Sequence of TERA1_CAEEL
EC Number:3.6.4.6
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + H2O = ADP + phosphate
Other sequences found for EC No. 3.6.4.6
General information:
Sequence
0 MASVPTHQSE KEKKNDELST AILKDKVKPN RLIVDQSEQD DNSVIAVSQA KMDELGLFRG
60 DAVILKGKKR KESVAIIVSD ESCPNEKVRM NRVVRNNLRI RLGDVVSITP APNLSYGTRI
120 HVLPIDDTIE GLTGNLFDVF LKPYFLEAYR PLHKGDIFTV QAAMRTVEFK VVETEPAPAC
180 IVSPDTMIHY EGDPIKREEE EESMNDIGYD DLGGVRKQLA QIKEMVELPL RHPQLFKAIG
240 IKPPRGILLF GPPGTGKTLI ARAVANETGS FFFLINGPEV MSKMSGESES NLRKAFEECE
300 KNQPAILFID EIDAIAPKRE KTNGEVERRI VSQLLTLMDG VKGRSNLVVI AATNRPNSID
360 GALRRFGRFD REIDIGIPDA VGRLEILRIH TKNMKLADDV DLEQIANECH GFVGADLASL
420 CSEAALQQIR EKMELIDLED DQIDAEVLNS LAVTMENFRF AQGKSSPSAL REAVVETPNT
480 TWSDIGGLQN VKRELQELVQ YPVEHPEKYL KFGMQPSRGV LFYGPPGCGK TLLAKAIANE
540 CQANFISIKG PELLTMWFGE SEANVRDVFD KARAAAPCVL FFDELDSIAK ARGGGAGGDG
600 GGASDRVINQ VLTEMDGMNA KKNVFIIGAT NRPDIIDPAV LRPGRLDQLI YIPLPDEASR
660 HQILKASLRK TPLSKDLDLT FLAKNTVGFS GADLTEICQR ACKLAIRESI EKEIRIEKER
720 QDRQARGEEL MEDDAVDPVP EITRAHFEEA MKFARRSVTD NDIRKYEMFA QTLQQSRGFG
780 NNFKFPGEQR GSDAPSAPVP AQDDDDLYN
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
873589
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science
282
2012-2018
1998
873590
Poteryaev D.,Squirrell J.M.,Campbell J.M.,White J.G.,Spang A.
Involvement of the actin cytoskeleton and homotypic membrane fusion in ER dynamics in Caenorhabditis elegans.
Mol. Biol. Cell
16
2139-2153
2005
873591
Yamauchi S.,Yamanaka K.,Ogura T.
Comparative analysis of expression of two p97 homologues in Caenorhabditis elegans.
Biochem. Biophys. Res. Commun.
345
746-753
2006
873592
Mouysset J.,Kaehler C.,Hoppe T.
A conserved role of Caenorhabditis elegans CDC-48 in ER-associated protein degradation.
J. Struct. Biol.
156
41-49
2006
873593
Sasagawa Y.,Yamanaka K.,Nishikori S.,Ogura T.
Caenorhabditis elegans p97/CDC-48 is crucial for progression of meiosis I.
Biochem. Biophys. Res. Commun.
358
920-924
2007
873594
Sasagawa Y.,Yamanaka K.,Ogura T.
ER E3 ubiquitin ligase HRD-1 and its specific partner chaperone BiP play important roles in ERAD and developmental growth in Caenorhabditis elegans.
Genes Cells
12
1063-1073
2007
873595
Ramadan K.,Bruderer R.,Spiga F.M.,Popp O.,Baur T.,Gotta M.,Meyer H.H.
Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin.
Nature
450
1258-1262
2007
873596
Janiesch P.C.,Kim J.,Mouysset J.,Barikbin R.,Lochmueller H.,Cassata G.,Krause S.,Hoppe T.
The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathy.
Nat. Cell Biol.
9
379-390
2007
873597
Heallen T.R.,Adams H.P.,Furuta T.,Verbrugghe K.J.,Schumacher J.M.
An Afg2/Spaf-related Cdc48-like AAA ATPase regulates the stability and activity of the C. elegans Aurora B kinase AIR-2.
Dev. Cell
15
603-616
2008
873598
Nishikori S.,Yamanaka K.,Sakurai T.,Esaki M.,Ogura T.
p97 Homologs from Caenorhabditis elegans, CDC-48.1 and CDC-48.2, suppress the aggregate formation of huntingtin exon1 containing expanded polyQ repeat.
Genes Cells
13
827-838
2008
873599
Caruso M.E.,Jenna S.,Bouchecareilh M.,Baillie D.L.,Boismenu D.,Halawani D.,Latterich M.,Chevet E.
