EC Number   |
Protein Variants |
Reference |
|---|
    2.4.1.129 | F104A |
site-directed mutagenesis, the binding response for F104A is drastically decreased compared to the wild-type |
735646 |
| 2.4.1.129 | F120S |
site-directed mutagenesis, modification of the residue within the hydrophobic region of enzyme MtgA yields monodisperse forms of the protein with apparently no change in its secondary structure content, but at the expense of the enzyme function. Mutation F120S may affect the outer helix transition/conformational change during catalysis |
735646 |
| 2.4.1.129 | F150S |
site-directed mutagenesis, insoluble mutant |
735646 |
| 2.4.1.129 | F158S |
site-directed mutagenesis |
735646 |
| 2.4.1.129 | F237A |
mutant with completely abolished activity |
704438 |
| 2.4.1.129 | F237A |
no activity in vitro |
704438 |
| 2.4.1.129 | G242A |
the mutant shows 4% of wild type activity |
704438 |
| 2.4.1.129 | G264L |
no activity in vitro |
704438 |
| 2.4.1.129 | G494E |
naturally occuring mutation, the mutant cannot be transformed with a DELTApbp2a deletion and shows the small-cell phenotype characteristic of DELTApbp1a mutants, reduced activity compared to wild-type |
-, 759785 |
| 2.4.1.129 | H240A |
mutant with completely abolished activity |
704438 |
