Sequence of CAS4_PYRCJ
EC Number:3.1.12.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming)
A3MTK6
Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1)
213
24673
Reaction
exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 3'-phosphates
Other sequences found for EC No. 3.1.12.1
General information:
Sequence
0 MELLSPKPLC SVVNCEDLEK LDHVSALNEL RREQEIFKLL PGIYAHRYDF RRVSPSIIND
60 FEYCPRLLWV QHKLGLKLLS EKSVVSIIRG RILHERYERL LSQYENVVAE YKVEIGDLVG
120 VVDLVIKRGG EYIPVEIKTG FSKEAHKTQL QIYISMLKAR FGYLVYRNHV EVVHRNDAAL
180 DVLKKIREIL SAREAPPAKC NSCIFKPICK NLL
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1037596
Lemak S.,Beloglazova N.,Nocek B.,Skarina T.,Flick R.,Brown G.,Popovic A.,Joachimiak A.,Savchenko A.,Yakunin A.F.
Toroidal structure and DNA cleavage by the CRISPR-associated [4Fe-4S] cluster containing Cas4 nuclease SSO0001 from Sulfolobus solfataricus.
J. Am. Chem. Soc.
135
17476-17487
2013
1037597
Lemak S.,Nocek B.,Beloglazova N.,Skarina T.,Flick R.,Brown G.,Joachimiak A.,Savchenko A.,Yakunin A.F.
The CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis contains a [2Fe-2S] cluster: crystal structure and nuclease activity.
Nucleic Acids Res.
42
11144-11155
2014
