biochemistry

39

2276-2282

2000

97948

Jordan D.B.,Basarab G.S.,Steffens J.J.,Schwartz R.S.,Doughty J.G.

Tight binding inhibitors of scytalone dehydratase: effects of site-directed mutations.

Biochemistry

39

8593-8602

2000

97949

Jordan D.B.,Basarab G.S.

Binding dynamics of two water molecules constrained within the scytalone dehydratase binding pocket.

Bioorg. Med. Chem. Lett.

10

23-26

2000

97950

Jennings L.D.,Rayner D.R.,Jordan D.B.,Okonya J.F.,Basarab G.S.,Amorose D.K.,Anaclerio B.M.,Lee J.K.,Schwartz R.S.,Whitmore K.A.

Cyclobutane carboxamide inhibitors of fungal melanin: biosynthesis and their evaluation as fungicides.

Bioorg. Med. Chem.

8

897-907

2000

97951

Zheng Y.J.,Basarab G.S.,Jordan D.B.

Roles of substrate distortion and intramolecular hydrogen bonding in enzymatic catalysis by scytalone dehydratase.

Biochemistry

41

820-826

2002

97952

Basarab G.S.,Jordan D.B.,Gehret T.C.,Schwartz R.S.

Design of inhibitors of scytalone dehydratase: probing interactions with an asparagine carboxamide.

Bioorg. Med. Chem.

10

4143-4154

2002

97953

Yamada N.,Motoyama T.,Nakasako M.,Kagabu S.,Kudo T.,Yamaguchi I.

Enzymatic characterization of scytalone dehydratase Val75Met variant found in melanin biosynthesis dehydratase inhibitor (MBI-D) resistant strains of the rice blast fungus.

Biosci. Biotechnol. Biochem.

68

615-621

2004

97954

Takagaki M.,Kaku K.,Watanabe S.,Kawai K.,Shimizu T.,Sawada H.,Kumakura K.,Nagayama K.

Mechanism of resistance to carpropamid in Magnaporthe grisea.

Pest Manag. Sci.

60

921-926

2004

97955

Lundqvist T.,Rice J.,Hodge C.N.,Basarab G.S.,Pierce J.,Lindqvist Y.

Crystal structure of scytalone dehydratase -- a disease determinant of the rice pathogen, Magnaporthe grisea.

Structure

2

937-944

1994

97956

Nakasako M.,Motoyama T.,Kurahashi Y.,Yamaguchi I.

Cryogenic X-ray crystal structure analysis for the complex of scytalone dehydratase of a rice blast fungus and its tight-binding inhibitor, carpropamid: the structural basis of tight-binding inhibition.

Biochemistry

37

9931-9939

1998

97957

Chen J.M.,Xu S.L.,Wawrzak Z.,Basarab G.S.,Jordan D.B.

Structure-based design of potent inhibitors of scytalone dehydratase: displacement of a water molecule from the active site.

Biochemistry

37

17735-17744

1998

97958

Wawrzak Z.,Sandalova T.,Steffens J.J.,Basarab G.S.,Lundqvist T.,Lindqvist Y.,Jordan D.B.

High-resolution structures of scytalone dehydratase-inhibitor complexes crystallized at physiological pH.

Proteins

35

425-439

1999

97959

Motoyama T.,Nakasako M.,Yamaguchi I.

Crystallization of scytalone dehydratase F162A mutant in the unligated state and a preliminary X-ray diffraction study at 37 K.

Acta Crystallogr. D

58

148-150

2002