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EC Number
Disease
PubMed ID
Title of Publication
Category
Confidence Level
Abortion, Septic
Umbilical cord 'pseudo-vasculitis' following second trimester fetal death: a clinicopathological and immunohistochemical study of 13 cases.
diagnostic usage
ongoing research
unassigned
3
2
0
Abortion, Spontaneous
[Human placental myeloperoxidase in miscarriage]
diagnostic usage
ongoing research
unassigned
1
4
0
Abscess
Partial characterization of a bactericidal system in staphylococcal abscesses.
diagnostic usage
ongoing research
unassigned
1
2
0
Abscess
Differential excretion of leucocyte granule components in inflammatory bowel disease: implications for pathogenesis.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
2
1
0
Abscess
Low-dose curcumin reduced TNBS-associated mucin depleted foci in mice by scavenging superoxide anion and lipid peroxides, rebalancing matrix NO synthase and aconitase activities, and recoupling mitochondria.
unassigned
0
Acatalasia
Catalase deficiency in myeloperoxidase deficient polymorphonuclear leucocytes from chicken.
diagnostic usage
ongoing research
therapeutic application
unassigned
2
1
1
0
Acidosis
Treatment of burned mice with hyperbaric oxygen reduces mesenteric bacteria but not pulmonary neutrophil deposition.
causal interaction
therapeutic application
unassigned
4
2
0
Acidosis
The role of endogenous nitric oxide and platelet-activating factor in hypoxia-induced intestinal injury in rats.
unassigned
0
Acidosis
Urethan anesthesia protects rats against lethal endotoxemia and reduces TNF-alpha release.
therapeutic application
unassigned
1
0
Acidosis
Acidosis stimulates nitric oxide production and lung damage in rats.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
4
1
0
Acidosis
Extracellular acidification induces human neutrophil activation.
unassigned
0
Acidosis, Lactic
Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on haemodynamics or regional microvascular flow.
causal interaction
unassigned
4
0
Acne Vulgaris
Superoxide dismutase and myeloperoxidase activities in polymorphonuclear leukocytes in acne vulgaris.
causal interaction
ongoing research
unassigned
2
2
0
Acquired Immunodeficiency Syndrome
Disseminated tubuloreticular inclusions in acquired immunodeficiency syndrome (AIDS).
diagnostic usage
ongoing research
unassigned
4
4
0
Acquired Immunodeficiency Syndrome
Myeloperoxidase aids prognostication together with N-terminal pro-B-type natriuretic peptide in high-risk patients with acute ST elevation myocardial infarction.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
2
1
0
Acquired Immunodeficiency Syndrome
Methods for measuring myeloperoxidase activity toward assessing inhibitor efficacy in living systems.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
2
4
0
Acquired Immunodeficiency Syndrome
Discrepancies between two immunoassays for the determination of MPO and PR3 autoantibodies.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
3
1
0
Acute Coronary Syndrome
Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes.
causal interaction
ongoing research
unassigned
1
3
0
Acute Coronary Syndrome
Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
4
1
0
Acute Coronary Syndrome
Identification of alpha-chloro fatty aldehydes and unsaturated lysophosphatidylcholine molecular species in human atherosclerotic lesions.
causal interaction
therapeutic application
unassigned
4
2
0
Acute Coronary Syndrome
[Acute coronary syndrome and inflammation. Biomarkers for diagnostics and risk stratification]
causal interaction
diagnostic usage
unassigned
2
3
0
Acute Coronary Syndrome
The effect of atorvastatin on serum myeloperoxidase and CRP levels in patients with acute coronary syndrome.
diagnostic usage
ongoing research
unassigned
4
2
0
Acute Coronary Syndrome
[Changes of neutrophil myeloperoxidase in coronary circulation among patients with acute coronary syndrome]
causal interaction
diagnostic usage
ongoing research
unassigned
4
4
3
0
Acute Coronary Syndrome
Multimarker panel to rule out acute coronary syndromes in low-risk patients.
diagnostic usage
therapeutic application
unassigned
3
1
0
Acute Coronary Syndrome
[Myeloperoxidase in the plasma of patients with acute coronary syndrome]
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
4
4
1
Acute Coronary Syndrome
Usefulness of baseline plasma myeloperoxidase levels as an independent predictor of myocardial infarction at two years in patients presenting with acute coronary syndrome.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
4
1
0
Acute Coronary Syndrome
Appraisal of myeloperoxidase for evaluation of patients with suspected acute coronary syndromes.
diagnostic usage
therapeutic application
unassigned
3
2
0
Acute Coronary Syndrome
[Clinical implications of relationship between myeloperoxidase and acute coronary syndromes]
causal interaction
diagnostic usage
ongoing research
unassigned
4
4
4
0
Acute Coronary Syndrome
Myeloperoxidase level in patients with stable coronary artery disease and acute coronary syndromes.
causal interaction
diagnostic usage
ongoing research
unassigned
4
4
2
0
Acute Coronary Syndrome
Concurrent evaluation of novel cardiac biomarkers in acute coronary syndrome: myeloperoxidase and soluble CD40 ligand and the risk of recurrent ischaemic events in TACTICS-TIMI 18.
diagnostic usage
ongoing research
unassigned
3
1
0
Acute Coronary Syndrome
Myeloperoxidase: a new biomarker of inflammation in ischemic heart disease and acute coronary syndromes.
causal interaction
diagnostic usage
unassigned
4
3
0
Acute Coronary Syndrome
Plasma levels of myeloperoxidase are not elevated in patients with stable coronary artery disease.
causal interaction
diagnostic usage
unassigned
4
4
0
Acute Coronary Syndrome
Up-and-coming markers: myeloperoxidase, a novel biomarker test for heart failure and acute coronary syndrome application?
causal interaction
diagnostic usage
therapeutic application
unassigned
4
3
1
0
Acute Coronary Syndrome
Lack of diagnostic and prognostic utility of circulating plasma myeloperoxidase concentrations in patients presenting with dyspnea.
causal interaction
diagnostic usage
ongoing research
unassigned
4
4
2
0
Acute Coronary Syndrome
C-reactive protein stimulates myeloperoxidase release from polymorphonuclear cells and monocytes: implications for acute coronary syndromes.
ongoing research
unassigned
3
0
Acute Coronary Syndrome
Diurnal variation of circulating myeloperoxidase levels in patients with ST-segment elevation myocardial infarction.
causal interaction
therapeutic application
unassigned
4
1
0
Acute Coronary Syndrome
Myeloperoxidase (MPO) and interleukin-17 (IL-17) plasma levels are increased in patients with acute coronary syndromes.
causal interaction
diagnostic usage
unassigned
4
3
0
Acute Coronary Syndrome
Role of myeloperoxidase as predictor of systemic inflammatory response syndrome in patients with ST-segment elevation myocardial infarction after primary percutaneous coronary intervention.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
4
2
0
Acute Coronary Syndrome
Coronary stenting is associated with an acute increase in plasma myeloperoxidase in stable angina patients but not in patients with acute myocardial infarction.
causal interaction
diagnostic usage
ongoing research
unassigned
4
4
2
0
Acute Coronary Syndrome
Serial Analyses of C-Reactive Protein and Myeloperoxidase in Acute Coronary Syndrome.
causal interaction
diagnostic usage
unassigned
3
3
0
Acute Coronary Syndrome
Myeloperoxidase is not useful for the early assessment of patients with chest pain.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
4
2
0
Acute Coronary Syndrome
No relationship between neutrophil granulocyte activation and the myeloperoxidase gene - 129 G>A and - 463 G>A promoter polymorphisms: implications for investigations of cardiovascular disease.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
4
1
0
Acute Coronary Syndrome
Prognostic value of myeloperoxidase in coronary artery disease: comparison of unstable and stable angina patients.
causal interaction
diagnostic usage
ongoing research
unassigned
4
4
1
0
Acute Coronary Syndrome
Factors influencing local and systemic levels of plasma myeloperoxidase in ST-segment elevation acute myocardial infarction.
causal interaction
diagnostic usage
unassigned
4
3
0
Acute Coronary Syndrome
Lack of association between plasma myeloperoxidase levels and angiographic severity of coronary artery disease in patients with acute coronary syndrome.
causal interaction
diagnostic usage
ongoing research
unassigned
4
4
2
0
Acute Coronary Syndrome
Plasma myeloperoxidase predicts incident cardiovascular risks in stable patients undergoing medical management for coronary artery disease.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
3
1
3
Acute Coronary Syndrome
High levels of systemic myeloperoxidase are associated with coronary plaque erosion in patients with acute coronary syndromes: a clinicopathological study.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
4
1
0
Acute Coronary Syndrome
Diagnostic efficacy of myeloperoxidase for the detection of acute coronary syndromes.
diagnostic usage
therapeutic application
unassigned
4
3
0
Acute Coronary Syndrome
Myeloperoxidase improves risk stratification in patients with ischemia and normal cardiac troponin I concentrations.
causal interaction
diagnostic usage
therapeutic application
unassigned
3
3
2
0
Acute Coronary Syndrome
Myeloperoxidase in the acute coronary syndrome: Equal concentrations at any time of day?
causal interaction
unassigned
1
0
Acute Coronary Syndrome
Multimarker risk model containing troponin-T, interleukin 10, myeloperoxidase and placental growth factor predicts long-term cardiovascular risk after non-ST-segment elevation acute coronary syndrome.
diagnostic usage
unassigned
3
0
Acute Coronary Syndrome
Relationship between cardiovascular risk factors and biomarkers with necrotic core and atheroma size: a serial intravascular ultrasound radiofrequency data analysis.
diagnostic usage
unassigned
3
0
Acute Coronary Syndrome
Letter by schindhelm regarding article, "high levels of systemic myeloperoxidase are associated with coronary plaque erosion in patients with acute coronary syndromes: a clinicopathological study".
causal interaction
diagnostic usage
unassigned
3
1
0
Acute Coronary Syndrome
Long-term Prognostic Value of Myeloperoxidase on Acute Coronary Syndrome-A Meta-analysis.
causal interaction
unassigned
4
0
Acute Coronary Syndrome
[Metabolic activity of neutrocytes and possible ways of its correction in patients with an acute coronal syndrome].
diagnostic usage
ongoing research
unassigned
3
4
0
Acute Coronary Syndrome
Heart fatty acid-binding protein offers similar diagnostic performance to high-sensitivity troponin T in emergency room patients presenting with chest pain.
diagnostic usage
ongoing research
unassigned
4
2
0
Acute Coronary Syndrome
Risk prediction with serial myeloperoxidase monitoring in patients with acute chest pain.
causal interaction
diagnostic usage
unassigned
3
3
0
Acute Coronary Syndrome
Response: myeloperoxidase as a biomarker in acute coronary syndrome: a trap or a treasure.
causal interaction
therapeutic application
unassigned
1
3
0
Acute Coronary Syndrome
Myeloperoxidase as a biomarker in acute coronary syndrome: beware of the pitfalls.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
1
1
0
Acute Coronary Syndrome
Myeloperoxidase in the diagnosis of acute coronary syndromes: the importance of spectrum.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
4
1
0
Acute Coronary Syndrome
Myeloperoxidase may help to differentiate coronary plaque erosion from plaque rupture in patients with acute coronary syndromes.
causal interaction
diagnostic usage
unassigned
4
3
0
Acute Coronary Syndrome
Preanalytic considerations for using plasma myeloperoxidase as a biomarker in acute coronary syndrome.
diagnostic usage
ongoing research
therapeutic application
unassigned
3
1
1
0
Acute Coronary Syndrome
Identifying patients for early discharge: Performance of decision rules among patients with acute chest pain.
diagnostic usage
unassigned
3
0
Acute Coronary Syndrome
Usefulness of cardiac biomarker score for risk stratification in stable patients undergoing elective cardiac evaluation across glycemic status.
diagnostic usage
ongoing research
unassigned
4
2
0
Acute Coronary Syndrome
Myeloperoxidase and C-reactive protein in patients with cocaine-associated chest pain.
causal interaction
diagnostic usage
unassigned
4
3
0
Acute Coronary Syndrome
Diagnostic efficacy of myeloperoxidase to identify acute coronary syndrome in subjects with chest pain.
diagnostic usage
ongoing research
therapeutic application
unassigned
3
1
1
0
Acute Coronary Syndrome
Prediction of short-term clinical outcome of percutaneous coronary intervention in patients with acute coronary syndrome through myeloperoxidase levels.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
4
1
0
Acute Coronary Syndrome
A low-frequency variant in MAPK14 provides mechanistic evidence of a link with myeloperoxidase: a prognostic cardiovascular risk marker.
causal interaction
diagnostic usage
ongoing research
unassigned
4
3
1
0
Acute Coronary Syndrome
Sequential analysis of myeloperoxidase for prediction of adverse events after suspected acute coronary ischemia.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
4
3
0
Acute Coronary Syndrome
The relationship between fasting plasma glucose and MPO in patients with acute coronary syndrome.
causal interaction
diagnostic usage
ongoing research
unassigned
1
4
4
0
Acute Coronary Syndrome
Systemic and coronary levels of CRP, MPO, sCD40L and PlGF in patients with coronary artery disease.
diagnostic usage
ongoing research
unassigned
3
2
0
Acute Coronary Syndrome
A Synergistic Role of Myeloperoxidase and High Sensitivity Troponin T in the Early Diagnosis of Acute Coronary Syndrome.
causal interaction
diagnostic usage
ongoing research
unassigned
4
4
1
0
Acute Coronary Syndrome
Serum myeloperoxidase: a novel biomarker for evaluation of patients with acute coronary syndrome.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
4
4
2
Acute Coronary Syndrome
[Myeloperoxidase activity in blood plasma as a criterion of therapy for patients with cardiovascular disease].
causal interaction
unassigned
4
0
Acute Coronary Syndrome
Effect of collection tube type and freeze-thaw cycles on myeloperoxidase concentrations in blood samples of acute coronary syndrome patients.
causal interaction
diagnostic usage
ongoing research
therapeutic application
1
3
3
1
Acute Coronary Syndrome
Plasma Myeloperoxidase and Total Sialic Acid as Prognostic Indicators in Acute Coronary Syndrome.
diagnostic usage
ongoing research
unassigned
4
3
0
Acute Coronary Syndrome
Novel biomarkers for cardiovascular risk prediction.
causal interaction
diagnostic usage
ongoing research
unassigned
3
3
2
0
Acute Coronary Syndrome
Utility of myeloperoxidase in the differential diagnosis of acute coronary syndrome.
causal interaction
diagnostic usage
unassigned
4
4
0
Acute Coronary Syndrome
A single high-fat meal provokes pathological erythrocyte remodeling and increases myeloperoxidase levels: implications for acute coronary syndrome.
unassigned
0
Acute Coronary Syndrome
Amperometric myeloperoxidase immunoassay based on the use of CuPdPt nanowire networks.
therapeutic application
unassigned
1
0
Acute Coronary Syndrome
Myeloperoxidase level and inflammatory markers and lipid and lipoprotein parameters in stable coronary artery disease.
