EC Number   |
Protein Variants |
Reference |
|---|
   3.6.5.2 | A152P |
mutation dramatically affects both GTP and GDP nucleotide-binding activity of Rab27a, probably by disrupting protein folding |
658342 |
| 3.6.5.2 | AS28N |
the mutant significantly inhibits KCl-induced insulin secretion but has no significant effect on glucose/carbachol-and glucose/KCl-induced insulin secretion despite an inhibitory trend |
698766 |
| 3.6.5.2 | C192S |
FgCDC42 cDNA is amplified from cDNA of PH-1 with a site mutation C192S to ensure that FgCdc42 protein cannot be prenylated and is soluble |
-, 733922 |
| 3.6.5.2 | C196S |
FgRAC1 cDNA is amplified from cDNA of PH-1 with a site mutation C196S to ensure that FgRac1 protein cannot be prenylated and is soluble |
-, 733922 |
| 3.6.5.2 | C32S/Q68L |
design OsRac1 mutants that display reduced binding to the NADPH oxidase OsRbohB. Tyr39 and Asp45 substitutions suppress ROS production in rice cells, these residues are critical for interaction with and activation of NADPH oxidase OsRbohB |
734276 |
| 3.6.5.2 | chimeras between RhoA/Cdc42 |
residues 85-122 contain specific binding determinants for guanosine nucleotide activating protein, p190 |
644130 |
| 3.6.5.2 | D124N |
Ypt1, changed nucleotide specificity from guanine to xanthine, complete inhibition of guanosine nucleotide exchange factor-mediated nucleotide exchange |
644131 |
| 3.6.5.2 | D57N |
the dominant negative Rac GTPase mutation does not only inhibit Rac1, Rac2, and Rac3 activities, but may also inhibit Cdc42 |
699993 |
| 3.6.5.2 | D60I |
site-directed mutagenesis |
733638 |
| 3.6.5.2 | D60K |
site-directed mutagenesis |
733638 |
