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1.1.1.366
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identification of a gene cluster encoding NADPH-dependent, L-idonate forming, 2-keto-L-gulonate reductase and NAD+-dependent L-idonate 5-dehydrogenase which forms 5-keto-D-gluconate. These genes are involved in the fungal D-glcUA catabolism and the reaction catalyzed by the latter enzyme is a direct continuation for the previously identified reaction by the action of GluC. Generation of a gene gluE deletion mutant strain, phenotype, overview. The gluE deletion in Aspergillus niger causes a phenotype with reduced growth and ceased D-glcUA consumption
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