causal interaction
diagnostic usage
ongoing research
therapeutic application
2
4
4
1
Acute Coronary Syndrome
[Prognostic value of myeloperoxidase concentration in patients with acute coronary syndrome].
diagnostic usage
ongoing research
unassigned
4
3
0
Acute Coronary Syndrome
Role of myeloperoxidase in early diagnosis of acute myocardial infarction in patients admitted with chest pain.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
3
2
0
Acute Coronary Syndrome
Myeloperoxidase activity and acute coronary syndrome survival: long-term evaluation in the ERICO study.
ongoing research
therapeutic application
unassigned
4
1
0
Acute Coronary Syndrome
Platelet Serotonin Aggravates Myocardial Ischemia/Reperfusion Injury via Neutrophil Degranulation.
causal interaction
diagnostic usage
ongoing research
unassigned
2
4
1
0
Acute Coronary Syndrome
Temporal evolution of myeloperoxidase and galectin 3 during 1 year after acute coronary syndrome admission.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
3
2
1
Acute Coronary Syndrome
Prognostic Role of Elevated Myeloperoxidase in Patients with Acute Coronary Syndrome: A Systemic Review and Meta-Analysis.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
3
1
0
Acute Coronary Syndrome
Details on high frequency blood collection, data analysis, available material and patient characteristics in BIOMArCS.
diagnostic usage
ongoing research
unassigned
2
2
0
Acute Kidney Injury
Autoantibodies to native myeloperoxidase in patients with pulmonary hemorrhage and acute renal failure.
causal interaction
diagnostic usage
unassigned
4
4
0
Acute Kidney Injury
Antineutrophil cytoplasmic autoantibodies with myeloperoxidase specificity in a patient with anti-glomerular basement membrane disease.
causal interaction
ongoing research
unassigned
3
1
0
Acute Kidney Injury
Audit of the clinical usefulness of a rapid qualitative ELISA screen for antimyeloperoxidase and antiproteinase 3 antibodies in the assessment of patients with suspected vasculitis.
causal interaction
diagnostic usage
unassigned
2
3
0
Acute Kidney Injury
Preventive effect of Y-27632, a selective Rho-kinase inhibitor, on ischemia/reperfusion-induced acute renal failure in rats.
causal interaction
therapeutic application
unassigned
4
3
0
Acute Kidney Injury
Interleukin-6 mediates lung injury following ischemic acute kidney injury or bilateral nephrectomy.
ongoing research
therapeutic application
unassigned
4
3
0
Acute Kidney Injury
Microscopic polyangitis complicating double carcinoma of the stomach and duodenum: improvement after the resection of these carcinomas.
diagnostic usage
unassigned
4
0
Acute Kidney Injury
Pulmonary fibrosis-an uncommon manifestation of anti-myeloperoxidase-positive systemic vasculitis?
causal interaction
diagnostic usage
unassigned
1
1
0
Acute Kidney Injury
The mechanism of myocardium and pancreas injury in rabbits with acute renal failure might be related to myeloperoxidase and membrane pump activities.
diagnostic usage
unassigned
1
0
Acute Kidney Injury
Sesame oil prevents acute kidney injury induced by the synergistic action of aminoglycoside and iodinated contrast in rats.
causal interaction
ongoing research
unassigned
1
1
0
Acute Kidney Injury
Regional citrate anticoagulation reduces polymorphonuclear cell degranulation in critically ill patients treated with continuous venovenous hemofiltration.
ongoing research
therapeutic application
unassigned
1
2
0
Acute Kidney Injury
Churg-strauss syndrome presenting with acute renal insufficiency accompanied by eosinophilic tubulointerstitial nephritis.
unassigned
0
Acute Kidney Injury
Churg-Strauss syndrome presenting with acute kidney injury in a case of primary focal segmental glomerulosclerosis.
causal interaction
ongoing research
unassigned
2
1
0
Acute Kidney Injury
Chronic ethanol ingestion induces oxidative kidney injury through taurine-inhibitable inflammation.
causal interaction
unassigned
2
0
Acute Kidney Injury
Inhibition of glycogen synthase kinase-3? attenuates acute kidney injury in sodium taurocholate?induced severe acute pancreatitis in rats.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
4
4
2
Acute Kidney Injury
Inflammatory PAF Receptor Signaling Initiates Hedgehog Signaling and Kidney Fibrogenesis During Ethanol Consumption.
causal interaction
unassigned
1
0
Acute Lung Injury
Myeloperoxidase-induced inactivation of alpha 1-antiprotease in hamsters.
causal interaction
unassigned
2
0
Acute Lung Injury
Clinical significance of measuring myeloperoxidase, thiobarbituric acid reactive material and 7S collagen in plasma of patients with adult respiratory distress syndrome.
causal interaction
diagnostic usage
ongoing research
unassigned
4
3
3
0
Acute Lung Injury
[Measurement of myeloperoxidase and thiobarbituric acid-reactive material in plasma and bronchoalveolar lavage in E. coli-induced acute lung injury]
causal interaction
diagnostic usage
ongoing research
therapeutic application
1
3
2
1
Acute Lung Injury
Purification of myeloperoxidase from equine polymorphonuclear leucocytes.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
3
1
0
Acute Lung Injury
Effects of inhaled nitric oxide in a mouse model of sepsis-induced acute lung injury.
causal interaction
diagnostic usage
unassigned
4
2
0
Acute Lung Injury
Myeloperoxidase deficiency enhances inflammation after allogeneic marrow transplantation.
causal interaction
unassigned
4
0
Acute Lung Injury
Effective attenuation of acute lung injury in vivo and the formyl peptide-induced neutrophil activation in vitro by CYL-26z through the phosphoinositide 3-kinase gamma pathway.
ongoing research
therapeutic application
unassigned
2
1
0
Acute Lung Injury
The involvement of nitric oxide, nitric oxide synthase, neutrophil elastase, myeloperoxidase and proinflammatory cytokines in the acute lung injury caused by phorbol myristate acetate.
causal interaction
diagnostic usage
ongoing research
therapeutic application
1
2
1
1
Acute Lung Injury
IL-10 deficiency augments acute lung but not liver injury in hemorrhagic shock.
diagnostic usage
ongoing research
unassigned
4
2
0
Acute Lung Injury
15-epi-lipoxin A4 inhibits myeloperoxidase signaling and enhances resolution of acute lung injury.
causal interaction
unassigned
1
0
Acute Lung Injury
Critical role of IL-17RA in immunopathology of influenza infection.
causal interaction
unassigned
4
0
Acute Lung Injury
Early administration of propofol protects against endotoxin-induced acute lung injury in rats by inhibiting the TGF-beta1-Smad2 dependent pathway.
causal interaction
diagnostic usage
therapeutic application
unassigned
2
3
1
0
Acute Lung Injury
Therapeutic accessibility of caspase-mediated cell death as a key pathomechanism in indirect acute lung injury.
causal interaction
diagnostic usage
therapeutic application
unassigned
3
2
4
0
Acute Lung Injury
Heme oxygenase-1 upregulation improves lipopolysaccharide-induced acute lung injury involving suppression of macrophage migration inhibitory factor.
causal interaction
ongoing research
therapeutic application
unassigned
4
2
1
0
Acute Lung Injury
Heme Oxygenase-1 Mediates the Protective Effects of Ischemic Preconditioning on Mitigating Lung Injury Induced by Lower Limb Ischemia-Reperfusion in Rats.
causal interaction
ongoing research
unassigned
4
3
0
Acute Lung Injury
Long-term Simvastatin Administration Attenuates Lung Injury and Oxidative Stress in Murine Acute Lung Injury Models Induced by Oleic Acid and Endotoxin.
causal interaction
ongoing research
therapeutic application
unassigned
4
3
2
0
Acute Lung Injury
Intensive Insulin Treatment Attenuates Burn-Initiated Acute Lung Injury in Rats: Role of the Protective Endothelium.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
4
1
0
Acute Lung Injury
Cyptoporus polysaccharide prevents lipopolysaccharide-induced acute lung injury associated with down-regulating Toll-like receptor 2 expression.
causal interaction
ongoing research
therapeutic application
unassigned
3
4
1
0
Acute Lung Injury
Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: Role for the adenosine A(2A) receptor.
causal interaction
ongoing research
unassigned
1
2
0
Acute Lung Injury
p-Cymene protects mice against lipopolysaccharide-induced acute lung injury by inhibiting inflammatory cell activation.
therapeutic application
unassigned
2
0
Acute Lung Injury
Zingerone attenuates lipopolysaccharide-induced acute lung injury in mice.
causal interaction
diagnostic usage
unassigned
4
3
0
Acute Lung Injury
Histone deacetylase inhibitors trichostatin A and suberoylanilide hydroxamic acid attenuate ventilator-induced lung injury.
causal interaction
diagnostic usage
ongoing research
therapeutic application
3
4
4
1
Acute Lung Injury
Cyanidin-3-O-?-glucoside ameliorates lipopolysaccharide-induced acute lung injury by reducing TLR4 recruitment into lipid rafts.
causal interaction
therapeutic application
unassigned
3
3
0
Acute Lung Injury
Agmatine protects against zymosan-induced acute lung injury in mice by inhibiting NF-?B-mediated inflammatory response.
therapeutic application
unassigned
2
0
Acute Lung Injury
High-altitude pulmonary edema can be prevented by heat shock protein 70-mediated hyperbaric oxygen preconditioning.
causal interaction
diagnostic usage
ongoing research
therapeutic application
3
3
2
2
Acute Lung Injury
Formaldehyde inhalation during pregnancy abolishes the development of acute innate inflammation in offspring.
causal interaction
therapeutic application
unassigned
3
1
0
Acute Lung Injury
Smart imaging of acute lung injury: exploration of myeloperoxidase activity using in vivo endoscopic confocal fluorescence microscopy.
ongoing research
therapeutic application
unassigned
1
1
0
Acute Lung Injury
Absinthin attenuates LPS-induced ALI through MIP-1?-mediated inflammatory cell infiltration.
causal interaction
therapeutic application
unassigned
1
1
0
Acute Lung Injury
Hesperetin attenuates ventilator-induced acute lung injury through inhibition of NF-?B-mediated inflammation.
causal interaction
therapeutic application
unassigned
3
1
0
Acute Lung Injury
Pretreatment with the compound asperuloside decreases acute lung injury via inhibiting MAPK and NF-?B signaling in a murine model.
causal interaction
ongoing research
therapeutic application
unassigned
1
2
2
0
Acute Lung Injury
Hydrogen sulfide ameliorates acute lung injury induced by infrarenal aortic cross-clamping by inhibiting inflammation and angiopoietin 2 release.
causal interaction
diagnostic usage
ongoing research
therapeutic application
1
3
4
1
Acute Lung Injury
Synthesis and evaluation of 2-cyano-3, 12-dioxooleana-1, 9(11)-en-28-oate-13?, 28-olide as a potent anti-inflammatory agent for intervention of LPS-induced acute lung injury.
ongoing research
therapeutic application
unassigned
2
1
0
Acute Lung Injury
Oxygenation, inflammatory response and lung injury during one lung ventilation in rabbits using inspired oxygen fraction of 0.6 vs. 1.0.
unassigned
0
Acute Lung Injury
?-Nitrostyrene derivatives attenuate LPS-mediated acute lung injury via the inhibition of neutrophil-platelet interactions and NET release.
ongoing research
therapeutic application
unassigned
2
2
0
Acute Lung Injury
Andrographolide Sulfonate Attenuates Acute Lung Injury by Reducing Expression of Myeloperoxidase and Neutrophil-Derived Proteases in Mice.
causal interaction
ongoing research
therapeutic application
unassigned
2
2
1
0
Acute Lung Injury
Ganoderic acid A attenuates lipopolysaccharide-induced lung injury in mice.
therapeutic application
unassigned
1
0
Adenocarcinoma
Simultaneous progression of oxidative stress and angiogenesis in malignant transformation of Barrett esophagus.
ongoing research
unassigned
4
0
Adenocarcinoma
Myeloperoxidase and superoxide dismutase polymorphisms are associated with an increased risk of developing pancreatic adenocarcinoma.
causal interaction
diagnostic usage
unassigned
4
3
0
Adenocarcinoma
Evaluation of a 4-protein serum biomarker panel-biglycan, annexin-A6, myeloperoxidase, and protein S100-A9 (B-AMP)-for the detection of esophageal adenocarcinoma.
therapeutic application
unassigned
1
0
Adenocarcinoma
Early detection of high oxidative activity in patients with adenomatous intestinal polyps and colorectal adenocarcinoma: myeloperoxidase and oxidized low-density lipoprotein in serum as new markers of oxidative stress in colorectal cancer.
causal interaction
diagnostic usage
unassigned
4
4
0
Agammaglobulinemia
[A spectrophotometric method of determining the myeloperoxidase activity in phagocytic cells]
causal interaction
diagnostic usage
unassigned
4
4
0
Aggressive Periodontitis
Myeloperoxidase isoform activities released by human neutrophils in response to dental and periodontal bacteria.
causal interaction
diagnostic usage
unassigned
3
3
0
Aggressive Periodontitis
The importance of data presentation regarding gingival crevicular fluid myeloperoxidase and elastase-like activity in periodontal disease and health status.
diagnostic usage
ongoing research
unassigned
3
4
0
Aggressive Periodontitis
Amplified crevicular leukocyte activity in aggressive periodontal disease.
causal interaction
diagnostic usage
ongoing research
therapeutic application
1
2
1
1
Aggressive Periodontitis
Gingival crevicular fluid levels of calprotectin and myeloperoxidase during therapy for generalized aggressive periodontitis.
therapeutic application
unassigned
1
0
Aggressive Periodontitis
Genetic variation of myeloperoxidase gene contributes to aggressive periodontitis: a preliminary association study in Turkish population.
ongoing research
unassigned
2
0
Aggressive Periodontitis
Myeloperoxidase staining in the diagnosis of aggressive periodontitis.
diagnostic usage
therapeutic application
unassigned
4
1
0
Aggressive Periodontitis
Serum and salivary matrix metalloproteinases, neutrophil elastase, myeloperoxidase in patients with chronic or aggressive periodontitis.
causal interaction
ongoing research
unassigned
1
4
0
Aggressive Periodontitis
Evaluation of Local and Systemic Levels of Interleukin-17, Interleukin-23, and Myeloperoxidase in Response to Periodontal Therapy in Patients with Generalized Aggressive Periodontitis.
causal interaction
diagnostic usage
ongoing research
therapeutic application
1
4
3
3
Agranulocytosis
Serum myeloperoxidase and lactoferrin in neutropenia.
causal interaction
diagnostic usage
ongoing research
therapeutic application
1
4
2
1
Agranulocytosis
Comparative metabolism and covalent binding of procainamide by human leukocytes.
causal interaction
unassigned
4
0
Agranulocytosis
Interleukin-1-induced granulocytopenia and pulmonary leukostasis in rabbits.
causal interaction
diagnostic usage
unassigned
4
1
0
Agranulocytosis
Peroxidase-catalysed oxidation of different dibenzazepine derivatives.
