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Sequence of SELT_HUMAN

EC Number:1.8.1.9

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
thioredoxin-disulfide reductase
P62341
Homo sapiens
195
22324
Reaction
thioredoxin + NADP+ = thioredoxin disulfide + NADPH + H+
Other sequences found for EC No. 1.8.1.9

General information:

Sequence
show sequence in fasta format
  0 MRLLLLLLVA ASAMVRSEAS ANLGGVPSKR LKMQYATGPL LKFQICVSUG YRRVFEEYMR
 60 VISQRYPDIR IEGENYLPQP IYRHIASFLS VFKLVLIGLI IVGKDPFAFF GMQAPSIWQW
120 GQENKVYACM MVFFLSNMIE NQCMSTGAFE ITLNDVPVWS KLESGHLPSM QQLVQILDNE
180 MKLNVHMDSI PHHRS
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
609887
Kryukov G.V.,Kryukov V.M.,Gladyshev V.N.
New mammalian selenocysteine-containing proteins identified with an algorithm that searches for selenocysteine insertion sequence elements.
J. Biol. Chem.
274
33888-33897
1999
609889
Clark H.F.,Gurney A.L.,Abaya E.,Baker K.,Baldwin D.T.,Brush J.,Chen J.,Chow B.,Chui C.,Crowley C.,Currell B.,Deuel B.,Dowd P.,Eaton D.,Foster J.S.,Grimaldi C.,Gu Q.,Hass P.E.,Heldens S.,Huang A.,Kim H.S.,Klimowski L.,Jin Y.,Johnson S.,Lee J.,Lewis L.,Liao D.,Mark M.R.,Robbie E.,Sanchez C.,Schoenfeld J.,Seshagiri S.,Simmons L.,Singh J.,Smith V.,Stinson J.,Vagts A.,Vandlen R.L.,Watanabe C.,Wieand D.,Woods K.,Xie M.-H.,Yansura D.G.,Yi S.,Yu G.,Yuan J.,Zhang M.,Zhang Z.,Goddard A.D.,Wood W.I.,Godowski P.J.,Gray A.M.
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Genome Res.
13
2265-2270
2003
609890
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
609891
Prevost G.,Arabo A.,Jian L.,Quelennec E.,Cartier D.,Hassan S.,Falluel-Morel A.,Tanguy Y.,Gargani S.,Lihrmann I.,Kerr-Conte J.,Lefebvre H.,Pattou F.,Anouar Y.
The PACAP-regulated gene selenoprotein T is abundantly expressed in mouse and human beta-cells and its targeted inactivation impairs glucose tolerance.
Endocrinology
154
3796-3806
2013
609892
Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
J. Proteomics
96
253-262
2014
609893
Boukhzar L.,Hamieh A.,Cartier D.,Tanguy Y.,Alsharif I.,Castex M.,Arabo A.,El Hajji S.,Bonnet J.J.,Errami M.,Falluel-Morel A.,Chagraoui A.,Lihrmann I.,Anouar Y.
Selenoprotein T exerts an essential oxidoreductase activity that protects dopaminergic neurons in mouse models of Parkinson's Disease.
Antioxid. Redox Signal.
24
557-574
2016
609894
Gladyshev V.N.,Arner E.S.,Berry M.J.,Brigelius-Flohe R.,Bruford E.A.,Burk R.F.,Carlson B.A.,Castellano S.,Chavatte L.,Conrad M.,Copeland P.R.,Diamond A.M.,Driscoll D.M.,Ferreiro A.,Flohe L.,Green F.R.,Guigo R.,Handy D.E.,Hatfield D.L.,Hesketh J.,Hoffmann P.R.,Holmgren A.,Hondal R.J.,Howard M.T.,Huang K.,Kim H.Y.,Kim I.Y.,Koehrle J.,Krol A.,Kryukov G.V.,Lee B.J.,Lee B.C.,Lei X.G.,Liu Q.,Lescure A.,Lobanov A.V.,Loscalzo J.,Maiorino M.,Mariotti M.,Sandeep Prabhu K.,Rayman M.P.,Rozovsky S.,Salinas G.,Schmidt E.E.,Schomburg L.,Schweizer U.,Simonovic M.,Sunde R.A.,Tsuji P.A.,Tweedie S.,Ursini F.,Whanger P.D.,Zhang Y.
Selenoprotein gene nomenclature.
J. Biol. Chem.
291
24036-24040
2016