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Sequence of CPXA_PSEPU

EC Number:1.14.15.1

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
camphor 5-monooxygenase
P00183
Pseudomonas putida
415
46669
Reaction
(+)-camphor + reduced putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O
Other sequences found for EC No. 1.14.15.1

General information:

Sequence
show sequence in fasta format
  0 MTTETIQSNA NLAPLPPHVP EHLVFDFDMY NPSNLSAGVQ EAWAVLQESN VPDLVWTRCN
 60 GGHWIATRGQ LIREAYEDYR HFSSECPFIP REAGEAYDFI PTSMDPPEQR QFRALANQVV
120 GMPVVDKLEN RIQELACSLI ESLRPQGQCN FTEDYAEPFP IRIFMLLAGL PEEDIPHLKY
180 LTDQMTRPDG SMTFAEAKEA LYDYLIPIIE QRRQKPGTDA ISIVANGQVN GRPITSDEAK
240 RMCGLLLVGG LDTVVNFLSF SMEFLAKSPE HRQELIERPE RIPAACEELL RRFSLVADGR
300 ILTSDYEFHG VQLKKGDQIL LPQMLSGLDE RENACPMHVD FSRQKVSHTT FGHGSHLCLG
360 QHLARREIIV TLKEWLTRIP DFSIAPGAQI QHKSGIVSGV QALPLVWDPA TTKAV
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1044848
Unger B.P.,Gunsalus I.C.,Sligar S.G.
Nucleotide sequence of the Pseudomonas putida cytochrome P-450cam gene and its expression in Escherichia coli.
J. Biol. Chem.
261
1158-1163
1986
1044849
Koga H.,Yamaguchi E.,Matsunaga K.,Aramaki H.,Horiuchi T.
Cloning and nucleotide sequences of NADH-putidaredoxin reductase gene (camA) and putidaredoxin gene (camB) involved in cytochrome P-450cam hydroxylase of Pseudomonas putida.
J. Biochem.
106
831-836
1989
1044850
Haniu M.,Armes L.G.,Yasunobu K.T.,Shastry B.A.,Gunsalus I.C.
Amino acid sequence of the Pseudomonas putida cytochrome P-450. II. Cyanogen bromide peptides, acid cleavage peptides, and the complete sequence.
J. Biol. Chem.
257
12664-12671
1982
1044851
Marden M.C.,Hui Bon Hoa G.
P-450 binding to substrates camphor and linalool versus pressure.
Arch. Biochem. Biophys.
253
100-107
1987
1044853
Hui Bon Hoa G.,Di Primo C.,Dondaine I.,Sligar S.G.,Gunsalus I.C.,Douzou P.
Conformational changes of cytochromes P-450cam and P-450lin induced by high pressure.
Biochemistry
28
651-656
1989
1044854
Nolting B.,Jung C.,Snatzke G.
Multichannel circular dichroism investigations of the structural stability of bacterial cytochrome P-450.
Biochim. Biophys. Acta
1100
171-176
1992
1044855
Deprez E.,Gill E.,Helms V.,Wade R.,Hui Bon Hoa G.
Specific and non-specific effects of potassium cations on substrate-protein interactions in cytochromes P450cam and P450lin.
J. Inorg. Biochem.
91
597-606
2002
1044856
Poulos T.L.,Finzel B.C.,Gunsalus I.C.,Wagner G.C.,Kraut J.
The 2.6-A crystal structure of Pseudomonas putida cytochrome P-450.
J. Biol. Chem.
260
16122-16130
1985
1044857
Schlichting I.,Jung C.,Schulze H.
Crystal structure of cytochrome P-450cam complexed with the (1S)-camphor enantiomer.
FEBS Lett.
415
253-257
1997
1044859
Vidakovic M.,Sligar S.G.,Li H.,Poulos T.L.
Understanding the role of the essential Asp251 in cytochrome p450cam using site-directed mutagenesis, crystallography, and kinetic solvent isotope effect.
Biochemistry
37
9211-9219
1998
1044860
Dmochowski I.J.,Crane B.R.,Wilker J.J.,Winkler J.R.,Gray H.B.
Optical detection of cytochrome P450 by sensitizer-linked substrates.
Proc. Natl. Acad. Sci. U.S.A.
96
12987-12990
1999
1044861
Schlichting I.,Berendzen J.,Chu K.,Stock A.M.,Maves S.A.,Benson D.E.,Sweet R.M.,Ringe D.,Petsko G.A.,Sligar S.G.
The catalytic pathway of cytochrome p450cam at atomic resolution.
Science
287
1615-1622
2000
1044862
Hishiki T.,Shimada H.,Nagano S.,Egawa T.,Kanamori Y.,Makino R.,Park S.-Y.,Adachi S.,Shiro Y.,Ishimura Y.
X-ray crystal structure and catalytic properties of Thr252Ile mutant of cytochrome P450cam: roles of Thr252 and water in the active center.
J. Biochem.
128
965-974
2000
1044863
Lee D.-S.,Park S.-Y.,Yamane K.,Obayashi E.,Hori H.,Shiro Y.
Structural characterization of n-butyl-isocyanide complexes of cytochromes P450nor and P450cam.
Biochemistry
40
2669-2677
2001
1044864
Dunn A.R.,Dmochowski I.J.,Bilwes A.M.,Gray H.B.,Crane B.R.
Probing the open state of cytochrome P450cam with ruthenium-linker substrates.
Proc. Natl. Acad. Sci. U.S.A.
98
12420-12425
2001
1044865
Fedorov R.,Ghosh D.K.,Schlichting I.
Crystal structures of cyanide complexes of P450cam and the oxygenase domain of inducible nitric oxide synthase -- structural models of the short-lived oxygen complexes.
Arch. Biochem. Biophys.
409
25-31
2003
1044866
Mouro C.,Bondon A.,Simmoneaux G.,Jung C.
1H-NMR study of diamagnetic cytochrome P450cam: assignment of heme resonances and substrate dependance of one cysteinate beta proton.
FEBS Lett.
414
203-208
1997