diagnostic usage
unassigned
2
0
Agranulocytosis
Carbamazepine metabolism to a reactive intermediate by the myeloperoxidase system of activated neutrophils.
causal interaction
therapeutic application
unassigned
2
1
0
Agranulocytosis
Activation of CGS 12094 (prinomide metabolite) to 1,4-benzoquinone by myeloperoxidase: implications for human idiosyncratic agranulocytosis.
ongoing research
unassigned
1
0
Agranulocytosis
Clozapine-induced agranulocytosis and hereditary polymorphisms of clozapine metabolizing enzymes: no association with myeloperoxidase and cytochrome P4502D6.
unassigned
0
Agranulocytosis
Impact of myeloperoxidase and NADPH-oxidase polymorphisms in drug-induced agranulocytosis.
diagnostic usage
therapeutic application
unassigned
2
1
0
Agranulocytosis
Aminoglutethimide-induced protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis.
causal interaction
diagnostic usage
therapeutic application
unassigned
2
1
4
0
Agranulocytosis
Procainamide, but not N-acetylprocainamide, induces protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis.
therapeutic application
unassigned
1
0
Agranulocytosis
Drug-induced protein free radical formation is attenuated by unsaturated Fatty acids by scavenging drug-derived phenyl radical metabolites.
causal interaction
therapeutic application
unassigned
3
2
0
Agranulocytosis
Involvement of Myeloperoxidase and NADPH Oxidase in the Covalent Binding of Amodiaquine and Clozapine to Neutrophils: Implications for Drug-Induced Agranulocytosis.
diagnostic usage
therapeutic application
unassigned
2
2
0
Agranulocytosis
Cocaine-Induced Vasculitis.
causal interaction
unassigned
3
0
Airway Obstruction
Airway inflammation in smokers with nonobstructive and obstructive chronic bronchitis.
causal interaction
unassigned
3
0
Airway Obstruction
Myeloperoxidase concentration in bronchoalveolar lavage fluid from healthy horses and those with recurrent airway obstruction.
diagnostic usage
ongoing research
unassigned
2
3
0
Airway Obstruction
Combined recombinant human activated protein C and ceftazidime prevent the onset of acute respiratory distress syndrome in severe sepsis.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
2
4
3
Alveolar Bone Loss
Protective effect of locally applied carvacrol gel on ligature-induced periodontitis in rats: a tapping mode AFM study.
causal interaction
unassigned
2
0
Alveolar Bone Loss
Short-term induction of thrombocytopenia delays periodontal healing in rats with periodontal disease: participation of endostatin and vascular endothelial growth factor.
causal interaction
ongoing research
therapeutic application
unassigned
2
2
1
0
Alveolar Bone Loss
Nafamostat mesilate, a potent tryptase inhibitor, modulates periodontitis in rats.
diagnostic usage
ongoing research
therapeutic application
unassigned
4
4
3
0
Alveolar Bone Loss
Effects of calcium gluconate on experimental periodontitis and alveolar bone loss in rats.
diagnostic usage
ongoing research
unassigned
1
3
0
Alveolar Bone Loss
Effects of Polycan, a ?-glucan, on experimental periodontitis and alveolar bone loss in Sprague-Dawley rats.
diagnostic usage
ongoing research
unassigned
3
3
0
Alveolar Bone Loss
Effects of Melatonin on Oxidative Stress Index and Alveolar Bone Loss in Diabetic Rats With Periodontitis.
diagnostic usage
ongoing research
unassigned
3
3
0
Alveolar Bone Loss
The Effects of Topical Application of Polycal (a 2:98 (g/g) Mixture of Polycan and Calcium Gluconate) on Experimental Periodontitis and Alveolar Bone Loss in Rats.
diagnostic usage
ongoing research
unassigned
2
4
0
Alveolar Bone Loss
Decrease of Pericytes is Associated With Liver Disease Caused by Ligature-Induced Periodontitis in Rats.
ongoing research
unassigned
3
0
Alveolar Bone Loss
Periodontitis changes renal structures by oxidative stress and lipid peroxidation.
diagnostic usage
unassigned
3
0
Alveolar Bone Loss
Steatosis caused by experimental periodontitis is reversible after removal of ligature in rats.
causal interaction
diagnostic usage
ongoing research
unassigned
1
1
2
0
Alveolar Bone Loss
Orabase formulation with cashew gum polysaccharide decreases inflammatory and bone loss hallmarks in experimental periodontitis.
causal interaction
unassigned
3
0
Alveolar Bone Loss
One or two ligatures inducing periodontitis are sufficient to cause fatty liver.
ongoing research
unassigned
2
0
Alveolar Bone Loss
Sulfated polysaccharides from the marine algae Gracilaria caudata prevent tissue damage caused by ligature-induced periodontitis.
ongoing research
unassigned
1
0
Alzheimer Disease
Apolipoprotein E is highly susceptible to oxidation by myeloperoxidase, an enzyme present in the brain.
causal interaction
unassigned
2
0
Alzheimer Disease
Myeloperoxidase polymorphism is associated with gender specific risk for Alzheimer's disease.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
3
2
0
Alzheimer Disease
Association between Alzheimer's disease and a functional polymorphism in the Myeloperoxidase gene.
causal interaction
ongoing research
unassigned
3
4
0
Alzheimer Disease
The myeloperoxidase gene in Alzheimer's disease: a case-control study and meta-analysis.
causal interaction
ongoing research
unassigned
4
4
0
Alzheimer Disease
Myeloperoxidase G-463A polymorphism and Alzheimer's disease in the ApoEurope study.
ongoing research
unassigned
2
0
Alzheimer Disease
Peroxisome proliferator-activated receptor gamma ligands regulate myeloperoxidase expression in macrophages by an estrogen-dependent mechanism involving the -463GA promoter polymorphism.
causal interaction
therapeutic application
unassigned
4
1
0
Alzheimer Disease
Neuronal expression of myeloperoxidase is increased in Alzheimer's disease.
causal interaction
unassigned
4
0
Alzheimer Disease
No Genetic Association between the Myeloperoxidase Gene -463 Polymorphism and Estrogen Receptor-alpha Gene Polymorphisms and Japanese Sporadic Alzheimer's Disease.
causal interaction
ongoing research
unassigned
4
2
0
Alzheimer Disease
Myeloperoxidase polymorphism and cognitive decline in older adults in the Health, Aging, and Body Composition Study.
causal interaction
unassigned
4
0
Alzheimer Disease
Oxidized plasma high-density lipoprotein is decreased in Alzheimer's disease.
causal interaction
unassigned
4
0
Alzheimer Disease
Aberrant expression of myeloperoxidase in astrocytes promotes phospholipid oxidation and memory deficits in a mouse model of Alzheimer disease.
ongoing research
unassigned
2
0
Alzheimer Disease
Increased myeloperoxidase plasma levels in patients with Alzheimer's disease.
causal interaction
diagnostic usage
unassigned
4
4
0
Alzheimer Disease
Observation of the multiple halogenation of peptides in the electrospray ionization source.
causal interaction
unassigned
1
0
Alzheimer Disease
Myeloperoxidase: Bridging the gap in neurodegeneration.
causal interaction
therapeutic application
unassigned
4
4
0
Alzheimer Disease
Myeloperoxidase Deficiency Inhibits Cognitive Decline in the 5XFAD Mouse Model of Alzheimer's Disease.
causal interaction
unassigned
2
0
Amyloidosis
[Changes in leukocyte enzyme activity during experimental amyloidogenesis and in patients with amyloidosis]
diagnostic usage
ongoing research
unassigned
3
2
0
Amyotrophic Lateral Sclerosis
Myeloperoxidase: Bridging the gap in neurodegeneration.
causal interaction
therapeutic application
unassigned
4
4
0
Anemia
Myeloperoxidase activity of polymorphonuclear leukocytes in iron deficiency anemia and anemia of chronic disorders.
causal interaction
ongoing research
unassigned
1
2
0
Anemia
Myeloperoxidase activity in polymorphonuclear neutrophils in nutritional anaemia.
diagnostic usage
unassigned
1
0
Anemia
Increased in vivo activation of neutrophils and complement in sickle cell disease.
diagnostic usage
ongoing research
unassigned
4
3
0
Anemia
Inhibition of dextran sulphate sodium (DSS)-induced colitis in mice by intracolonically administered antibodies against adhesion molecules (endothelial leucocyte adhesion molecule-1 (ELAM-1) or intercellular adhesion molecule-1 (ICAM-1)).
causal interaction
unassigned
1
0
Anemia
[Antineutrophil cytoplasmic antibodies in patients with sickle cell anemia]
diagnostic usage
ongoing research
unassigned
1
2
0
Anemia
Association of the G-463A myeloperoxidase polymorphism with infection in sickle cell anemia.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
1
1
0
Anemia
Churg-strauss syndrome presenting with diffuse alveolar hemorrhage and rapidly progressive glomerulonephritis.
causal interaction
unassigned
1
0
Anemia
Association between systemic neutrophil gelatinase-associated lipocalin and anemia, relative hypochromia, and inflammation in chronic systolic heart failure.
diagnostic usage
ongoing research
unassigned
4
2
0
Anemia
Supplementation of the diet with Salecan attenuates the symptoms of colitis induced by dextran sulphate sodium in mice.
causal interaction
therapeutic application
unassigned
2
1
0
Anemia
Partial replacement of dietary linoleic acid with long chain n-3 polyunsaturated fatty acids protects against dextran sulfate sodium-induced colitis in rats.
causal interaction
diagnostic usage
unassigned
2
2
0
Anemia
Increased oxidative stress alters nucleosides metabolite levels in sickle cell anemia.
diagnostic usage
ongoing research
unassigned
4
2
0
Anemia
High serum hepcidin is associated with the occurrence of anemia in anti-myeloperoxidase antibody-associated vasculitis with normal kidney function: a cross-sectional study.
diagnostic usage
ongoing research
unassigned
3
4
0
Anemia, Aplastic
Acquired myeloperoxidase deficiency of neutrophils in a patient with aplastic anemia (idiopathic marrow aplasia).
causal interaction
diagnostic usage
unassigned
4
1
0
Anemia, Aplastic
Role of myeloperoxidase index in differentiation of megaloblastic and aplastic anemia.
causal interaction
diagnostic usage
ongoing research
unassigned
1
2
2
0
Anemia, Hemolytic, Autoimmune
Crescentic glomerulonephritis with positive antineutrophil cytoplasmic autoantibody specific for myeloperoxidase associated with autoimmune hemolytic anemia and thrombocytopenic purpura.
causal interaction
diagnostic usage
unassigned
2
3
0
Anemia, Iron-Deficiency
Myeloperoxidase activity of polymorphonuclear leukocytes in iron deficiency anemia and anemia of chronic disorders.
causal interaction
ongoing research
unassigned
1
2
0
Anemia, Megaloblastic
Neutrophil myeloperoxidase measurement uncovers masked megaloblastic anemia.
causal interaction
ongoing research
therapeutic application
unassigned
1
2
1
0
Anemia, Refractory
Quantitative iodination of human blood polymorphonuclear leukocytes.
diagnostic usage
therapeutic application
unassigned
3
3
0
Anemia, Refractory
Myeloperoxidase-deficient polymorphonuclear leucocytes. (V): Relation to FAB-classification and neutrophil alkaline phosphatase activity in primary myelodysplastic syndromes.
diagnostic usage
ongoing research
therapeutic application
unassigned
3
2
1
0
Anemia, Sickle Cell
Quantitative iodination of human blood polymorphonuclear leukocytes.
diagnostic usage
therapeutic application
unassigned
3
3
0
Anemia, Sickle Cell
Increased in vivo activation of neutrophils and complement in sickle cell disease.
diagnostic usage
ongoing research
unassigned
4
3
0
Anemia, Sickle Cell
[Antineutrophil cytoplasmic antibodies in patients with sickle cell anemia]
diagnostic usage
ongoing research
unassigned
1
2
0
Anemia, Sickle Cell
Association of the G-463A myeloperoxidase polymorphism with infection in sickle cell anemia.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
1
1
0
Anemia, Sickle Cell
Inhibition of Myeloperoxidase Decreases Vascular Oxidative Stress and Increases Vasodilatation in Sickle Cell Disease Mice.
causal interaction
ongoing research
therapeutic application
unassigned
4
4
1
0
Anemia, Sickle Cell
Increased oxidative stress alters nucleosides metabolite levels in sickle cell anemia.
diagnostic usage
ongoing research
unassigned
4
2
0
Aneurysm
The inflammatory response to stent grafting of the thoracic aorta.
causal interaction
diagnostic usage
unassigned
4
1
0
Aneurysm
Ruptured giant aneurysm of the left anterior descending coronary artery in Kawasaki disease.
causal interaction
therapeutic application
unassigned
2
1
0
Aneurysm
Carotid artery brain aneurysm model: in vivo molecular enzyme-specific MR imaging of active inflammation in a pilot study.
ongoing research
therapeutic application
unassigned
3
1
0
Aneurysm
Myeloperoxidase in Human Intracranial Aneurysms: Preliminary Evidence.
causal interaction
ongoing research
unassigned
2
4
0
Aneurysm
MR imaging of myeloperoxidase activity in a model of the inflamed aneurysm wall.
diagnostic usage
ongoing research
therapeutic application
unassigned
2
2
3
0
Aneurysm
Myeloperoxidase is increased in human cerebral aneurysms and increases formation and rupture of cerebral aneurysms in mice.
causal interaction
diagnostic usage
ongoing research
unassigned
4
3
2
0
Aneurysm
The role of oxidative stress as a risk factor for rupture of posterior inferior cerebellar artery aneurysms.
diagnostic usage
ongoing research
unassigned
4
4
0
Aneurysm, Ruptured
The role of oxidative stress as a risk factor for rupture of posterior inferior cerebellar artery aneurysms.
diagnostic usage
ongoing research
unassigned
4
4
0
Angina Pectoris
KORVITIN REDUCES THE HIGH MAINTENANCE OF MYELOPEROXIDASE IN PLASMA OF BLOOD OF PATIENTS WITH THE ACUTE INFARCT OF MYOCARDIUM.
diagnostic usage
ongoing research
unassigned
2
1
0
Angina, Stable
Intracellular neutrophil myeloperoxidase is reduced in unstable angina and acute myocardial infarction, but its reduction is not related to ischemia.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
4
3
3
Angina, Stable
Widespread coronary inflammation in unstable angina.
causal interaction
ongoing research
therapeutic application
unassigned
4
3
3
0
Angina, Stable
Acute neutrophil activation in direct stenting: comparison of stable and unstable angina patients.
causal interaction
diagnostic usage
ongoing research
unassigned
2
4
2
0
Angina, Stable
Coronary stenting is associated with an acute increase in plasma myeloperoxidase in stable angina patients but not in patients with acute myocardial infarction.
causal interaction
diagnostic usage
ongoing research
unassigned
4
4
2
0
Angina, Stable
Prognostic value of myeloperoxidase in coronary artery disease: comparison of unstable and stable angina patients.
