Sequence of GATD_STRR6
EC Number:6.3.5.13
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
lipid II isoglutaminyl synthase (glutamine-hydrolysing)
Q8DNZ8
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
260
29193
Reaction
ATP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphospho-ditrans,octacis-undecaprenol + L-glutamine + H2O = ADP + phosphate + beta-D-GlcNAc-(1->4)-MurNAc-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala-diphospho-ditrans,octacis-undecaprenol + L-glutamate
Other sequences found for EC No. 6.3.5.13
General information:
Sequence
0 MVYTSLSSKD GNYPYQLNIA HLYGNLMNTY GDNGNILMLK YVAEKLGAHV TVDIVSLHDD
60 FDENHYDIAF FGGGQDFEQS IIADDLPAKK ESIDNYIQND GVVLAICGGF QLLGQYYVEA
120 SGKRIEGLGV MGHYTLNQTN NRFIGDIKIH NEDFDETYYG FENHQGRTFL SDDQKPLGQV
180 VYGNGNNEEK VGEGVHYKNV FGSYFHGPIL SRNANLAYRL VTTALKKKYG QDIQLPAYED
240 ILSQEIAEEY SDVKSKADFS
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
801895
Hoskins J.,Alborn W.E. Jr.,Arnold J.,Blaszczak L.C.,Burgett S.,DeHoff B.S.,Estrem S.T.,Fritz L.,Fu D.-J.,Fuller W.,Geringer C.,Gilmour R.,Glass J.S.,Khoja H.,Kraft A.R.,Lagace R.E.,LeBlanc D.J.,Lee L.N.,Lefkowitz E.J.,Lu J.,Matsushima P.,McAhren S.M.,McHenney M.,McLeaster K.,Mundy C.W.,Nicas T.I.,Norris F.H.,O'Gara M.,Peery R.B.,Robertson G.T.,Rockey P.,Sun P.-M.,Winkler M.E.,Yang Y.,Young-Bellido M.,Zhao G.,Zook C.A.,Baltz R.H.,Jaskunas S.R.,Rosteck P.R. Jr.,Skatrud P.L.,Glass J.I.
Genome of the bacterium Streptococcus pneumoniae strain R6.
J. Bacteriol.
183
5709-5717
2001
801896
Zapun A.,Philippe J.,Abrahams K.A.,Signor L.,Roper D.I.,Breukink E.,Vernet T.
In vitro reconstitution of peptidoglycan assembly from the Gram-positive pathogen Streptococcus pneumoniae.
ACS Chem. Biol.
8
2688-2696
2013
801897
Morlot C.,Straume D.,Peters K.,Hegnar O.A.,Simon N.,Villard A.M.,Contreras-Martel C.,Leisico F.,Breukink E.,Gravier-Pelletier C.,Le Corre L.,Vollmer W.,Pietrancosta N.,Havarstein L.S.,Zapun A.
Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae.
Nat. Commun.
9
3180-3180
2018
