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<< < Results 101 - 110 of 110
EC Number
Protein Variants
Commentary
Reference
R266Q
a naturally occuirng missense mutation the epimerase part of the bifunctional enzyme
R266W
a naturally occuirng missense mutation the epimerase part of the bifunctional enzyme
R277C
a naturally occuirng missense mutation the epimerase part of the bifunctional enzyme
R306Q
a naturally occuirng missense mutation the epimerase part of the bifunctional enzyme
R335W
a naturally occuirng missense mutation the epimerase part of the bifunctional enzyme
V216A
a naturally occuirng missense mutation the epimerase part of the bifunctional enzyme
V331A
a naturally occuirng missense mutation the epimerase part of the bifunctional enzyme
V367I
a naturally occuirng missense mutation the epimerase part of the bifunctional enzyme
D378Y
60% reduction of epimerase activity
H213N
30fold increase in Km-value and 50fold decrease in turnover-number for UDP-N-acetyl-D-glucosamine. Unlike the wild-type enzyme no inhibition is detected at UDP-concentrations up to 10 mM
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