causal interaction
diagnostic usage
ongoing research
unassigned
4
4
1
0
Angina, Stable
Myeloperoxidase levels predicts angiographic severity of coronary artery disease in patients with chronic stable angina.
causal interaction
diagnostic usage
ongoing research
unassigned
1
3
1
0
Angina, Stable
Systemic and coronary levels of CRP, MPO, sCD40L and PlGF in patients with coronary artery disease.
diagnostic usage
ongoing research
unassigned
3
2
0
Angina, Stable
[Myeloperoxidase activity in blood plasma as a criterion of therapy for patients with cardiovascular disease].
causal interaction
unassigned
4
0
Angina, Stable
Altered human neutrophil Fc?RI and Fc?RIII but not Fc?RII expression is associated with the acute coronary event in patients with coronary artery disease.
ongoing research
unassigned
2
0
Angina, Stable
Local Matrix Metalloproteinase 9 Level Determines Early Clinical Presentation of ST-Segment-Elevation Myocardial Infarction.
causal interaction
diagnostic usage
therapeutic application
unassigned
3
3
4
0
Angina, Unstable
Intracellular neutrophil myeloperoxidase is reduced in unstable angina and acute myocardial infarction, but its reduction is not related to ischemia.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
4
3
3
Angina, Unstable
[Activation of the antibacterial properties and neutrophil myeloperoxidase and acid phosphatase in patients with unstable angina pectoris]
causal interaction
diagnostic usage
ongoing research
therapeutic application
1
4
4
1
Angina, Unstable
Widespread coronary inflammation in unstable angina.
causal interaction
ongoing research
therapeutic application
unassigned
4
3
3
0
Angina, Unstable
Acute neutrophil activation in direct stenting: comparison of stable and unstable angina patients.
causal interaction
diagnostic usage
ongoing research
unassigned
2
4
2
0
Angina, Unstable
Increased expression and plasma levels of myeloperoxidase are closely related to the presence of angiographically-detected complex lesion morphology in unstable angina.
diagnostic usage
unassigned
3
0
Angina, Unstable
Circulating adhesion molecules, matrix metalloproteinase-9, plasminogen activator inhibitor-1, and myeloperoxidase in coronary artery disease patients with stable and unstable angina.
causal interaction
diagnostic usage
ongoing research
therapeutic application
2
3
4
2
Angina, Unstable
Curcumin effects on myeloperoxidase, interleukin-18 and matrix metalloproteinase-9 inflammatory biomarkers in patients with unstable angina: A randomized clinical trial.
diagnostic usage
ongoing research
therapeutic application
unassigned
1
4
2
0
Anti-Glomerular Basement Membrane Disease
Prognostic implication of anti-neutrophil cytoplasmic autoantibodies with myeloperoxidase specificity in anti-glomerular basement membrane disease.
diagnostic usage
unassigned
1
0
Anti-Glomerular Basement Membrane Disease
[A case of Goodpasture's syndrome. Myeloperoxidase antibodies as a valuable serological marker in vasculitis]
diagnostic usage
therapeutic application
unassigned
4
1
0
Anti-Glomerular Basement Membrane Disease
Antineutrophil cytoplasmic autoantibodies with myeloperoxidase specificity in a patient with anti-glomerular basement membrane disease.
causal interaction
ongoing research
unassigned
3
1
0
Anti-Glomerular Basement Membrane Disease
[A case of Goodpasture's syndrome with myeloperoxidase specific anti-neutrophil cytoplasmic autoantibody (MPO-ANCA) during chronic interstitial pneumonia]
causal interaction
ongoing research
unassigned
4
1
0
Anti-Glomerular Basement Membrane Disease
Anti-glomerular basement membrane (anti-GBM) disease accompanied by vasculitis that was not positive for antineutrophil cytoplasmic antibodies to myeloperoxidase and proteinase 3: a report of two cases and the incidence of anti-GBM disease at one institution.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
2
1
0
Anti-Glomerular Basement Membrane Disease
Anti-GBM disease and ANCA during dengue infection.
diagnostic usage
unassigned
2
0
Anti-Glomerular Basement Membrane Disease
Autoantibodies against Linear Epitopes of Myeloperoxidase in Anti-Glomerular Basement Membrane Disease.
diagnostic usage
ongoing research
therapeutic application
unassigned
3
2
1
0
Anti-Glomerular Basement Membrane Disease
Pre-existing chronic interstitial pneumonia is a poor prognostic factor of Goodpasture's syndrome: a case report and review of the literature.
causal interaction
diagnostic usage
ongoing research
unassigned
1
1
3
0
Anti-Glomerular Basement Membrane Disease
AP-VAS 2012 case report: anti-glomerular basement membrane disease with high titer of myeloperoxidase anti-neutrophil cytoplasmic antibody-an autopsy case report.
causal interaction
unassigned
3
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Does the presence of ANCA in patients with ulcerative colitis necessarily imply renal involvement?
diagnostic usage
therapeutic application
unassigned
4
1
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Endothelial tissue factor stimulation by proteinase 3 and elastase.
causal interaction
therapeutic application
unassigned
1
1
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Serial ANCA titers: useful tool for prevention of relapses in ANCA-associated vasculitis.
ongoing research
unassigned
3
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
The role of myeloperoxidase in the pathogenesis of systemic vasculitis.
causal interaction
unassigned
2
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
No association of G-463A myeloperoxidase gene polymorphism with MPO-ANCA-associated vasculitis.
causal interaction
ongoing research
unassigned
4
3
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Newer insights into the aetiology and pathogenesis of myeloperoxidase associated autoimmunity.
causal interaction
unassigned
4
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Off balance: T-cells in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides.
ongoing research
unassigned
1
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
[Microscopic polyangiitis]
unassigned
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Meta-analysis of myeloperoxidase G-463/A polymorphism in anti-neutrophil cytoplasmic autoantibody-positive vasculitis.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
3
1
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Complement activation is involved in renal damage in human antineutrophil cytoplasmic autoantibody associated pauci-immune vasculitis.
causal interaction
diagnostic usage
ongoing research
therapeutic application
1
4
4
1
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Th17 Cells Promote Autoimmune Anti-Myeloperoxidase Glomerulonephritis.
causal interaction
therapeutic application
unassigned
4
3
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Mast cells contribute to peripheral tolerance and attenuate autoimmune vasculitis.
ongoing research
therapeutic application
unassigned
3
1
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Thymic Deletion and Regulatory T Cells Prevent Antimyeloperoxidase GN.
causal interaction
unassigned
2
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Epitope analysis of anti-myeloperoxidase antibodies in patients with ANCA-associated vasculitis.
causal interaction
diagnostic usage
unassigned
2
1
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Remarks on the Asia Pacific Meeting of Vasculitis and ANCA Workshop 2012.
unassigned
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Clinical trial for Japanese patients with myeloperoxidase anti-neutrophil cytoplasmic antibody-associated vasculitis: the JMAAV study.
diagnostic usage
ongoing research
therapeutic application
unassigned
4
2
3
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Epitope analysis of anti-myeloperoxidase antibodies in propylthiouracil-induced antineutrophil cytoplasmic antibody-associated vasculitis.
causal interaction
unassigned
1
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Simultaneous automated screening and confirmatory testing for vasculitis-specific ANCA.
diagnostic usage
therapeutic application
unassigned
1
1
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
ANCA as a Predictor of Relapse: Useful in Patients with Renal Involvement But Not in Patients with Nonrenal Disease.
diagnostic usage
ongoing research
therapeutic application
unassigned
2
2
1
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Direct and indirect pathogenic roles of autoantibodies in systemic autoimmune diseases.
unassigned
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Comparison of a novel chemiluminescence enzyme immunoassay (CLEIA) with enzyme-linked immunosorbent assay (ELISA) for the determination of MPO-ANCA in patients with ANCA-associated vasculitis.
ongoing research
unassigned
1
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Pathogenesis of anti-neutrophil cytoplasmic antibody-associated vasculitis: challenges and solutions 2014.
unassigned
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Emerging concepts in the pathogenesis of antineutrophil cytoplasmic antibody-associated vasculitis.
causal interaction
therapeutic application
unassigned
2
1
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Clinical analysis of patients with myeloperoxidase antineutrophil cytoplasmic antibody-associated vasculitis.
diagnostic usage
ongoing research
unassigned
4
3
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Diagnostic ANCA algorithms in daily clinical practice: evidence, experience, and effectiveness.
diagnostic usage
unassigned
2
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
CD8+ T Cells Effect Glomerular Injury in Experimental Anti-Myeloperoxidase GN.
causal interaction
unassigned
3
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Deglycosylation influences the oxidation activity and antigenicity of myeloperoxidase.
causal interaction
unassigned
2
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Gene-Specific DNA Methylation Changes Predict Remission in Patients with ANCA-Associated Vasculitis.
ongoing research
unassigned
3
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Comparison of enzyme-linked immunosorbent assay and rapid chemiluminescent analyser in the detection of myeloperoxidase and proteinase 3 autoantibodies.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
4
1
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Association Between Reappearance of Myeloperoxidase-Antineutrophil Cytoplasmic Antibody and Relapse in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: Subgroup Analysis of Nationwide Prospective Cohort Studies.
diagnostic usage
ongoing research
unassigned
2
4
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Alkylating histone deacetylase inhibitors may have therapeutic value in experimental myeloperoxidase-ANCA vasculitis.
causal interaction
therapeutic application
unassigned
4
4
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Relationship between serologic profile (ANCA type) and clinical features of renal involvement in ANCA-associated vasculitides.
diagnostic usage
ongoing research
therapeutic application
unassigned
3
2
1
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Immunoglobulins G from patients with ANCA-associated vasculitis are atypically glycosylated in both the Fc and Fab regions and the relation to disease activity.
unassigned
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Microparticles expressing myeloperoxidase and complement C3a and C5a as markers of renal involvement in antineutrophil cytoplasmic antibody - associated vasculitis.
diagnostic usage
ongoing research
unassigned
2
3
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
The association of airway comorbidities with the clinical phenotypes and outcomes of ANCA-associated vasculitis patients.
diagnostic usage
ongoing research
unassigned
2
3
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
The Diagnostic and Clinical Utility of Autoantibodies in Systemic Vasculitis.
causal interaction
diagnostic usage
unassigned
1
2
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Exploring Frequencies of Circulating Specific Th17 Cells against Myeloperoxidase and Proteinase 3 in ANCA Associated Vasculitis.
ongoing research
therapeutic application
unassigned
2
3
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Proteinase 3 (PR3)-antineutrophil cytoplasmic antibody (ANCA)-associated vasculitic neuropathy in diffuse cutaneous systemic sclerosis: a rare duo.
causal interaction
diagnostic usage
ongoing research
unassigned
4
1
1
0
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Therapeutic Myeloperoxidase Inhibition Attenuates Neutrophil Activation, ANCA-Mediated Endothelial Damage, and Crescentic GN.
causal interaction
diagnostic usage
ongoing research
therapeutic application
2
1
4
1
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Anti-neutrophil Cytoplasmic Antibodies (ANCA) as Disease Activity Biomarkers in a "Personalized Medicine Approach" in ANCA-Associated Vasculitis.
therapeutic application
unassigned
1
0
Antiphospholipid Syndrome
Antineutrophil cytoplasmic antibody (ANCA)-positive cutaneous leukocytoclastic vasculitis induced by propylthiouracil confirmed by positive patch test: a case report and review of the literature.
therapeutic application
unassigned
3
0
Anuria
An unusual presentation of antineutrophil cytoplasmic antibody-associated vasculitis: discrepancy between histopathology and clinical presentation.
ongoing research
therapeutic application
unassigned
1
1
0
Aortic Aneurysm, Abdominal
Elevated MMP-8 and decreased myeloperoxidase concentrations associate significantly with the risk for peripheral atherosclerosis disease and abdominal aortic aneurysm.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
4
1
0
Aortic Aneurysm, Abdominal
Role of myeloperoxidase in abdominal aortic aneurysm formation: mitigation by taurine.
causal interaction
ongoing research
therapeutic application
unassigned
1
1
1
0
Aortic Aneurysm, Abdominal
Identification of novel diagnostic and prognostic biomarkers for abdominal aortic aneurysm.
causal interaction
diagnostic usage
unassigned
4
4
0
Aortic Valve Stenosis
Myeloperoxidase and progression of aortic valve stenosis in patients undergoing hemodialysis.
causal interaction
diagnostic usage
therapeutic application
unassigned
2
1
1
0
Aortic Valve Stenosis
Aortic valve replacement in a patient with MPO-ANCA-positive Goodpasture disease.
causal interaction
unassigned
1
0
Aortitis
Successful treatment of refractory aortitis in antineutrophil cytoplasmic antibody-associated vasculitis using tocilizumab.
diagnostic usage
therapeutic application
unassigned
2
1
0
Apnea
Hypoxia/reoxygenation and vitamin C intake influence NO synthesis and antioxidant defenses of neutrophils.
causal interaction
therapeutic application
unassigned
2
1
0
Appendicitis
Can new inflammatory markers improve the diagnosis of acute appendicitis?
diagnostic usage
ongoing research
therapeutic application
unassigned
3
1
1
0
Appendicitis
The Use of Delta Neutrophil Index and Myeloperoxidase Index for Predicting Acute Complicated Appendicitis in Children.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
4
2
0
Appendicitis
Composition of the cellular infiltrate in patients with simple and complex appendicitis.
diagnostic usage
ongoing research
unassigned
2
1
0
Arteriosclerosis
[Myeloperoxidase of neutrophils and its possible role in lipid peroxidation processes in arteriosclerosis]
diagnostic usage
ongoing research
therapeutic application
unassigned
2
3
1
0
Arteriosclerosis
[Myeloperoxidase activity in patients with complicated arteriosclerosis and in their relatives]
causal interaction
diagnostic usage
ongoing research
unassigned
4
3
2
0
Arteriovenous Fistula
Predictive value of serum myeloperoxidase activity for thrombosis of arteriovenous fistulas.
diagnostic usage
therapeutic application
unassigned
4
1
0
Arteriovenous Malformations
Evidence of inflammatory cell involvement in brain arteriovenous malformations.
causal interaction
diagnostic usage
unassigned
3
2
0
Arteritis
-463 G/A myeloperoxidase promoter polymorphism in giant cell arteritis.
diagnostic usage
ongoing research
therapeutic application
unassigned
4
3
1
0
Arteritis
Detailed protocol to assess in vivo and ex vivo myeloperoxidase activity in mouse models of vascular inflammation and disease using hydroethidine.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
2
1
0
Arteritis
A case of PR3-ANCA-positive anti-GBM disease associated with intrarenal arteritis and thrombotic microangiopathy.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
1
2
0
Arthralgia
Cocaine-Induced Vasculitis.
causal interaction
unassigned
3
0
Arthritis
Perpetuation of inflammation associated with experimental arthritis: the role of macrophage activation by neutrophilic myeloperoxidase.
causal interaction
ongoing research
unassigned
1
2
0
Arthritis
Neutrophilic myeloperoxidase-macrophage interactions perpetuate chronic inflammation associated with experimental arthritis.
