EC Number   |
Protein Variants |
Reference  |
|---|
   3.4.21.47 | D715A |
factor B mutation, severly reduces hemolytic activity, in complex with C3b no cleavage of C3 |
36600 |
| 3.4.21.47 | D715E |
factor B mutation, severly reduces hemolytic activity, in complex with C3b no cleavage of C3 |
36600 |
| 3.4.21.47 | D715N |
factor B mutation, severly reduces hemolytic activity, in complex with C3b no cleavage of C3 |
36600 |
| 3.4.21.47 | D715S |
factor B mutation, severly reduces hemolytic activity |
36600 |
| 3.4.21.47 | D715Y |
factor B mutation, severly reduces hemolytic activity |
36600 |
| 3.4.21.47 | F716A |
factor B mutation, severly reduces hemolytic activity |
36600 |
| 3.4.21.47 | D254G |
mutation in the Bb component decreases sensitivity to DAF to 9% of the wild-type value, sensitivity to CR1 to 4% of the wild-type value and sensitivity to Factor H to 48% of the wild-type value |
652225 |
| 3.4.21.47 | D382A |
mutation in the Bb component decreases sensitivity to DAF to 36% of the wild-type value, sensitivity to CR1 to 41% of the wild-type value |
652225 |
| 3.4.21.47 | D382N |
mutation in the Bb component decreases sensitivity to DAF to 54% of the wild-type value |
652225 |
| 3.4.21.47 | D445A |
mutation in the Bb component decreases sensitivity to CR1 to 71% of the wild-type value |
652225 |
