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EC Number Protein Variants Commentary Reference
Show all pathways known for 5.1.2.2Display the word mapDisplay the reaction diagram Show all sequences 5.1.2.2Y54L site-directed mutagenesis 726974
Show all pathways known for 5.1.2.2Display the word mapDisplay the reaction diagram Show all sequences 5.1.2.2Y54Q compared to wild-type enzyme the catalytic preference of the mutant enzyme is reversed and catalytic efficiency is reduced. Mutant enzyme exhibits higher affinity for (R)-mandelate than for (S)-mandelate, and a higher turnover number with (S)-mandelate as the substrate, relative to that with (R)-mandelate 661212
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