causal interaction
ongoing research
unassigned
2
2
0
Arthritis
Anti-lactoferrin antibodies and other types of anti-neutrophil cytoplasmic antibodies (ANCA) in reactive arthritis and ankylosing spondylitis.
diagnostic usage
ongoing research
unassigned
4
4
0
Arthritis
Kupffer-cell depletion attenuates colonic and extracolonic granulomatous inflammation in chronic colitis.
unassigned
0
Arthritis
Nitric oxide-derived species in synovial fluid from patients with juvenile idiopathic arthritis.
diagnostic usage
ongoing research
unassigned
1
1
0
Arthritis
Immunomodulatory and anti-inflammatory effects of Semecarpus anacardium LINN. Nut milk extract in experimental inflammatory conditions.
ongoing research
unassigned
3
0
Arthritis
Is Taurolidine a candidate for treatment of rheumatoid arthritis?
causal interaction
diagnostic usage
ongoing research
unassigned
2
4
2
0
Arthritis
Restorative and synergistic efficacy of Kalpaamruthaa, a modified Siddha preparation, on an altered antioxidant status in adjuvant induced arthritic rat model.
ongoing research
therapeutic application
unassigned
2
1
0
Arthritis
Effects of infliximab on cytokines, myeloperoxidase, and soluble adhesion molecules in patients with juvenile idiopathic arthritis.
ongoing research
therapeutic application
unassigned
4
1
0
Arthritis
Melatonin is a potent inhibitor for myeloperoxidase.
causal interaction
therapeutic application
unassigned
4
1
0
Arthritis
Antineutrophil Cytoplasmic Antibodies, Autoimmune Neutropenia, and Vasculitis.
diagnostic usage
therapeutic application
unassigned
1
2
0
Arthritis
Combination of carvacrol with methotrexate suppresses Complete Freund's Adjuvant induced synovial inflammation with reduced hepatotoxicity in rats.
causal interaction
therapeutic application
unassigned
1
1
0
Arthritis
Endogenous myeloperoxidase is a mediator of joint inflammation and damage in experimental arthritis.
causal interaction
unassigned
2
0
Arthritis
Differential regulatory role of pituitary adenylate cyclase-activating polypeptide in the serum-transfer arthritis model.
causal interaction
therapeutic application
unassigned
3
1
0
Arthritis
Nimesulide improves the symptomatic and disease modifying effects of leflunomide in collagen induced arthritis.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
2
4
0
Arthritis
Evaluation of Anti-inflammatory Activity of Seeds of Phalaris canariensis.
causal interaction
diagnostic usage
ongoing research
therapeutic application
2
1
1
1
Arthritis
Increased carotid artery intima-media thickness and myeloperoxidase level in children with newly diagnosed juvenile idiopathic arthritis.
causal interaction
diagnostic usage
unassigned
1
1
0
Arthritis
Antinociceptive and antidepressant-like effects of the crude extract of Vitex megapotamica in rats.
ongoing research
unassigned
1
0
Arthritis
The Impacts of Chrysanthemum indicum Extract on Oxidative Stress and Inflammatory Responses in Adjuvant-Induced Arthritic Rats.
diagnostic usage
ongoing research
therapeutic application
unassigned
4
1
1
0
Arthritis
Scientific validation of Anti-arthritic effect of Kashayams - a polyherbal formulation in collagen induced arthritic rats.
causal interaction
diagnostic usage
unassigned
4
1
0
Arthritis
Subantimicrobial Dose Doxycycline Worsens Chronic Arthritis-Induced Bone Microarchitectural Alterations in a Mouse Model: Role of Matrix Metalloproteinases?
causal interaction
therapeutic application
unassigned
4
1
0
Arthritis
Effect of quercetin on E-NTPDase/E-ADA activities and cytokine secretion of complete Freund adjuvant-induced arthritic rats.
causal interaction
diagnostic usage
therapeutic application
unassigned
2
2
1
0
Arthritis
TRPA1 Ion Channel Determines Beneficial and Detrimental Effects of GYY4137 in Murine Serum-Transfer Arthritis.
causal interaction
ongoing research
therapeutic application
unassigned
1
3
1
0
Arthritis, Experimental
Suppression of carrageenan- and collagen II-induced inflammation in mice by geranium oil.
diagnostic usage
therapeutic application
unassigned
1
1
0
Arthritis, Experimental
Bis(phenylimidazoselenazolyl) diselenide elicits antinociceptive effect by modulating myeloperoxidase activity, NOx and NFkB levels in the collagen-induced arthritis mouse model.
ongoing research
unassigned
1
0
Arthritis, Experimental
Clitoria ternatea flower petals: Effect on TNFR1 neutralization via downregulation of synovial matrix metalloproteases.
causal interaction
ongoing research
therapeutic application
unassigned
2
2
4
0
Arthritis, Experimental
Standardized Xylocarpus moluccensis fruit fraction mitigates collagen-induced arthritis in mice by regulating immune response.
diagnostic usage
unassigned
1
0
Arthritis, Juvenile
Nitric oxide-derived species in synovial fluid from patients with juvenile idiopathic arthritis.
diagnostic usage
ongoing research
unassigned
1
1
0
Arthritis, Juvenile
Effects of infliximab on cytokines, myeloperoxidase, and soluble adhesion molecules in patients with juvenile idiopathic arthritis.
ongoing research
therapeutic application
unassigned
4
1
0
Arthritis, Juvenile
Increased carotid artery intima-media thickness and myeloperoxidase level in children with newly diagnosed juvenile idiopathic arthritis.
causal interaction
diagnostic usage
unassigned
1
1
0
Arthritis, Psoriatic
Cleaved N-terminal histone tails distinguish between NADPH oxidase (NOX)-dependent and NOX-independent pathways of neutrophil extracellular trap formation.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
1
1
0
Arthritis, Reactive
Anti-lactoferrin antibodies and other types of anti-neutrophil cytoplasmic antibodies (ANCA) in reactive arthritis and ankylosing spondylitis.
diagnostic usage
ongoing research
unassigned
4
4
0
Arthritis, Rheumatoid
Inhibition of myeloperoxidase by synovial fluid and serum.
causal interaction
diagnostic usage
unassigned
4
3
0
Arthritis, Rheumatoid
Antineutrophil cytoplasmic antibodies and antibodies to myeloperoxidase in rheumatoid arthritis.
diagnostic usage
ongoing research
therapeutic application
unassigned
3
2
1
0
Arthritis, Rheumatoid
[The cytochemical characteristics of neutrophilic leukocytes in the peripheral blood and synovial fluid of patients with rheumatoid arthritis in the course of treatment]
diagnostic usage
ongoing research
therapeutic application
unassigned
1
1
1
0
Arthritis, Rheumatoid
[The diagnostic information value of determining the cytochemical properties of the neutrophils from the blood and synovial fluid of patients with rheumatoid arthritis and osteoarthrosis deformans]
diagnostic usage
ongoing research
unassigned
3
3
0
Arthritis, Rheumatoid
Immunological detection of myeloperoxidase in synovial fluid from patients with rheumatoid arthritis.
causal interaction
diagnostic usage
ongoing research
unassigned
4
2
4
0
Arthritis, Rheumatoid
The effect of D-penicillamine on myeloperoxidase: formation of compound III and inhibition of the chlorinating activity.
causal interaction
therapeutic application
unassigned
4
2
0
Arthritis, Rheumatoid
The effect of D-penicillamine on human myeloperoxidase, a mechanism for the efficacy of the drug in rheumatoid arthritis.
ongoing research
therapeutic application
unassigned
3
2
0
Arthritis, Rheumatoid
Membrane surface proteinase 3 expression and intracytoplasmic immunoglobulin on neutrophils from patients with ANCA-associated vasculitides.
diagnostic usage
ongoing research
unassigned
4
4
0
Arthritis, Rheumatoid
Anti-myeloperoxidase antibodies in patients with rheumatoid arthritis: prevalence, clinical correlates, and IgG subclass.
ongoing research
unassigned
2
0
Arthritis, Rheumatoid
Myeloperoxidase deficiency in a patient with rheumatoid arthritis: oxygenation and radical activity by phagocytic cells.
causal interaction
diagnostic usage
unassigned
4
1
0
Arthritis, Rheumatoid
NMR studies on human, pathologically changed synovial fluids: role of hypochlorous acid.
causal interaction
diagnostic usage
ongoing research
unassigned
2
1
1
0
Arthritis, Rheumatoid
[Rapidly progressive glomerulonephritis associated with myeloperoxidase specific-antineutrophil cytoplasmic antibody in patients with rheumatoid arthritis : report of three cases]
causal interaction
diagnostic usage
unassigned
2
3
0
Arthritis, Rheumatoid
Circulating myeloperoxidase and anti-myeloperoxidase antibody in patients with vasculitis.
diagnostic usage
ongoing research
therapeutic application
unassigned
2
4
1
0
Arthritis, Rheumatoid
Chronic rheumatoid arthritis complicated by myeloperoxidase antineutrophil cytoplasmic antibody-associated nephritis.
causal interaction
diagnostic usage
therapeutic application
unassigned
2
2
2
0
Arthritis, Rheumatoid
Serum lysozyme: a potential marker of monocyte/macrophage activity in rheumatoid arthritis.
causal interaction
diagnostic usage
ongoing research
unassigned
2
4
2
0
Arthritis, Rheumatoid
The reaction of hyaluronic acid and its monomers, glucuronic acid and N-acetylglucosamine, with reactive oxygen species.
unassigned
0
Arthritis, Rheumatoid
Investigation of protein oxidation and lipid peroxidation in patients with rheumatoid arthritis.
diagnostic usage
ongoing research
unassigned
3
2
0
Arthritis, Rheumatoid
Antineutrophil cytoplasmic antibodies in Bulgarian patients with rheumatoid arthritis: characterization and clinical associations.
diagnostic usage
ongoing research
unassigned
4
4
0
Arthritis, Rheumatoid
Rheumatoid arthritis complicated with myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA)-associated vasculitis: a case report.
causal interaction
unassigned
1
0
Arthritis, Rheumatoid
Antineutrophil cytoplasmic antibodies against myeloperoxidase, proteinase 3, elastase, cathepsin G and lactoferrin in Japanese patients with rheumatoid arthritis.
diagnostic usage
therapeutic application
unassigned
2
1
0
Arthritis, Rheumatoid
Clinical proteomics in chronic inflammatory diseases: A review.
diagnostic usage
therapeutic application
unassigned
4
1
0
Arthritis, Rheumatoid
Increased myeloperoxidase plasma levels in rheumatoid arthritis.
causal interaction
diagnostic usage
unassigned
4
4
0
Arthritis, Rheumatoid
Myeloperoxidase and oxidative stress in rheumatoid arthritis.
causal interaction
ongoing research
unassigned
4
3
0
Arthritis, Rheumatoid
High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis.
causal interaction
diagnostic usage
unassigned
4
1
0
Arthritis, Rheumatoid
Myeloperoxidase and its products in synovial fluid of patients with treated or untreated rheumatoid arthritis.
causal interaction
diagnostic usage
ongoing research
therapeutic application
3
4
2
3
Arthritis, Rheumatoid
Simultaneous automated screening and confirmatory testing for vasculitis-specific ANCA.
diagnostic usage
therapeutic application
unassigned
1
1
0
Arthritis, Rheumatoid
Increased levels of serum myeloperoxidase in patients with active rheumatoid arthritis.
causal interaction
diagnostic usage
unassigned
4
4
0
Arthritis, Rheumatoid
Direct and indirect pathogenic roles of autoantibodies in systemic autoimmune diseases.
unassigned
0
Arthritis, Rheumatoid
Methods for measuring myeloperoxidase activity toward assessing inhibitor efficacy in living systems.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
2
4
0
Arthritis, Rheumatoid
Rheumatoid arthritis antigens homocitrulline and citrulline are generated by local myeloperoxidase and peptidyl arginine deiminases 2, 3 and 4 in rheumatoid nodule and synovial tissue.
causal interaction
ongoing research
therapeutic application
unassigned
1
4
1
0
Arthritis, Rheumatoid
Hepatic Proteins and Inflammatory Markers in Rheumatoid Arthritis Patients.
causal interaction
ongoing research
unassigned
2
4
0
Arthritis, Rheumatoid
Cleaved N-terminal histone tails distinguish between NADPH oxidase (NOX)-dependent and NOX-independent pathways of neutrophil extracellular trap formation.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
1
1
0
Arthritis, Rheumatoid
Activated neutrophil carbamylates albumin via the release of myeloperoxidase and reactive oxygen species regardless of NETosis.
diagnostic usage
ongoing research
unassigned
4
2
0
Arthus Reaction
Immune complexes and inflammation. A study of the activity of anti-inflammatory drugs in the reverse passive arthus reaction in the rat.
unassigned
0
Asbestosis
Increased alveolar nitric oxide concentration and high levels of leukotriene B(4) and 8-isoprostane in exhaled breath condensate in patients with asbestosis.
causal interaction
diagnostic usage
unassigned
3
3
0
Ascorbic Acid Deficiency
Phagocytosis and leukocyte enzymes in ascorbic acid deficient guinea pigs.
unassigned
0
Aspergillosis
Neutrophils differentially attenuate immune response to Aspergillus infection through complement receptor 3 and induction of myeloperoxidase.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
1
3
3
Asthma
Blood eosinophil number and activity in relation to lung function in patients with asthma and with eosinophilia.
therapeutic application
unassigned
1
0
Asthma
Eosinophil cationic protein in nasal secretion and in serum and myeloperoxidase in serum in respiratory syncytial virus bronchiolitis: relation to asthma and atopy.
causal interaction
diagnostic usage
ongoing research
therapeutic application
2
4
2
1
Asthma
Eosinophil cationic protein, myeloperoxidase and tryptase in children with asthma and atopic dermatitis.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
3
1
1
Asthma
Plasma protein leakage and local secretion of proteins assessed in sputum in asthma and COPD. The effect of inhaled corticosteroids.
causal interaction
unassigned
4
0
Asthma
Interleukin-8 in airway inflammation in patients with asthma and chronic obstructive pulmonary disease.
causal interaction
diagnostic usage
unassigned
3
3
0
Asthma
Urinary eosinophil protein X in children with atopic asthma: a useful marker of antiinflammatory treatment.
diagnostic usage
unassigned
3
0
Asthma
Granulocyte proteins in serum in childhood asthma: relation to spirometry and therapy.
diagnostic usage
ongoing research
unassigned
3
2
0
Asthma
Granulocyte activation markers in induced sputum: comparison between chronic obstructive pulmonary disease, asthma, and normal subjects.
ongoing research
unassigned
3
0
Asthma
Asthma, bronchial hyperreactivity and mediator release in children with birch pollinosis. ECP and EPX levels are not related to bronchial hyperreactivity.
unassigned
0
Asthma
Markers of airway inflammation in preschool wheezers.
causal interaction
diagnostic usage
unassigned
4
4
0
Asthma
Stimulated salivary flow rate and composition in asthmatic and non-asthmatic adults.
