EC Number |
Protein Variants |
Reference |
---|
2.4.1.355 | D178N |
severe decrease in activity |
746274 |
2.4.1.355 | D91A |
active-site mutant, complete loss of activity |
746274 |
2.4.1.355 | D93A |
active-site mutant, complete loss of activity |
-, 746274 |
2.4.1.355 | D94A |
active-site mutant, complete loss of activity |
-, 746274 |
2.4.1.355 | E177A |
active-site mutant, complete loss of activity |
746274 |
2.4.1.355 | H210A |
active-site mutant, complete loss of activity |
-, 746274 |
2.4.1.355 | M521R |
structure-guided mutant, aimed at disrupting the trimerization interface. Mutation results in the expression of insoluble protein aggregates |
746274 |
2.4.1.355 | M532R |
structure-guided mutant, aimed at disrupting the trimerization interface. Mutation results in the expression of insoluble protein aggregates |
746274 |
2.4.1.355 | R206A |
severe decrease in activity |
746274 |
2.4.1.355 | R75A |
active-site mutant, complete loss of activity |
-, 746274 |