Sequence of MNLOX_GAEAV
EC Number:1.13.11.45
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
linoleate + O2 = (9Z,12Z)-(11S)-11-hydroperoxyoctadeca-9,12-dienoate
Other sequences found for EC No. 1.13.11.45
General information:
Sequence
0 MRSRILAIVF AARHVAALPL AAEDAAATLS LTSSASSTTV LPSPTQYTLP NNDPNQGARN
60 ASIARKRELF LYGPSTLGQT TFYPTGELGN NISARDVLLW RQDAANQTAT AYREANETFA
120 DITSRGGFKT LDDFALLYNG HWKESVPEGI SKGMLSNCTS DLLFSMERLS SNPYVLKRLH
180 PTKDKLPFSV ESKVVKKLTA TTLEALHKGG RLFLVDHSYQ KKYTPQPGRY AAACQGLFYL
240 DARSNQFLPL AIKTNVGVDL TYTPLDDKDD WLLAKIMFNN NDLFYSQMYH VLFHTIPEIV
300 HEAAFRTLSD RHPVMGVLNR LMYQAYAIRP VGGAVLFNPG GFWDQNFGLP ASAAIDFPGS
360 VYAQGGGGFQ AGYLEKDLRS RGLIGEDSGP RLPHFPFYED AHRLIGAIRR FMQAFVDSTY
420 GADDGDDGAL LRDYELQNWI AEANGPAQVR DFPAAPLRRR AQLVDVLTHV AWITGGAHHV
480 MNQGSPVKFS GVLPLHPAAL YAPIPTAKGA TGNGTRAGLL AWLPNERQAV EQVSLLARFN
540 RAQVGDRKQT VRDAFAAPDL LAGNGPGYAA ANARFVEDTG RISREIAGRG FDGKGLSQGM
600 PFVWTALNPA VNPFFLSV
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
955125
Hornsten L.,Su C.,Osbourn A.E.,Hellman U.,Oliw E.H.
Cloning of the manganese lipoxygenase gene reveals homology with the lipoxygenase gene family.
Eur. J. Biochem.
269
2690-2697
2002
955126
Wennman A.,Jerneren F.,Hamberg M.,Oliw E.H.
Catalytic convergence of manganese and iron lipoxygenases by replacement of a single amino acid.
J. Biol. Chem.
287
31757-31765
2012
955127
Su C.,Oliw E.H.
Manganese lipoxygenase. Purification and characterization.
J. Biol. Chem.
273
13072-13079
1998
955128
Cristea M.,Engstroem K.,Su C.,Hoernsten L.,Oliw E.H.
Expression of manganese lipoxygenase in Pichia pastoris and site-directed mutagenesis of putative metal ligands.
Arch. Biochem. Biophys.
434
201-211
2005
955129
Cristea M.,Oliw E.H.
A G316A mutation of manganese lipoxygenase augments hydroperoxide isomerase activity: mechanism of biosynthesis of epoxyalcohols.
J. Biol. Chem.
281
17612-17623
2006
955130
Oliw E.H.
Factors influencing the rearrangement of bis-allylic hydroperoxides by manganese lipoxygenase.
J. Lipid Res.
49
420-428
2008
955131
Wennman A.,Oliw E.H.
Secretion of two novel enzymes, manganese 9S-lipoxygenase and epoxy alcohol synthase, by the rice pathogen Magnaporthe salvinii.
J. Lipid Res.
54
762-775
2013
955132
Chen Y.,Wennman A.,Karkehabadi S.,Engstroem A.,Oliw E.H.
Crystal structure of linoleate 13R-manganese lipoxygenase in complex with an adhesion protein.
J. Lipid Res.
57
1574-1588
2016