ongoing research
unassigned
2
0
Asthma
Serum inflammatory markers and effects of age and tobacco smoke exposure in young non-asthmatic children.
causal interaction
therapeutic application
unassigned
2
1
0
Asthma
Assessment of serum myeloperoxidase in children with bronchial asthma.
causal interaction
diagnostic usage
therapeutic application
unassigned
3
4
1
0
Asthma
Neutrophilic inflammation in severe persistent asthma.
causal interaction
unassigned
4
0
Asthma
Serum levels of eosinophilic cationic protein (ECP), myeloperoxidase (MPO), lipid peroxidation products, interleukin (IL)-5 and interferon (IFN)-gamma in children with bronchial asthma at acute asthma attack and remission.
ongoing research
unassigned
2
0
Asthma
Serum ECP and MPO are increased during exacerbations of chronic bronchitis with airway obstruction.
causal interaction
diagnostic usage
therapeutic application
unassigned
3
2
1
0
Asthma
Bronchoalveolar lavage in asthmatic children: evidence of neutrophil activation in mild-to-moderate persistent asthma.
ongoing research
therapeutic application
unassigned
2
1
0
Asthma
Effect of physical and chemical methods of homogenization on inflammatory mediators in sputum of asthma patients.
diagnostic usage
ongoing research
therapeutic application
unassigned
2
3
1
0
Asthma
Cough, airway inflammation, and mild asthma exacerbation.
ongoing research
therapeutic application
unassigned
1
1
0
Asthma
Association of forced expiratory volume with disease duration and sputum neutrophils in chronic asthma.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
3
1
0
Asthma
Relationship between cough, cough receptor sensitivity and asthma in children.
therapeutic application
unassigned
1
0
Asthma
Adenosine as a Modulator of Functional Activity of Peripheral Blood Phagocytes in Asthmatic Patients and Healthy Volunteers.
therapeutic application
unassigned
1
0
Asthma
Possible anti-inflammatory effect of salmeterol against interleukin-8 and neutrophil activation in asthma in vivo.
causal interaction
ongoing research
unassigned
2
2
0
Asthma
Oxidative and nitrosative events in asthma.
causal interaction
therapeutic application
unassigned
2
1
0
Asthma
Iron, nitric oxide, and myeloperoxidase in asthmatic patients.
causal interaction
diagnostic usage
ongoing research
unassigned
4
4
3
0
Asthma
A testing framework for identifying susceptibility genes in the presence of epistasis.
ongoing research
therapeutic application
unassigned
2
1
0
Asthma
Melatonin is a potent inhibitor for myeloperoxidase.
causal interaction
therapeutic application
unassigned
4
1
0
Asthma
Genetic variation of myeloperoxidase gene contributes to atopic asthma susceptibility: a preliminary association study in Russian population.
diagnostic usage
ongoing research
unassigned
2
4
0
Asthma
Functional variants in the catalase and myeloperoxidase genes, ambient air pollution, and respiratory-related school absences: an example of epistasis in gene-environment interactions.
diagnostic usage
unassigned
2
0
Asthma
Serum myeloperoxidase in wheezing infants: no association with later asthma.
causal interaction
unassigned
4
0
Asthma
Leukocyte peroxidase and leptin: an associated link of glycemic tolerance and bronchial asthma?
causal interaction
unassigned
3
0
Asthma
Formation of reactive sulfite-derived free radicals by the activation of human neutrophils: An ESR study.
causal interaction
unassigned
4
0
Asthma
Churg-Strauss syndrome presenting with acute kidney injury in a case of primary focal segmental glomerulosclerosis.
causal interaction
ongoing research
unassigned
2
1
0
Asthma
Sulfite-mediated oxidation of myeloperoxidase to a free radical: Immuno-spin trapping detection in human neutrophils.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
2
1
0
Asthma
[A case of Churg-Strauss syndrome with short duration from the onset of asthma to diagnosis of vasculitis].
diagnostic usage
ongoing research
unassigned
1
1
0
Asthma
Differences in plasma and sputum biomarkers between COPD and COPD-asthma overlap.
ongoing research
therapeutic application
unassigned
3
1
0
Asthma
Effect of Antibiotics on Polymorphonuclear Leukocyte Functions and Myeloperoxidase Activity, Glutathione and Malondialdehyde Levels in Allergic Asthma.
ongoing research
therapeutic application
unassigned
4
1
0
Asthma
Multidimensional endotyping in patients with severe asthma reveals inflammatory heterogeneity in matrix metalloproteinases and chitinase 3-like protein 1.
causal interaction
ongoing research
unassigned
3
1
0
Asthma
Inflammatory Pattern of the Bronchial Mucosa in Patients with Asthma with Airway Hyperresponsiveness to Hypoosmotic Stimulus.
causal interaction
unassigned
4
0
Asthma
Autoimmune hepatitis and eosinophilic granulomatosis with polyangiitis: a rare association.
diagnostic usage
therapeutic application
unassigned
2
1
0
Asthma
Relationship between Fractional Exhaled Nitric Oxide Level and Efficacy of Inhaled Corticosteroid in Asthma-COPD Overlap Syndrome Patients with Different Disease Severity.
diagnostic usage
ongoing research
unassigned
3
2
0
Asthma
Participation of Antidiuretic Hormone (ADH) in Asthma Exacerbations Induced by Psychological Stress via PKA/PKC Signal Pathway in Airway-Related Vagal Preganglionic Neurons (AVPNs).
causal interaction
diagnostic usage
ongoing research
therapeutic application
3
4
4
1
Asthma
A Role of the ABCC4 Gene Polymorphism in Airway Inflammation of Asthmatics.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
4
4
1
Asthma
Adiponectin alleviates exacerbation of airway inflammation and oxidative stress in obesity-related asthma mice partly through AMPK signaling pathway.
causal interaction
ongoing research
therapeutic application
unassigned
2
3
2
0
Asthma
Sulforaphane treatment reverses corticosteroid resistance in a mixed granulocytic mouse model of asthma by upregulation of antioxidants and attenuation of Th17 immune responses in the airways.
causal interaction
therapeutic application
unassigned
3
3
0
Asthma
Asthma control in eosinophilic granulomatosis with polyangiitis treated with rituximab.
therapeutic application
unassigned
1
0
Asthma
Concurrence of elevated FeNO and airway hyperresponsiveness in nonasthmatic adolescents.
diagnostic usage
unassigned
2
0
Ataxia Telangiectasia
[A spectrophotometric method of determining the myeloperoxidase activity in phagocytic cells]
causal interaction
diagnostic usage
unassigned
4
4
0
Atherosclerosis
[Indicators of lipid peroxidation in the blood in hereditary predisposition to arteriosclerosis]
causal interaction
ongoing research
unassigned
3
3
0
Atherosclerosis
[Myeloperoxidase of neutrophils and its possible role in lipid peroxidation processes in arteriosclerosis]
diagnostic usage
ongoing research
therapeutic application
unassigned
2
3
1
0
Atherosclerosis
Radical acetoacetate oxidation by myeloperoxidase, lactoperoxidase, prostaglandin synthetase, and prostacyclin synthetase: implications for atherosclerosis.
causal interaction
therapeutic application
unassigned
1
3
0
Atherosclerosis
Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions.
causal interaction
diagnostic usage
ongoing research
unassigned
3
2
4
0
Atherosclerosis
Cholesterol chlorohydrin synthesis by the myeloperoxidase-hydrogen peroxide-chloride system: potential markers for lipoproteins oxidatively damaged by phagocytes.
causal interaction
therapeutic application
unassigned
4
3
0
Atherosclerosis
Mechanisms of oxidative damage by myeloperoxidase in atherosclerosis and other inflammatory disorders.
causal interaction
therapeutic application
unassigned
4
1
0
Atherosclerosis
Nitrogen dioxide radical generated by the myeloperoxidase-hydrogen peroxide-nitrite system promotes lipid peroxidation of low density lipoprotein.
therapeutic application
unassigned
1
0
Atherosclerosis
Pathways of phospholipid oxidation by HOCl in human LDL detected by LC-MS.
causal interaction
unassigned
4
0
Atherosclerosis
Kinetics of chlorination of monochlorodimedone by myeloperoxidase.
causal interaction
unassigned
1
0
Atherosclerosis
Comparison of HOCl traps with myeloperoxidase inhibitors in prevention of low density lipoprotein oxidation.
ongoing research
unassigned
1
0
Atherosclerosis
Myeloperoxidase binds to low-density lipoprotein: potential implications for atherosclerosis.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
2
3
0
Atherosclerosis
Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes.
causal interaction
ongoing research
unassigned
1
3
0
Atherosclerosis
Human neutrophils employ the myeloperoxidase/hydrogen peroxide/chloride system to oxidatively damage apolipoprotein A-I.
causal interaction
unassigned
1
0
Atherosclerosis
Association between myeloperoxidase levels and risk of coronary artery disease.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
4
1
0
Atherosclerosis
Correlation between intima-to-media ratio, apolipoprotein B-100, myeloperoxidase, and hypochlorite-oxidized proteins in human atherosclerosis.
causal interaction
ongoing research
unassigned
4
2
0
Atherosclerosis
Generation of intramolecular and intermolecular sulfenamides, sulfinamides, and sulfonamides by hypochlorous acid: a potential pathway for oxidative cross-linking of low-density lipoprotein by myeloperoxidase.
diagnostic usage
unassigned
1
0
Atherosclerosis
Vitamin C protects against hypochlorous Acid-induced glutathione depletion and DNA base and protein damage in human vascular smooth muscle cells.
unassigned
0
Atherosclerosis
The reactions of hypochlorous acid, the reactive oxygen species produced by myeloperoxidase, with lipids.
causal interaction
therapeutic application
unassigned
4
1
0
Atherosclerosis
Effects of hypochlorite and hydrogen peroxide on cardiac autonomic receptors and vascular endothelial function.
causal interaction
therapeutic application
unassigned
2
3
0
Atherosclerosis
Myeloperoxidase polymorphisms in brain infarction. Association with infarct size and functional outcome.
causal interaction
diagnostic usage
therapeutic application
unassigned
2
3
2
0
Atherosclerosis
Myeloperoxidase gene variation as a determinant of atherosclerosis progression in the abdominal and thoracic aorta: an autopsy study.
therapeutic application
unassigned
1
0
Atherosclerosis
Myeloperoxidase-derived reactive chlorinating species from human monocytes target plasmalogens in low density lipoprotein.
causal interaction
therapeutic application
unassigned
4
2
0
Atherosclerosis
Effect of long-term hormone replacement therapy on atherosclerosis progression in postmenopausal women relates to myeloperoxidase promoter polymorphism.
ongoing research
therapeutic application
unassigned
3
3
0
Atherosclerosis
Peroxisome proliferator-activated receptor gamma ligands regulate myeloperoxidase expression in macrophages by an estrogen-dependent mechanism involving the -463GA promoter polymorphism.
causal interaction
therapeutic application
unassigned
4
1
0
Atherosclerosis
Pathogenic factors in vascular dementia and Alzheimer's disease. Multiple actions of heparin that probably are beneficial.
causal interaction
unassigned
1
0
Atherosclerosis
Oxidative modification of low-density lipoprotein: lipid peroxidation by myeloperoxidase in the presence of nitrite.
causal interaction
unassigned
1
0
Atherosclerosis
The role of myeloperoxidase in the pathogenesis of coronary artery disease.
causal interaction
unassigned
4
0
Atherosclerosis
Human myeloperoxidase: a potential target for molecular MR imaging in atherosclerosis.
causal interaction
ongoing research
therapeutic application
unassigned
4
1
4
0
Atherosclerosis
Does mercury promote lipid peroxidation? An in vitro study concerning mercury, copper, and iron in peroxidation of low-density lipoprotein.
diagnostic usage
ongoing research
unassigned
3
2
0
Atherosclerosis
Cocoa polyphenols and inflammatory mediators.
causal interaction
therapeutic application
unassigned
1
1
0
Atherosclerosis
Probucol protects against hypochlorite-induced endothelial dysfunction: identification of a novel pathway of probucol oxidation to a biologically active intermediate.
causal interaction
unassigned
3
0
Atherosclerosis
Thematic review series: The immune system and atherogenesis. Lipoprotein-associated inflammatory proteins: markers or mediators of cardiovascular disease?
causal interaction
therapeutic application
unassigned
4
1
0
Atherosclerosis
The use of myeloperoxidase as a risk marker for atherosclerosis.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
4
4
0
Atherosclerosis
Effect of inhibitors of myeloperoxidase on the development of aortic atherosclerosis in an animal model.
causal interaction
ongoing research
therapeutic application
unassigned
2
3
4
0
Atherosclerosis
Expression of human myeloperoxidase by macrophages promotes atherosclerosis in mice.
causal interaction
ongoing research
unassigned
3
4
0
Atherosclerosis
Biosynthesis, processing, and sorting of human myeloperoxidase.
causal interaction
unassigned
3
0
Atherosclerosis
Myeloperoxidase genetic polymorphisms modulate human neutrophil enzyme activity: genetic determinants for atherosclerosis?
causal interaction
therapeutic application
unassigned
1
1
0
Atherosclerosis
Myeloperoxidase activity imaging using (67)Ga labeled substrate.
ongoing research
therapeutic application
unassigned
1
1
0
Atherosclerosis
Acute neutrophil activation in direct stenting: comparison of stable and unstable angina patients.
causal interaction
diagnostic usage
ongoing research
unassigned
2
4
2
0
Atherosclerosis
Endurance training reduces circulating asymmetric dimethylarginine and myeloperoxidase levels in persons at risk of coronary events.
causal interaction
unassigned
2
0
Atherosclerosis
Myeloperoxidase-derived 2-chlorohexadecanal forms Schiff bases with primary amines of ethanolamine glycerophospholipids and lysine.
causal interaction
therapeutic application
unassigned
4
1
0
Atherosclerosis
Metabolism of myeloperoxidase-derived 2-chlorohexadecanal.
causal interaction
therapeutic application
unassigned
4
1
0
Atherosclerosis
Myeloperoxidase predicts progression of carotid stenosis in states of low high-density lipoprotein cholesterol.
causal interaction
diagnostic usage
ongoing research
unassigned
4
3
2
0
Atherosclerosis
Development of an ELISA for myeloperoxidase on microplate: Normal reference values and effect of temperature on specimen preparation.
causal interaction
unassigned
4
0
Atherosclerosis
The human myeloperoxidase gene is regulated by LXR and PPARalpha ligands.
causal interaction
unassigned
4
0
Atherosclerosis
Heparin, myeloperoxidase, and atherosclerosis: a new focus on an old drug.
therapeutic application
unassigned
4
0
Atherosclerosis
A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages.
causal interaction
unassigned
3
0
Atherosclerosis
Atherosclerosis and oxidative stress.
causal interaction
unassigned
4
0
Atherosclerosis
The role of myeloperoxidase in HDL oxidation and atherogenesis.
