EC Number   |
Protein Variants |
Reference  |
|---|
    1.1.1.87 | K206M |
site-directed mutagenesis, inactive mutant |
739958 |
| 1.1.1.87 | Y150F |
site-directed mutagenesis, inactive mutant |
739958 |
| 1.1.1.87 | I82N |
the mutant shows decreased catalytic efficiency with homoisocitrate and isocitrate compared to the wild type enzyme and has no activity with 3-isopropylmalate |
-, 760522 |
| 1.1.1.87 | L81P |
the mutant shows decreased catalytic efficiency with homoisocitrate, isocitrate and 3-isopropylmalate compared to the wild type enzyme |
-, 760522 |
| 1.1.1.87 | L83R |
the mutant shows decreased catalytic efficiency with homoisocitrate and isocitrate compared to the wild type enzyme and has no activity with 3-isopropylmalate |
-, 760522 |
| 1.1.1.87 | S80A |
the mutant shows decreased catalytic efficiency with homoisocitrate, isocitrate and 3-isopropylmalate compared to the wild type enzyme |
-, 760522 |
| 1.1.1.87 | T71V |
the mutant shows decreased catalytic efficiency with homoisocitrate and isocitrate, as well as increased catalytic efficiency with 3-isopropylmalate compared to the wild type enzyme |
-, 760522 |
