Sequence of B8MLL4_TALSN
EC Number:2.3.1.161
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
lovastatin nonaketide synthase
B8MLL4
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2434
267301
Reaction
9 malonyl-CoA + 11 NADPH + 10 H+ + S-adenosyl-L-methionine + holo-[lovastatin nonaketide synthase] = dihydromonacolin L-[lovastatin nonaketide synthase] + 9 CoA + 9 CO2 + 11 NADP+ + S-adenosyl-L-homocysteine + 6 H2O
Other sequences found for EC No. 2.3.1.161
General information:
Sequence
0 MSTSSTLQTP STSVTGGSEF DDIAVIGLAC RFPGGASDAE KFWELLYNKR SAFCRAPHTR
60 YNVDAFHNSS RNRLNTLSAL GGHFLEEDVA AFDAPFFNIT AEEAKAMDPT ARMLLEVTYE
120 ALENAGLPIE NLTGSDTSCY VGCFTRDYHE MLMRDAETSP MYAGTGTGFS LLSNRVSWFY
180 DLRGPSMTLD TACSSSLVGM HLACQGLRSK ESRIAVVCGA NLILSPDLGM WLSNLKMTSI
240 DGLSRSFADG VTGYGRGEGI ATVILKPLAD ALKDGDAIRA VIRGTGVNQD GHTTGITLPN
300 SEAQADLIRA TYRAAGLDFS QTSYFEAHGT GTEAGDPLEL GAVARTISQT RRSEDKLYVG
360 SVKSNIGHLE GAAGLAGVIK CILMLEKGAI LPNIHFDRPS KRIPFDSWNI QVPTDIVPWP
420 QNRLKRASVN SFGYGGTNAH TILDDAEQFL SGYQDWQLVE RQVAADERER LFVFSAPDES
480 ALRRMIQRFD DYLSIKTSIA ELQNAPERNI FLDKLSFTLS NRRSRFSWKA SATATTIPEL
540 QEALSITNSA LIKRTPDSAR LAFVFTGQGA QWAKMGMELM SYTVFSDSVH EADNYLRTHL
600 GSEWSVITEL QRDKEDSNVH LAKISQPVCT VLQIALVELL KSWNIQPSGV VGHSSGEIAA
660 AYCYGALSRE DAWSVAYWRG KICSELNKDA PHLKGAMMAV GLSSEVAEEY IGKVKGKIVV
720 ACINSPSSVT ISGDESGIDE LQKLLSTDAV FCRKLVVENA YHSHHMELIA EKYLQKISTI
780 STSEAATKDN EVKMASSVTG ELIRSAAELG PAYWVKNFVS PVRFAEAVAV ILKDSNTRRR
840 RRARAGESAF DLLLEVGPHG ALKGPLRQIL RHHDISTVTY TSLLNRGEKA TKSTLYATGE
900 LYIHGVPVSI SAVNKQASQT PPPTPLVDLP TYAWNHSLRY WAESRLSKSY RFRKYPRHDL
960 LGAPVADFND REPRWRNILR ANEQPWVRDH VVYSSILYPG SGMITMVLEA VRQLAQERQG
1020 KGIESIKLEN VRIGKAIVIP DDQTGVETLL QLRSQESELS SHASYEAWDF TVSSCHEDSK
1080 LEENSSGTVT VRYSGNSQGV ISQNTGKSLI SQVARQEYNT AKLSCTQSIN PVDFYDATQA
1140 AGLKYGPSFQ GLTEITAGSD RSVGIIKIPD WRKYHNVQGS SHLIHPTTLD IIFHSMFAAI
1200 VEKSNKGEGK VDFKTAAVPI AFDSLIFYLD NFPPSSPSLD KSAQFSTCCR VIRNADQRDL
1260 VADIYVSDLA WQEPKIVVQG IRCRELPGKD AGTSKGQVKA PLGTLKWKPD IDFMGEVPVR
1320 QYIAKFLSTR EDLPRNYLEN DSSVEKWEKE VSAIADLAAH KNPYLSILQV GKSDSLTRSV
1380 FSALSAHDPS NPSLANYIII DGDSEAIAHS QSTFQNSSDL ITFYTGDIES GRQSGNLKDD
1440 AFDLVIAVSD LSSADEIDHA MECLHDRGSL VLNETNQEKA SGFLSINHVK SLPNTSILNC
1500 FSDANHYLAR KLGPTYSFED NAIFIIEPKD RTTEVLEVSH LLSTKLTNHG LQVKTVQWSS
1560 ANMSDFHGKY LISLLELETS FLSNISEDDY LILKTIALNS SRLLWVSRGT DPAMQAPVGY
1620 LRTLQNENVN LDLRYLLLEG RANRLADEIA STLAELALAP TTDREYMEID GNLCINRWLV
1680 DKRLKHFMTS SGEQHGGSTE LVALREIGIS TLKLHHISDK ESKLVWFTVD HESQQRELSA
1740 DEVEVHVKAV GLKSFLQSHD DTVNSNIKSV KEFSGIVTNV GNSCSRLKDG DRVWTCALTD
1800 SYKISFRVKE SLCQVIPNSV SFEDAASWAV THSTAYQTVV QMAKIQPGHR ILIQSAANGI
1860 GQITIQIALR RGAQVYATVN SKEQSDVVKS MGVPRENILG DNDLDLAAAI SQLTHGKGLD
1920 VIINQTSTRK SIQQLWNSVA AFGMLIDISN PETTPDEQPA LAMTPFHRGA SYRLFNLAKL
1980 FEENPSSMEI ILQDVLQFGP HRQNIQRPTP WKVFSATTVD EAFDWTSSHG HEGKGILTFG
2040 PDDSIFVDRR ALNPLTLDSN YTYLLAGGLG GLGKSLAKLL AQNGARHLAF VSRSGPASKN
2100 AVSLTQELAA MGVKSAIYAG NISDQSAVAD ILVQCAAEMP PIRGVIQSAA VLEDFIYDNM
2160 TYKQWVDATR PKIQGSWLLH HLLLEAKNDL QFFVMLSSIA GVVGNRSQAN YAAGNTYQDA
2220 LANYRRQRGL PAVSVDLGLM LGIGLIAEER GGTTNLKKWE AVGINEQEFH AIMTAAIAEN
2280 KSLPAQVICG LPTGGILQSE DLDRPFYFDD PRFSFLRKKD VDETLNKQDG DDAADSPSFQ
2340 LSRAESMRDA IDIITTAVCQ RLARGLQTAA ENIDANKPLH SYGVDSLMAV EIRTWITANL
2400 QADISLFDIL SGVSVAALAA KIAVKSKVLP DGIN
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
8625882
Nierman W.C.,Fedorova-Abrams N.D.,Andrianopoulos A.
Genome sequence of the AIDS-associated pathogen Penicillium marneffei (ATCC18224) and its near taxonomic relative Talaromyces stipitatus (ATCC10500).
Genome Announc.
3
0-0
2015