ongoing research
unassigned
2
0
Atherosclerosis
Postprandial serum induces apoptosis in endothelial cells: Role of polymorphonuclear-derived myeloperoxidase and metalloproteinase-9 activity.
causal interaction
unassigned
4
0
Atherosclerosis
Melatonin is a potent inhibitor for myeloperoxidase.
causal interaction
therapeutic application
unassigned
4
1
0
Atherosclerosis
The association of myeloperoxidase promoter polymorphism with carotid atherosclerosis is abolished in patients with type 2 diabetes.
causal interaction
ongoing research
therapeutic application
unassigned
1
3
1
0
Atherosclerosis
Diabetes mellitus type 2 is associated with higher levels of myeloperoxidase.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
3
2
0
Atherosclerosis
A sensitive and specific ELISA detects methionine sulfoxide-containing apolipoprotein A-I in HDL.
causal interaction
unassigned
2
0
Atherosclerosis
Myeloperoxidase, modified lipoproteins, and atherogenesis.
causal interaction
ongoing research
therapeutic application
unassigned
2
2
1
0
Atherosclerosis
Combined effect of oxidative stress-related gene polymorphisms on atherosclerosis.
ongoing research
unassigned
2
0
Atherosclerosis
Usefulness of serum myeloperoxidase in prediction of mortality in patients with severe heart failure.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
4
1
1
Atherosclerosis
Arterial stiffness, carotid artery intima-media thickness and plasma myeloperoxidase level in children with type 1 diabetes.
causal interaction
diagnostic usage
ongoing research
unassigned
3
4
4
0
Atherosclerosis
Bioluminescence imaging of myeloperoxidase activity in vivo.
causal interaction
therapeutic application
unassigned
1
1
0
Atherosclerosis
Dysfunctional high-density lipoprotein.
unassigned
0
Atherosclerosis
Hypochlorous acid-induced heme oxygenase-1 gene expression promotes human endothelial cell survival.
causal interaction
unassigned
1
0
Atherosclerosis
Enzyme-sensitive magnetic resonance imaging targeting myeloperoxidase identifies active inflammation in experimental rabbit atherosclerotic plaques.
causal interaction
unassigned
2
0
Atherosclerosis
Coronary stenting is associated with an acute increase in plasma myeloperoxidase in stable angina patients but not in patients with acute myocardial infarction.
causal interaction
diagnostic usage
ongoing research
unassigned
4
4
2
0
Atherosclerosis
Myeloperoxidase, subclinical atherosclerosis, and cardiovascular disease events.
diagnostic usage
ongoing research
therapeutic application
unassigned
4
4
3
0
Atherosclerosis
Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan.
causal interaction
therapeutic application
unassigned
4
1
0
Atherosclerosis
Serial Analyses of C-Reactive Protein and Myeloperoxidase in Acute Coronary Syndrome.
causal interaction
diagnostic usage
unassigned
3
3
0
Atherosclerosis
Inflammatory mediators and premature coronary atherosclerosis in rheumatoid arthritis.
causal interaction
unassigned
4
0
Atherosclerosis
Prognostic value of myeloperoxidase in coronary artery disease: comparison of unstable and stable angina patients.
causal interaction
diagnostic usage
ongoing research
unassigned
4
4
1
0
Atherosclerosis
Elevated MMP-8 and decreased myeloperoxidase concentrations associate significantly with the risk for peripheral atherosclerosis disease and abdominal aortic aneurysm.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
4
1
0
Atherosclerosis
Prognostic value of plasma myeloperoxidase in ESRD patients.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
4
3
2
Atherosclerosis
Benefits of napping and an extended duration of recovery sleep on alertness and immune cells after acute sleep restriction.
diagnostic usage
ongoing research
unassigned
3
1
0
Atherosclerosis
Oenothera paradoxa defatted seeds extract and its bioactive component penta-O-galloyl-?-D-glucose decreased production of reactive oxygen species and inhibited release of leukotriene B4, interleukin-8, elastase, and myeloperoxidase in human neutrophils.
causal interaction
therapeutic application
unassigned
2
2
0
Atherosclerosis
Effect of unsaturation in fatty acids on the binding and oxidation by myeloperoxidase: ramifications for the initiation of atherosclerosis.
causal interaction
ongoing research
therapeutic application
unassigned
1
2
1
0
Atherosclerosis
Diagnostic value of MPO plasma levels in patients admitted for suspected myocardial infarction.
causal interaction
diagnostic usage
unassigned
4
1
0
Atherosclerosis
[Markers of chloric acid (I) in biological systems--identification and properties].
causal interaction
ongoing research
unassigned
4
1
0
Atherosclerosis
Novel biomarkers in cardiovascular disease: update 2010.
causal interaction
diagnostic usage
ongoing research
unassigned
3
2
2
0
Atherosclerosis
MPO and neutrophils: a magnetic attraction.
causal interaction
therapeutic application
unassigned
2
1
0
Atherosclerosis
The effect on serum myeloperoxidase activity and oxidative status of eradication treatment in patients Helicobacter pylori infected.
causal interaction
therapeutic application
unassigned
4
4
0
Atherosclerosis
The ARIC Carotid MRI Study of Blood Cellular Markers: An Inverse Association of Monocyte Myeloperoxidase Content With Peripheral Arterial Disease.
diagnostic usage
ongoing research
unassigned
2
3
0
Atherosclerosis
Role of VPO1, a newly identified heme-containing peroxidase, in ox-LDL induced endothelial cell apoptosis.
causal interaction
therapeutic application
unassigned
4
1
0
Atherosclerosis
High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase.
causal interaction
diagnostic usage
therapeutic application
unassigned
3
2
1
0
Atherosclerosis
Race-specific associations of myeloperoxidase with atherosclerosis in a population-based sample: the Dallas Heart Study.
causal interaction
ongoing research
therapeutic application
unassigned
4
2
1
0
Atherosclerosis
Advanced oxidation protein products and advanced glycation end products in children and adolescents with chronic renal insufficiency.
diagnostic usage
unassigned
1
0
Atherosclerosis
Myeloperoxidase Production by Macrophage and Risk of Atherosclerosis.
causal interaction
therapeutic application
unassigned
2
1
0
Atherosclerosis
Serum myeloperoxidase activity and oxidative stress in patients with acute brucellosis.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
4
4
1
Atherosclerosis
Serum myeloperoxidase is independent of the risk factors of atherosclerosis.
causal interaction
diagnostic usage
unassigned
4
4
0
Atherosclerosis
High plasma thiocyanate levels modulate protein damage induced by myeloperoxidase and perturb measurement of 3-chlorotyrosine.
causal interaction
diagnostic usage
unassigned
4
1
0
Atherosclerosis
In vivo examination of 111In-bis-5HT-DTPA to target myeloperoxidase in atherosclerotic ApoE knockout mice.
causal interaction
ongoing research
therapeutic application
unassigned
2
2
1
0
Atherosclerosis
Protein thiol oxidation and formation of S-glutathionylated cyclophilin A in cells exposed to chloramines and hypochlorous acid.
causal interaction
therapeutic application
unassigned
3
1
0
Atherosclerosis
Effects of a novel pharmacologic inhibitor of myeloperoxidase in a mouse atherosclerosis model.
causal interaction
ongoing research
therapeutic application
unassigned
4
4
4
0
Atherosclerosis
The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings.
causal interaction
therapeutic application
unassigned
4
1
0
Atherosclerosis
Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex.
causal interaction
unassigned
2
0
Atherosclerosis
Myeloperoxidase levels predict accelerated progression of coronary atherosclerosis in diabetic patients: insights from intravascular ultrasound.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
2
1
0
Atherosclerosis
Impact of myeloperoxidase-LDL interactions on enzyme activity and subsequent posttranslational oxidative modifications of apoB-100.
causal interaction
therapeutic application
unassigned
1
1
0
Atherosclerosis
Humans with Atherosclerosis have Impaired ABCA1 Cholesterol Efflux and Enhanced HDL Oxidation by Myeloperoxidase.
unassigned
0
Atherosclerosis
Niacin decreases leukocyte myeloperoxidase: mechanistic role of redox agents and Src/p38MAP kinase.
causal interaction
therapeutic application
unassigned
4
1
0
Atherosclerosis
Alpha-chlorofatty Acid and coronary artery or aorta calcium scores in women with systemic lupus erythematosus. A pilot study.
causal interaction
therapeutic application
unassigned
1
1
0
Atherosclerosis
Paraoxonase 1 and HDL maturation.
causal interaction
therapeutic application
unassigned
3
2
0
Atherosclerosis
Shift of the interconnection from the reaction system of paraoxonase 1 to the peroxidation reaction system of myeloperoxidase with HDL-C levels: a marker of atherosclerosis in patients with normal cholesterol levels.
diagnostic usage
ongoing research
unassigned
4
1
0
Atherosclerosis
Therapeutic Potential of Ocimum tenuiflorum as MPO Inhibitor with Implications for Atherosclerosis Prevention.
causal interaction
unassigned
4
0
Atherosclerosis
[Role of protein carbamylation in chronic kidney disease complications].
causal interaction
unassigned
1
0
Atherosclerosis
Comparative reactivity of the myeloperoxidase-derived oxidants HOCl and HOSCN with low-density lipoprotein (LDL): Implications for foam cell formation in atherosclerosis.
causal interaction
unassigned
4
0
Atherosclerosis
Bilirubin scavenges chloramines and inhibits myeloperoxidase-induced protein/lipid oxidation in physiologically relevant hyperbilirubinemic serum.
causal interaction
unassigned
1
0
Atherosclerosis
Protective effects of Xiongshao Capsule () on anti-inflammatory function of high-density lipoprotein in atherosclerosis rabbit model.
diagnostic usage
ongoing research
unassigned
1
3
0
Atherosclerosis
Neutrophil-derived myeloperoxidase promotes atherogenesis and neointima formation in mice.
ongoing research
unassigned
2
0
Atherosclerosis
Paraoxonase-1 arylesterase activity is an independent predictor of myeloperoxidase levels in overweight patients with or without cardiovascular complications.
causal interaction
ongoing research
therapeutic application
unassigned
4
3
4
0
Atherosclerosis
Validation of a sensitive LC/MSMS method for chloronucleoside analysis in biological matrixes and its applications.
causal interaction
unassigned
4
0
Atherosclerosis
Detailed protocol to assess in vivo and ex vivo myeloperoxidase activity in mouse models of vascular inflammation and disease using hydroethidine.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
2
1
0
Atherosclerosis
Development of Monoclonal Antibody against Chlorinated 192 Tyrosine Containing ApoAI Peptide to Screen Quality of Human High Density Lipoprotein (HDL).
causal interaction
therapeutic application
unassigned
1
1
0
Atherosclerosis
The roles of myeloperoxidase in coronary artery disease and its potential implication in plaque rupture.
causal interaction
diagnostic usage
ongoing research
unassigned
4
1
1
0
Atherosclerosis
The presence of modified nucleosides in extracellular fluids leads to the specific incorporation of 5-chlorocytidine into RNA and modulates the transcription and translation.
causal interaction
therapeutic application
unassigned
4
1
0
Atherosclerosis
Evidence that endogenous formaldehyde produces immunogenic and atherogenic adduct epitopes.
ongoing research
unassigned
2
0
Atherosclerosis
Myeloperoxidase: A promising therapeutic target in prevention of atherosclerosis.
causal interaction
therapeutic application
unassigned
4
4
0
Atherosclerosis
Chlorinative stress in age-related diseases: a literature review.
causal interaction
therapeutic application
unassigned
4
1
0
Atherosclerosis
A pivotal role for NF-?B in the macrophage inflammatory response to the myeloperoxidase oxidant hypothiocyanous acid.
unassigned
0
Atherosclerosis
Inhibition of myeloperoxidase might be a novel therapeutic target in the treatment of atherosclerosis.
causal interaction
therapeutic application
unassigned
4
4
0
Atherosclerosis
Myeloperoxidase derived oxidants damage artery wall proteins in an animal model of chronic kidney disease accelerated atherosclerosis.
causal interaction
ongoing research
unassigned
4
3
0
Atherosclerosis
Serum markers for asymptomatic atherosclerosis in Egyptian psoriatic patients: study controlled by Doppler estimation of carotid intima-media thickness.
diagnostic usage
ongoing research
unassigned
2
2
0
Atherosclerosis
Neutrophil elastase and myeloperoxidase mRNA expression in overweight and obese subjects.
causal interaction
diagnostic usage
unassigned
4
3
0
Atherosclerosis
Triazolopyrimidines identified as reversible myeloperoxidase inhibitors.
causal interaction
therapeutic application
unassigned
3
4
0
Atherosclerosis
Targeting myeloperoxidase in inflammatory atherosclerosis.
causal interaction
therapeutic application
unassigned
4
3
0
Atherosclerosis
Association of monocyte myeloperoxidase with incident cardiovascular disease: The Atherosclerosis Risk in Communities Study.
causal interaction
ongoing research
unassigned
3
2
0
Atherosclerosis
Association of myeloperoxidase with cardiovascular disease risk factors in prediabetic subjects.
causal interaction
unassigned
4
0
Atherosclerosis
Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells.
causal interaction
unassigned
2
0
Atherosclerosis
Measurements for Sulfide-Mediated Inhibition of Myeloperoxidase Activity.
therapeutic application
unassigned
1
0
Atherosclerosis
8-Chloroadenosine induces apoptosis in human coronary artery endothelial cells through the activation of the unfolded protein response.
causal interaction
unassigned
4
0
Atherosclerosis
Microarray and proteome array in an atherosclerosis mouse model for identification of biomarkers in whole blood.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
4
2
0
Atherosclerosis
Development of anti-chloro 192 tyrosine HDL apoA-I antibodies for the immunodiagnosis of cardiovascular diseases.
causal interaction
unassigned
1
0
Atherosclerosis
Linking myeloperoxidase with subclinical atherosclerosis in adults with metabolic syndrome.
causal interaction
diagnostic usage
ongoing research
therapeutic application
3
4
3
2
Atherosclerosis
Potential clinical utility of macrophage colony-stimulating factor, monocyte chemotactic protein-1 and myeloperoxidase in predicting atherosclerotic plaque instability.
causal interaction
diagnostic usage
ongoing research
unassigned
2
1
2
0
Atrial Fibrillation
The onset of Graves' disease during the clinical course of myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA)-associated glomerulonephritis.
diagnostic usage
ongoing research
therapeutic application
unassigned
1
2
1
0
Atrial Fibrillation
Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation.
diagnostic usage
ongoing research
therapeutic application
unassigned
1
2
2
0
Atrial Fibrillation
Myeloperoxidase and risk of recurrence of atrial fibrillation after catheter ablation.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
2
3
0
Atrial Fibrillation
Effects of atorvastatin on atrial remodeling in a rabbit model of atrial fibrillation produced by rapid atrial pacing.
causal interaction
unassigned
4
0
Atrial Fibrillation
Myeloperoxidase in atrial fibrillation: association with progression, origin and influence of renin-angiotensin system antagonists.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
2
1
0
Autoimmune Diseases
Autoantibodies to myeloperoxidase in brown Norway rats treated with mercuric chloride.
