EC Number |
Protein Variants |
Reference |
---|
4.2.1.159 | E139Q |
complete loss of catalytic activity |
-, 733338 |
4.2.1.159 | E190A |
complete loss of catalytic activity |
-, 733338 |
4.2.1.159 | E190Q |
complete loss of catalytic activity |
-, 733338 |
4.2.1.159 | E231A/E233A |
mutant constructed to reduce surface entropy. None of the resulting crystals demonstrates improved diffraction properties |
733338 |
4.2.1.159 | E316A/K317A |
mutant constructed to reduce surface entropy. None of the resulting crystals demonstrates improved diffraction properties |
733338 |
4.2.1.159 | E405 |
complete loss of catalytic activity |
733338 |
4.2.1.159 | E405A |
complete loss of catalytic activity |
-, 733338 |
4.2.1.159 | K289A/Q290A/E293A |
mutant constructed to reduce surface entropy. None of the resulting crystals demonstrates improved diffraction properties |
733338 |
4.2.1.159 | R381A |
mutant with improved crystallization parameters, kinetic parameters similar to wild-type |
-, 733338 |