Sequence of PANE_ECOLI
EC Number:1.1.1.169
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
(R)-pantoate + NADP+ = 2-dehydropantoate + NADPH + H+
Other sequences found for EC No. 1.1.1.169
General information:
Sequence
0 MKITVLGCGA LGQLWLTALC KQGHEVQGWL RVPQPYCSVN LVETDGSIFN ESLTANDPDF
60 LATSDLLLVT LKAWQVSDAV KSLASTLPVT TPILLIHNGM GTIEELQNIQ QPLLMGTTTH
120 AARRDGNVII HVANGITHIG PARQQDGDYS YLADILQTVL PDVAWHNNIR AELWRKLAVN
180 CVINPLTAIW NCPNGELRHH PQEIMQICEE VAAVIEREGH HTSAEDLRDY VMQVIDATAE
240 NISSMLQDIR ALRHTEIDYI NGFLLRRARA HGIAVPENTR LFEMVKRKES EYERIGTGLP
300 RPW
Download this sequence
in fasta formatDownload all sequences for 1.1.1.169
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
71873
Blattner F.R.,Plunkett G. III,Bloch C.A.,Perna N.T.,Burland V.,Riley M.,Collado-Vides J.,Glasner J.D.,Rode C.K.,Mayhew G.F.,Gregor J.,Davis N.W.,Kirkpatrick H.A.,Goeden M.A.,Rose D.J.,Mau B.,Shao Y.
The complete genome sequence of Escherichia coli K-12.
Science
277
1453-1462
1997
71874
Hayashi K.,Morooka N.,Yamamoto Y.,Fujita K.,Isono K.,Choi S.,Ohtsubo E.,Baba T.,Wanner B.L.,Mori H.,Horiuchi T.
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
Mol. Syst. Biol.
2
0-0
2006
71876
Zheng R.,Blanchard J.S.
Kinetic and mechanistic analysis of the E. coli panE-encoded ketopantoate reductase.
Biochemistry
39
3708-3717
2000
71877
Zheng R.,Blanchard J.S.
Identification of active site residues in E. coli ketopantoate reductase by mutagenesis and chemical rescue.
Biochemistry
39
16244-16251
2000
71878
Ciulli A.,Abell C.
Biophysical tools to monitor enzyme-ligand interactions of enzymes involved in vitamin biosynthesis.
Biochem. Soc. Trans.
33
767-771
2005
71879
Ciulli A.,Williams G.,Smith A.G.,Blundell T.L.,Abell C.
Probing hot spots at protein-ligand binding sites: a fragment-based approach using biophysical methods.
J. Med. Chem.
49
4992-5000
2006
71880
Matak-Vinkovic D.,Vinkovic M.,Saldanha S.A.,Ashurst J.L.,von Delft F.,Inoue T.,Miguel R.N.,Smith A.G.,Blundell T.L.,Abell C.
Crystal structure of Escherichia coli ketopantoate reductase at 1.7 A resolution and insight into the enzyme mechanism.
Biochemistry
40
14493-14500
2001
71881
Lobley C.M.C.,Ciulli A.,Whitney H.M.,Williams G.,Smith A.G.,Abell C.,Blundell T.L.
The crystal structure of Escherichia coli ketopantoate reductase with NADP+ bound.
Biochemistry
44
8930-8939
2005
71882
Ciulli A.,Lobley C.M.C.,Tuck K.L.,Smith A.G.,Blundell T.L.,Abell C.
pH-tuneable binding of 2'-phospho-ADP-ribose to ketopantoate reductase: a structural and calorimetric study.
Acta Crystallogr. D
63
171-178
2007
71883
Ciulli A.,Chirgadze D.Y.,Smith A.G.,Blundell T.L.,Abell C.
Crystal structure of Escherichia coli ketopantoate reductase in a ternary complex with NADP+ and pantoate bound: substrate recognition, conformational change, and cooperativity.
J. Biol. Chem.
282
8487-8497
2007