GTPase-mediated regulation of the unfolded protein response in Caenorhabditis elegans is dependent on the AAA+ ATPase CDC-48.
Mol. Cell. Biol.
28
4261-4274
2008
873600
Mouysset J.,Deichsel A.,Moser S.,Hoege C.,Hyman A.A.,Gartner A.,Hoppe T.
Cell cycle progression requires the CDC-48UFD-1/NPL-4 complex for efficient DNA replication.
Proc. Natl. Acad. Sci. U.S.A.
105
12879-12884
2008
873601
Rodrigues A.J.,Neves-Carvalho A.,Ferro A.,Rokka A.,Corthals G.,Logarinho E.,Maciel P.
ATX-3, CDC-48 and UBXN-5: a new trimolecular complex in Caenorhabditis elegans.
Biochem. Biophys. Res. Commun.
386
575-581
2009
873602
Sasagawa Y.,Otani M.,Higashitani N.,Higashitani A.,Sato K.,Ogura T.,Yamanaka K.
Caenorhabditis elegans p97 controls germline-specific sex determination by controlling the TRA-1 level in a CUL-2-dependent manner.
J. Cell Sci.
122
3663-3672
2009
873603
Sasagawa Y.,Yamanaka K.,Saito-Sasagawa Y.,Ogura T.
Caenorhabditis elegans UBX cofactors for CDC-48/p97 control spermatogenesis.
Genes Cells
15
1201-1215
2010
873604
Nishikori S.,Esaki M.,Yamanaka K.,Sugimoto S.,Ogura T.
Positive cooperativity of the p97 AAA ATPase is critical for essential functions.
J. Biol. Chem.
286
15815-15820
2011
873605
Franz A.,Orth M.,Pirson P.A.,Sonneville R.,Blow J.J.,Gartner A.,Stemmann O.,Hoppe T.
CDC-48/p97 coordinates CDT-1 degradation with GINS chromatin dissociation to ensure faithful DNA replication.
Mol. Cell
44
85-96
2011
873606
Kuhlbrodt K.,Janiesch P.C.,Kevei E.,Segref A.,Barikbin R.,Hoppe T.
The Machado-Joseph disease deubiquitylase ATX-3 couples longevity and proteostasis.
Nat. Cell Biol.
13
273-281
2011
873607
Miedel M.T.,Graf N.J.,Stephen K.E.,Long O.S.,Pak S.C.,Perlmutter D.H.,Silverman G.A.,Luke C.J.
A pro-cathepsin L mutant is a luminal substrate for endoplasmic-reticulum-associated degradation in C. elegans.
PLoS ONE
7
0-0
2012
873608
Kress E.,Schwager F.,Holtackers R.,Seiler J.,Prodon F.,Zanin E.,Eiteneuer A.,Toya M.,Sugimoto A.,Meyer H.,Meraldi P.,Gotta M.
The UBXN-2/p37/p47 adaptors of CDC-48/p97 regulate mitosis by limiting the centrosomal recruitment of Aurora A.
J. Cell Biol.
201
559-575
2013
873609
Noi K.,Yamamoto D.,Nishikori S.,Arita-Morioka K.,Kato T.,Ando T.,Ogura T.
High-speed atomic force microscopic observation of ATP-dependent rotation of the AAA+ chaperone p97.
Structure
21
1992-2002
2013
873610
Murayama Y.,Ogura T.,Yamanaka K.
Characterization of C-terminal adaptors, UFD-2 and UFD-3, of CDC-48 on the polyglutamine aggregation in C. elegans.
Biochem. Biophys. Res. Commun.
459
154-160
2015
873611
Marza E.,Taouji S.,Barroso K.,Raymond A.A.,Guignard L.,Bonneu M.,Pallares-Lupon N.,Dupuy J.W.,Fernandez-Zapico M.E.,Rosenbaum J.,Palladino F.,Dupuy D.,Chevet E.
Genome-wide screen identifies a novel p97/CDC-48-dependent pathway regulating ER-stress-induced gene transcription.
EMBO Rep.
16
332-340
2015
873612
Franz A.,Pirson P.A.,Pilger D.,Halder S.,Achuthankutty D.,Kashkar H.,Ramadan K.,Hoppe T.
Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression.
Nat. Commun.
7
10612-10612
2016
873613
Ackermann L.,Schell M.,Pokrzywa W.,Kevei E.,Gartner A.,Schumacher B.,Hoppe T.
E4 ligase-specific ubiquitination hubs coordinate DNA double-strand-break repair and apoptosis.
Nat. Struct. Mol. Biol.
23
995-1002
2016
873614
Sonneville R.,Moreno S.P.,Knebel A.,Johnson C.,Hastie C.J.,Gartner A.,Gambus A.,Labib K.
CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis.
Nat. Cell Biol.
19
468-479
2017
