Sequence of PUR2_CRYNH
EC Number:6.3.4.13
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
phosphoribosylamine-glycine ligase
J9VYP5
Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
802
84591
Reaction
ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N1-(5-phospho-D-ribosyl)glycinamide
Other sequences found for EC No. 6.3.4.13
General information:
Sequence
0 MPEITAFPQP KSDLSILLLG AGGREHALAF KLAQSSRVAR IVVCPGNGGT ALMGGKVSNL
60 ALPWGAPPAF RSIVEWAQKE NIDLVVPGPE QPLVDGVEGA FKKVGIPVFG PSPAAAMLEG
120 SKSLSKEFMA RHNIPTAAFR SFTSTQYEDA VAYIKSKPFT SGRSVIKASG LAAGKGVLIP
180 ETDEEAFAAL KSVMVDKEFG DAGDEVVVEE YLSGPEISVL AFSDGYTIVP MPAAQDHKRI
240 GEGDTGLNTG GMGAYAPAPI ATKEIMERCV KDVLEPTIKG MREDGYPFVG MLFTGFMITA
300 DGPRVLEYNV RFGDPETQAL MLLLDEQTDL AEVLLACVER RLDSIKLGYK QGYAVSVVLA
360 SEGYPGSYPK GLPMTLNPTP EGVEVFHAGT KRSDNVTVTD GGRVLAVCAS APTLRAAVDL
420 AYSGISQISF QGQTFRRDIA YRALSSEPPA EPKGLTYAAA GVSVDAGNDL VEAIKPVVKA
480 TRRPGADSDI GGFGGAFDLA KAGYKDPILV SGTDGVGTKL RVALDHGKHN TVGIDLVAMS
540 VNDLIVQGAE PLYFLDYYAC SKLDVPVAAD VITGIAEGCL QAGCALIGGE TAEMPGMYHG
600 DDYDLAGFAV GVVERAQILP TPDIASGDVL LALSSSGPHS NGFSLIRKIV SLSNLSLHDT
660 APWDKNTSVG DALLTPTKVY IKPLLPGIKS GLYKGMSHIT GGGFTENIPR IFSSASNLGV
720 KLDLTSYSLP AIWKWLMRAG NVEAKEMVRT FNCGVGMIII VAKDKADAAL SSLKENGEEA
780 WVIGEVQEKK GVEYVGLDKF GL
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
80905
Janbon G.,Ormerod K.L.,Paulet D.,Byrnes E.J. III,Yadav V.,Chatterjee G.,Mullapudi N.,Hon C.-C.,Billmyre R.B.,Brunel F.,Bahn Y.-S.,Chen W.,Chen Y.,Chow E.W.L.,Coppee J.-Y.,Floyd-Averette A.,Gaillardin C.,Gerik K.J.,Goldberg J.,Gonzalez-Hilarion S.,Gujja S.,Hamlin J.L.,Hsueh Y.-P.,Ianiri G.,Jones S.,Kodira C.D.,Kozubowski L.,Lam W.,Marra M.,Mesner L.D.,Mieczkowski P.A.,Moyrand F.,Nielsen K.,Proux C.,Rossignol T.,Schein J.E.,Sun S.,Wollschlaeger C.,Wood I.A.,Zeng Q.,Neuveglise C.,Newlon C.S.,Perfect J.R.,Lodge J.K.,Idnurm A.,Stajich J.E.,Kronstad J.W.,Sanyal K.,Heitman J.,Fraser J.A.,Cuomo C.A.,Dietrich F.S.
Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation.
PLoS Genet.
10
0-0
2014
80906
Chua S.M.H.,Wizrah M.S.I.,Luo Z.,Lim B.Y.J.,Kappler U.,Kobe B.,Fraser J.A.
Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets.
J. Biol. Chem.
297
101091-101091
2021
