EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
1.5.3.16 | Adenocarcinoma |
12827295 |
Induction of the PAOh1/SMO polyamine oxidase by polyamine analogues in human lung carcinoma cells. |
causal interaction diagnostic usage ongoing research therapeutic application |
3 1 4 1 |
1.5.3.16 | Brain Infarction |
27037020 |
Aggravation of brain infarction through an increase in acrolein production and a decrease in glutathione with aging. |
unassigned |
0 |
1.5.3.16 | Brain Injuries |
26530396 |
Astrocyte-Dependent Vulnerability to Excitotoxicity in Spermine Oxidase-Overexpressing Mouse. |
causal interaction unassigned |
1 0 |
1.5.3.16 | Breast Neoplasms |
16207710 |
Spermine oxidase SMO(PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines. |
causal interaction diagnostic usage ongoing research unassigned |
4 1 3 0 |
1.5.3.16 | Breast Neoplasms |
20946629 |
Spermine oxidase (SMO) activity in breast tumor tissues and biochemical analysis of the anticancer spermine analogues BENSpm and CPENSpm. |
therapeutic application unassigned |
1 0 |
1.5.3.16 | Carcinogenesis |
17145855 |
Tumor necrosis factor-alpha increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: a potential mechanism for inflammation-induced carcinogenesis. |
ongoing research unassigned |
3 0 |
1.5.3.16 | Carcinogenesis |
18302221 |
Increased spermine oxidase expression in human prostate cancer and prostatic intraepithelial neoplasia tissues. |
causal interaction diagnostic usage ongoing research unassigned |
4 3 3 0 |
1.5.3.16 | Carcinogenesis |
18422650 |
Nuclear localization of human spermine oxidase isoforms - possible implications in drug response and disease etiology. |
causal interaction therapeutic application unassigned |
4 3 0 |
1.5.3.16 | Carcinogenesis |
27041578 |
Epigenetic silencing of miR-124 prevents spermine oxidase regulation: implications for Helicobacter pylori-induced gastric cancer. |
causal interaction therapeutic application unassigned |
4 1 0 |
1.5.3.16 | Carcinogenesis |
32863742 |
The Mechanism of Bacteroides fragilis Toxin Contributes to Colon Cancer Formation. |
causal interaction diagnostic usage ongoing research unassigned |
1 2 1 0 |