Sequence of KDM4_CAEEL
EC Number:1.14.11.66
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
a [histone H3]-N6,N6,N6-trimethyl-L-lysine9 + 2 2-oxoglutarate + 2 O2 = a [histone H3]-N6-methyl-L-lysine9 + 2 succinate + 2 formaldehyde + 2 CO2
Other sequences found for EC No. 1.14.11.66
General information:
Sequence
0 MASAATTTHF PSSRIPSEPC ASSGPLFPDD VLFTTEASSA SSSSCHVEND SRPLSPTMFT
60 DGRTPVNISA KHLKDHPLHE PTGTSEVLTF YPTMREFKNF SQYIKKIEQN GGHLKAGIAK
120 IVAPEGWTPR PTRKDFSDVD DYEITQPARE TIEATEKPGA YFKRNVTCRR KMPVREFRTL
180 ANSAQYRNPR PDLKGSEIEK HYFDNILHGE PIYGADTEGS FYDAQVEEWN MNRLGTILED
240 TNYEIKGVNT VYLYFGMYKT TFPWHAEDMD LYSINFLHFG APKYWFAISS EHADRFERFM
300 SQQFSYQNEY APQCKAFLRH KTYLVTPELL RQAGIPYATM VQRPNEFIIT FPRGYHMGFN
360 LGYNLAESTN FASQRWIDYG KDAVLCDCNK DSVKIDMTHF MAKYRPDEYT TWWTYWYGGG
420 RELWIPKKKK EVPKKRRQSL ADASKIAKRA RLGASSTATD SDGSSGSSGS EEATEGSSFM
480 RALPAGYTVH NWQLRPDYDE LLRKYKKETK LLRSDTRIDF YQEREFNHAR RAEWPHCAVC
540 QYFQPPHMNA INHTVPNSSR RLIPKWCFSK TDTKKHEDHH EPPPPLDRLL TCSNCHVTVH
600 SHCCSGGGGG GGDDDDVTSS GEPWRCPRCR NRTDVEIRTT SCQLCELRGG ALIPCQIGTD
660 STWAHVACAL FNRRAIFDCP NRPGACFVEP SPRQQSETPR MPPRRLSEEY RAELGDLYEN
720 SRWECVVCHR TDEGLAPCVL CIEEQATTSL PTLAHVTCAR RVGFVCEVRD YPRGVVMICH
780 KHEHSYLVNK TTQQQAYTNV KVGDFVFVED VVEPPQKLFT RGAIVRADKK ETVVVDFLDN
840 SCSRDNHVED IISCECLFCE NGDHQYGARV KVVWDDKQVY DAYFRGKGQM IEYTVRLEDG
900 REVRHPRNRL KTKRELNAYL KK
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
561431
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science
282
2012-2018
1998
561432
Whetstine J.R.,Nottke A.,Lan F.,Huarte M.,Smolikov S.,Chen Z.,Spooner E.,Li E.,Zhang G.,Colaiacovo M.,Shi Y.
Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.
Cell
125
467-481
2006
561433
Ni Z.,Ebata A.,Alipanahiramandi E.,Lee S.S.
Two SET domain containing genes link epigenetic changes and aging in Caenorhabditis elegans.
Aging Cell
11
315-325
2012
561434
Greer E.L.,Beese-Sims S.E.,Brookes E.,Spadafora R.,Zhu Y.,Rothbart S.B.,Aristizabal-Corrales D.,Chen S.,Badeaux A.I.,Jin Q.,Wang W.,Strahl B.D.,Colaiacovo M.P.,Shi Y.
A histone methylation network regulates transgenerational epigenetic memory in C. elegans.
Cell Rep.
7
113-126
2014
