EC Number |
Protein Variants |
Reference |
---|
1.3.1.22 | A207D |
the mutation is associated with 5alpha-reductase type 2 deficiency |
687319 |
1.3.1.22 | A248V |
somatic variant, reduction of the apparent Ki for both finasteride and dutasteride |
675475 |
1.3.1.22 | A49T |
constitutional and somatic variant, time-independent inhibition, more than 100fold lower apparent Ki for dutasteride than for finasteride |
675475 |
1.3.1.22 | A49T |
the mutation is associated with 5alpha-reductase type 2 deficiency |
687319 |
1.3.1.22 | A51T |
constitutional variant, reduction of the apparent Ki for both finasteride and dutasteride |
675475 |
1.3.1.22 | C133G |
the mutation is associated with 5alpha-reductase type 2 deficiency |
687319 |
1.3.1.22 | C5R |
constitutional variant, reduction of the apparent Ki for both finasteride and dutasteride |
675475 |
1.3.1.22 | F118L |
somatic variant, no significant change of the apparent Ki for both finasteride and dutasteride |
675475 |
1.3.1.22 | F194L |
constitutional variant, time-independent inhibition, displays lower apparent Ki for finasteride than dutasteride |
675475 |
1.3.1.22 | F234L |
constitutional variant, reduction of the apparent Ki for finasteride but not for dutasteride |
675475 |