Sequence of PLMT_YEAST
EC Number:2.1.1.71
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
phosphatidyl-N-methylethanolamine N-methyltransferase
P05375
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
206
23150
Reaction
S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine
Other sequences found for EC No. 2.1.1.71
General information:
Sequence
0 MKESVQEIIQ QLIHSVDLQS SKFQLAIVCT MFNPIFWNIV ARMEYHKHSL TKMCGGARKG
60 CYMLAATIFS LGIVRDMVYE SALREQPTCS LITGENWTKL GVALFGLGQV LVLSSMYKLG
120 ITGTYLGDYF GILMDERVTG FPFNVSNNPM YQGSTLSFLG IALYKGKPAG LVVSAVVYFM
180 YKIALRWEEP FTAMIYANRD KAKKNM
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
841387
Kodaki T.,Yamashita S.
Yeast phosphatidylethanolamine methylation pathway. Cloning and characterization of two distinct methyltransferase genes.
J. Biol. Chem.
262
15428-15435
1987
841388
Huang M.-E.,Manus V.,Chuat J.-C.,Galibert F.
Analysis of a 62 kb DNA sequence of chromosome X reveals 36 open reading frames and a gene cluster with a counterpart on chromosome XI.
Yeast
12
869-875
1996
841389
Galibert F.,Alexandraki D.,Baur A.,Boles E.,Chalwatzis N.,Chuat J.-C.,Coster F.,Cziepluch C.,de Haan M.,Domdey H.,Durand P.,Entian K.-D.,Gatius M.,Goffeau A.,Grivell L.A.,Hennemann A.,Herbert C.J.,Heumann K.,Hilger F.,Hollenberg C.P.,Huang M.-E.,Jacq C.,Jauniaux J.-C.,Katsoulou C.,Kirchrath L.,Kleine K.,Kordes E.,Koetter P.,Liebl S.,Louis E.J.,Manus V.,Mewes H.-W.,Miosga T.,Obermaier B.,Perea J.,Pohl T.M.,Portetelle D.,Pujol A.,Purnelle B.,Ramezani Rad M.,Rasmussen S.W.,Rose M.,Rossau R.,Schaaff-Gerstenschlaeger I.,Smits P.H.M.,Scarcez T.,Soriano N.,To Van D.,Tzermia M.,Van Broekhoven A.,Vandenbol M.,Wedler H.,von Wettstein D.,Wambutt R.,Zagulski M.,Zollner A.,Karpfinger-Hartl L.
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.
EMBO J.
15
2031-2049
1996
841390
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
841391
Hu Y.,Rolfs A.,Bhullar B.,Murthy T.V.S.,Zhu C.,Berger M.F.,Camargo A.A.,Kelley F.,McCarron S.,Jepson D.,Richardson A.,Raphael J.,Moreira D.,Taycher E.,Zuo D.,Mohr S.,Kane M.F.,Williamson J.,Simpson A.J.G.,Bulyk M.L.,Harlow E.,Marsischky G.,Kolodner R.D.,LaBaer J.
Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
Genome Res.
17
536-543
2007
841392
Yamashita S.,Oshima A.,Nikawa J.,Hosaka K.
Regulation of the phosphatidylethanolamine methylation pathway in Saccharomyces cerevisiae.
Eur. J. Biochem.
128
589-595
1982
841393
Greenberg M.L.,Reiner B.,Henry S.A.
Regulatory mutations of inositol biosynthesis in yeast: isolation of inositol-excreting mutants.
Genetics
100
19-33
1982
841394
Greenberg M.L.,Klig L.S.,Letts V.A.,Loewy B.S.,Henry S.A.
Yeast mutant defective in phosphatidylcholine synthesis.
J. Bacteriol.
153
791-799
1983
841395
Kodaki T.,Yamashita S.
Characterization of the methyltransferases in the yeast phosphatidylethanolamine methylation pathway by selective gene disruption.
Eur. J. Biochem.
185
243-251
1989
841396
McGraw P.,Henry S.A.
Mutations in the Saccharomyces cerevisiae opi3 gene: effects on phospholipid methylation, growth and cross-pathway regulation of inositol synthesis.
Genetics
122
317-330
1989
841397
Gaynor P.M.,Carman G.M.
Phosphatidylethanolamine methyltransferase and phospholipid methyltransferase activities from Saccharomyces cerevisiae. Enzymological and kinetic properties.
Biochim. Biophys. Acta
1045
156-163
1990
841398
Gaynor P.M.,Gill T.,Toutenhoofd S.,Summers E.F.,McGraw P.,Homann M.J.,Henry S.A.,Carman G.M.
Regulation of phosphatidylethanolamine methyltransferase and phospholipid methyltransferase by phospholipid precursors in Saccharomyces cerevisiae.
Biochim. Biophys. Acta
1090
326-332
1991
841399
Kodaki T.,Hosaka K.,Nikawa J.,Yamashita S.
Identification of the upstream activation sequences responsible for the expression and regulation of the PEM1 and PEM2 genes encoding the enzymes of the phosphatidylethanolamine methylation pathway in Saccharomyces cerevisiae.
J. Biochem.
109
276-287
1991
841400
Jackson J.C.,Lopes J.M.
The yeast UME6 gene is required for both negative and positive transcriptional regulation of phospholipid biosynthetic gene expression.
Nucleic Acids Res.
24
1322-1329
1996
841401
Huh W.-K.,Falvo J.V.,Gerke L.C.,Carroll A.S.,Howson R.W.,Weissman J.S.,O'Shea E.K.
Global analysis of protein localization in budding yeast.
Nature
425
686-691
2003
841402
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
841403
Sickmann A.,Reinders J.,Wagner Y.,Joppich C.,Zahedi R.P.,Meyer H.E.,Schoenfisch B.,Perschil I.,Chacinska A.,Guiard B.,Rehling P.,Pfanner N.,Meisinger C.
The proteome of Saccharomyces cerevisiae mitochondria.
Proc. Natl. Acad. Sci. U.S.A.
100
13207-13212
2003
841404
Bilgin M.,Markgraf D.F.,Duchoslav E.,Knudsen J.,Jensen O.N.,de Kroon A.I.,Ejsing C.S.
Quantitative profiling of PE, MMPE, DMPE, and PC lipid species by multiple precursor ion scanning: a tool for monitoring PE metabolism.
Biochim. Biophys. Acta
1811
1081-1089
2011
