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Sequence of NEOK_STRFR

EC Number:2.4.1.285

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
UDP-GlcNAc:ribostamycin N-acetylglucosaminyltransferase
Q53U11
Streptomyces fradiae
366
39257
Reaction
UDP-N-acetyl-alpha-D-glucosamine + ribostamycin = UDP + 2'''-acetyl-6'''-hydroxyneomycin C
Other sequences found for EC No. 2.4.1.285

General information:

Sequence
  0 MAEAPAGRAL FEIYDEGFDS PSWGGVETAL WHLSRSLREA GTEAEFYRSS EGADLDALAA
 60 RVERDRVDAV FPLVESDLFE GAAWRRLPAL HARTVRVWHD VSRLSADLSA PPPCPVHARV
120 PALPGAPVAE GCPARGAHPE GPMREVFLGE WPWTRCFPRR SVIPWAADHV PAKDLCDPSG
180 PVVLQLGKID TVDAERCLRR LTGAGVALRV VFATWSRRGR EARELVRAHQ GAGRRVEVLD
240 AYDIRTDWER VFGGASLFLL PSVFHETYNF AAAEAVQLGV PVAALGEGGN LPRFASLTAP
300 TPDALVDRLL AGGGAVAPRP RPAAGWRDVA ARYAEVIREH PAAGAGPAVP AGAGEGRGGR
360 EEEHGG
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
831120
Kudo F.,Yamamoto Y.,Yokoyama K.,Eguchi T.,Kakinuma K.
Biosynthesis of 2-deoxystreptamine by three crucial enzymes in Streptomyces fradiae NBRC 12773.
J. Antibiot.
58
766-774
2005
831121
Huang F.,Haydock S.F.,Mironenko T.,Spiteller D.,Li Y.,Spencer J.B.
The neomycin biosynthetic gene cluster of Streptomyces fradiae NCIMB 8233: characterisation of an aminotransferase involved in the formation of 2-deoxystreptamine.
Org. Biomol. Chem.
3
1410-1418
2005
831123
Yokoyama K.,Yamamoto Y.,Kudo F.,Eguchi T.
Involvement of two distinct N-acetylglucosaminyltransferases and a dual-function deacetylase in neomycin biosynthesis.
ChemBioChem
9
865-869
2008