causal interaction
therapeutic application
unassigned
4
1
0
Autoimmune Diseases
Brother and sister with myeloperoxidase associated autoimmune disease.
causal interaction
unassigned
4
0
Autoimmune Diseases
Antineutrophil cytoplasmic autoantibody testing in vasculitides.
causal interaction
unassigned
1
0
Autoimmune Diseases
Antibodies to myeloperoxidase in propylthiouracil-induced autoimmune disease in the cat.
diagnostic usage
unassigned
2
0
Autoimmune Diseases
Myeloperoxidase autoantibodies distinguish vasculitis mediated by anti-neutrophil cytoplasm antibodies from immune complex disease in MRL/Mp-lpr/lpr mice: a spontaneous model for human microscopic angiitis.
causal interaction
diagnostic usage
ongoing research
unassigned
2
2
4
0
Autoimmune Diseases
The clinical features and pathology of vasculitis associated with anti-myeloperoxidase autoantibodies.
causal interaction
diagnostic usage
unassigned
4
1
0
Autoimmune Diseases
Trojan horses: drug culprits associated with antineutrophil cytoplasmic autoantibody (ANCA) vasculitis.
causal interaction
unassigned
2
0
Autoimmune Diseases
Discrepancies between two immunoassays for the determination of MPO and PR3 autoantibodies.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
3
1
0
Babesiosis
Neutrophil Myeloperoxidase Index in Dogs With Babesiosis Caused by Babesia rossi.
therapeutic application
unassigned
1
0
Bacteremia
Reduced neutrophil sequestration in lung tissue after laparoscopic lavage in a rat peritonitis model.
diagnostic usage
ongoing research
therapeutic application
unassigned
4
2
1
0
Bacteremia
IV Immunoglobulin for Acute Lung Injury and Bacteremia in Pseudomonas aeruginosa Pneumonia.
diagnostic usage
ongoing research
therapeutic application
unassigned
3
3
1
0
Bacteremia
The Adaptor Protein Myd88 Is a Key Signaling Molecule in the Pathogenesis of Irinotecan-Induced Intestinal Mucositis.
causal interaction
diagnostic usage
ongoing research
unassigned
2
4
2
0
Bacteremia
Fms-Like Tyrosine Kinase-3 Ligand Attenuates Local and Systemic Infection in a Model of Post-Burn Pneumonia.
diagnostic usage
ongoing research
therapeutic application
unassigned
1
1
1
0
Bacterial Infections
Neutrophilic granulocytes in acute bacterial infection. Sequential studies on lysozyme, myeloperoxidase and lactoferrin.
causal interaction
diagnostic usage
ongoing research
unassigned
2
1
4
0
Bacterial Infections
Neutrophil and eosinophil granulocytes in bacterial infection: sequential studies of cellular and serum levels of granule proteins.
causal interaction
diagnostic usage
ongoing research
unassigned
1
1
2
0
Bacterial Infections
Neutrophil myeloperoxidase concentration: changes with development and during bacterial infection.
causal interaction
ongoing research
unassigned
1
3
0
Bacterial Infections
Neutrophil dysfunction and increased susceptibility to infection.
causal interaction
ongoing research
therapeutic application
unassigned
4
3
1
0
Bacterial Infections
The differential release of eosinophil granule proteins. Studies on patients with acute bacterial and viral infections.
causal interaction
diagnostic usage
ongoing research
unassigned
3
3
3
0
Bacterial Infections
The influence of intravenous anaesthetics on polymorphonuclear leukocyte function.
therapeutic application
unassigned
1
0
Bacterial Infections
Reevaluating gel-forming mucins' roles in cystic fibrosis lung disease.
unassigned
0
Bacterial Infections
Urokinase-type plasminogen activator receptor plays a role in neutrophil migration during lipopolysaccharide-induced peritoneal inflammation but not during Escherichia coli-induced peritonitis.
causal interaction
ongoing research
therapeutic application
unassigned
2
3
1
0
Bacterial Infections
Effects of omega-3 fatty acids on acute necrotizing pancreatitis in rats.
diagnostic usage
ongoing research
unassigned
2
1
0
Bacterial Infections
cDNA cloning and gene expression pattern following bacterial challenge of peroxinectin in Chinese shrimp Fenneropenaeus chinensis.
causal interaction
diagnostic usage
unassigned
3
1
0
Bacterial Infections
Change in inflammation in out-patient COPD patients from stable phase to a subsequent exacerbation.
causal interaction
unassigned
1
0
Bacterial Infections
Association between the neutrophil myeloperoxidase index and subsets of bacterial infections.
causal interaction
diagnostic usage
unassigned
1
4
0
Bacterial Infections
A1M/?1-microglobulin is proteolytically activated by myeloperoxidase, binds its heme group and inhibits low density lipoprotein oxidation.
causal interaction
therapeutic application
unassigned
2
1
0
Bacterial Infections
Lipoprotein-associated phospholipase A2, myeloperoxidase and vascular endothelial growth factor - predictors of high vascular risk in respiratory bacterial infections.
causal interaction
diagnostic usage
unassigned
3
4
0
Bacterial Infections
Fishmeal replacement by rice protein concentrate with xylooligosaccharides supplement benefits the growth performance, antioxidant capability and immune responses against Aeromonas hydrophila in blunt snout bream (Megalobrama amblycephala).
causal interaction
diagnostic usage
unassigned
4
3
0
Barrett Esophagus
Simultaneous progression of oxidative stress and angiogenesis in malignant transformation of Barrett esophagus.
ongoing research
unassigned
4
0
Blast Crisis
Hybrid lymphoid blast crisis of chronic myeloid leukemia with both immunoglobulin and T-cell receptor gene rearrangements.
diagnostic usage
unassigned
1
0
Blast Crisis
Cytophotometry of granulocytes in chronic granulocytic leukemia patients. Part I. Cell cycle distribution, S-phase transition and quantitative cytochemistry.
diagnostic usage
ongoing research
unassigned
1
3
0
Blast Crisis
Expression of the myeloperoxidase gene in acute and chronic myeloid leukemias: relationship to the expression of cell cycle-related genes.
causal interaction
diagnostic usage
ongoing research
unassigned
1
3
4
0
Blast Crisis
Ultrastructural study of chronic myeloid leukemia in blast crisis using myeloperoxidase and acid phosphatase reactions.
diagnostic usage
ongoing research
unassigned
1
3
0
Blast Crisis
Eosinophilic blast crisis in a case of chronic myeloid leukaemia.
causal interaction
diagnostic usage
unassigned
4
1
0
Blast Crisis
Myeloperoxidase cytochemical negativity: an unexpected but intrinsic property of blasts of all phases of chronic myeloid leukemia.
causal interaction
diagnostic usage
ongoing research
therapeutic application
1
4
1
1
Blister
Evaluation of the effect of azapropazone on neutrophil migration in anaesthetized swine using a multichamber blister suction technique.
unassigned
0
Blister
8;21 Translocation in acute myeloid leukemia. An ultrastructural study.
diagnostic usage
unassigned
3
0
Blister
Inhibitory effect of KBT-3022, a new anti-platelet agent, on infiltration of polymorphonuclear leukocytes induced by leukotriene B4 or formyl-methionyl-leucyl-phenylalanine in mice.
diagnostic usage
ongoing research
therapeutic application
unassigned
1
2
2
0
Blister
Granulocyte activation in bullous diseases: release of granular proteins in bullous pemphigoid and pemphigus vulgaris.
diagnostic usage
ongoing research
unassigned
4
2
0
Blister
Increased tryptase and myeloperoxidase levels in blister fluids of patients with bullous pemphigoid: correlations with cytokines, adhesion molecules and anti-basement membrane zone antibodies.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
1
1
0
Blister
Nonlethal oxidant injury to human retinal pigment epithelium cells causes cell membrane blebbing but decreased MMP-2 activity.
causal interaction
diagnostic usage
ongoing research
unassigned
2
1
4
0
Blister
Functionally active macrophage-derived myeloperoxidase in the skin of drug-induced toxic epidermal necrolysis.
diagnostic usage
ongoing research
therapeutic application
unassigned
2
2
1
0
Blister
Marked hyperphosphatasemia associated with an acute leukemia in a Great Dane.
diagnostic usage
therapeutic application
unassigned
4
1
0
Bone Resorption
The effect of dichloromethylene bisphosphonate on human gingival crevicular neutrophil myeloperoxidase activity.
ongoing research
unassigned
4
0
Bone Resorption
Therapeutic Effects of Melatonin on Alveolar Bone Resorption After Experimental Periodontitis in Rats: A Biochemical and Immunohistochemical Study.
diagnostic usage
unassigned
3
0
Brain Abscess
The proteome of pus from human brain abscesses: host-derived neurotoxic proteins and the cell-type diversity of CNS pus.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
1
1
0
Brain Death
Amelioration of renal damage by administration of anti-thymocyte globulin to potential donors in a brain death rat model.
causal interaction
unassigned
1
0
Brain Diseases
Development of rapid multistep carbon-11 radiosynthesis of the myeloperoxidase inhibitor AZD3241 to assess brain exposure by PET microdosing.
causal interaction
therapeutic application
unassigned
4
4
0
Brain Edema
Multiple actions of the coumarine derivative cloricromene and its protective effects on ischemic brain injury.
diagnostic usage
ongoing research
unassigned
1
2
0
Brain Edema
Changes of MPO activity and brain water accumulation in traumatic brain injury experiments.
diagnostic usage
unassigned
2
0
Brain Edema
Attenuation of brain inflammatory response after focal cerebral ischemia/reperfusion with xuesaitong injection in rats.
diagnostic usage
ongoing research
unassigned
3
2
0
Brain Edema
Effect of Rosiglitazone Maleate on inflammation following cerebral ischemia/reperfusion in rats.
diagnostic usage
ongoing research
unassigned
3
4
0
Brain Edema
Reduced brain injury in CD18-deficient mice after experimental intracerebral hemorrhage.
diagnostic usage
ongoing research
unassigned
3
1
0
Brain Edema
Neuroprotective efficacy and therapeutic window of Forsythoside B: in a rat model of cerebral ischemia and reperfusion injury.
unassigned
0
Brain Edema
Inhibition of leukotriene B4 synthesis protects against early brain injury possibly via reducing the neutrophil-generated inflammatory response and oxidative stress after subarachnoid hemorrhage in rats.
causal interaction
therapeutic application
unassigned
3
4
0
Brain Edema
Recombinant Netrin-1 binding UNC5B receptor attenuates neuroinflammation and brain injury via PPAR?/NF?B signaling pathway after subarachnoid hemorrhage in rats.
causal interaction
therapeutic application
unassigned
3
2
0
Brain Edema
MRI of Iron Oxide Nanoparticles and Myeloperoxidase Activity Links Inflammation to Brain Edema in Experimental Cerebral Malaria.
ongoing research
unassigned
3
0
Brain Infarction
Myeloperoxidase polymorphisms in brain infarction. Association with infarct size and functional outcome.
causal interaction
diagnostic usage
therapeutic application
unassigned
2
3
2
0
Brain Infarction
Ethanol attenuates ischemic and hypoxic injury in rat brain and cultured neurons.
causal interaction
unassigned
3
0
Brain Infarction
Neuroprotective efficacy and therapeutic window of Forsythoside B: in a rat model of cerebral ischemia and reperfusion injury.
unassigned
0
Brain Infarction
Rosmarinic acid prevents against memory deficits in ischemic mice.
diagnostic usage
unassigned
2
0
Brain Infarction
AP-VAS 2012 case report: a case of systemic MPO-ANCA-associated vasculitis that demonstrated brain infarction and immunohistochemically MPO-positive capillaries.
ongoing research
unassigned
2
0
Brain Infarction
NAD replenishment with nicotinamide mononucleotide protects blood-brain barrier integrity and attenuates delayed tissue plasminogen activator-induced haemorrhagic transformation after cerebral ischaemia.
diagnostic usage
unassigned
1
0
Brain Injuries
Changes of MPO activity and brain water accumulation in traumatic brain injury experiments.
diagnostic usage
unassigned
2
0
Brain Injuries
Hyperglycemia triggers massive neutrophil deposition in brain following transient ischemia in rats.
diagnostic usage
ongoing research
therapeutic application
unassigned
2
2
1
0
Brain Injuries
Deficiency of myeloperoxidase increases infarct volume and nitrotyrosine formation in mouse brain.
ongoing research
unassigned
3
0
Brain Injuries
Effects of anti-intercellular adhesion molecule-1 antibody on reperfusion injury induced by late reperfusion in the rat middle cerebral artery occlusion model.
causal interaction
therapeutic application
unassigned
3
1
0
Brain Injuries
Inflammatory cell infiltration after endothelin-1-induced cerebral ischemia: histochemical and myeloperoxidase correlation with temporal changes in brain injury.
ongoing research
unassigned
2
0
Brain Injuries
Decreased myeloperoxidase expressing cells in the aged rat brain after excitotoxic damage.
causal interaction
unassigned
3
0
Brain Injuries
Transplantation of human amniotic mesenchymal stem cells promotes neurological recovery in an intracerebral hemorrhage rat model.
causal interaction
therapeutic application
unassigned
1
1
0
Brain Injuries
Inhibition of Myeloperoxidase by
causal interaction
therapeutic application
unassigned
4
1
0
Brain Injuries, Traumatic
Neutrophil accumulation after traumatic brain injury in rats: comparison of weight drop and controlled cortical impact models.
diagnostic usage
unassigned
3
0
Brain Injuries, Traumatic
Importance of posttraumatic hypothermia and hyperthermia on the inflammatory response after fluid percussion brain injury: biochemical and immunocytochemical studies.
ongoing research
therapeutic application
unassigned
2
1
0
Brain Injuries, Traumatic
AA-861 appears to suppress leukocyte infiltration induced by traumatic brain injury in rats.
diagnostic usage
ongoing research
unassigned
1
3
0
Brain Ischemia
Effects of tempol, a membrane-permeable radical scavenger, in a gerbil model of brain injury.
causal interaction
unassigned
2
0
Brain Ischemia
Protective effects of melatonin in ischemic brain injury.
causal interaction
unassigned
2
0
Brain Ischemia
Neuroprotective effects of hyperbaric oxygen treatment in experimental focal cerebral ischemia are associated with reduced brain leukocyte myeloperoxidase activity.
therapeutic application
unassigned
4
0
Brain Ischemia
Matrix metalloproteinase-9 and myeloperoxidase expression: quantitative analysis by antigen immunohistochemistry in a model of transient focal cerebral ischemia.
diagnostic usage
ongoing research
therapeutic application
unassigned
1
4
1
0
Brain Ischemia
Anti-inflammatory effect of hydroxyethylpuerarin on focal brain ischemia/reperfusion injury in rats.
diagnostic usage
unassigned
2
0
Brain Ischemia
Neuroprotection with the CXCL8 inhibitor repertaxin in transient brain ischemia.
diagnostic usage
therapeutic application
unassigned
2
1
0
Brain Ischemia
Inflammatory cell infiltration after endothelin-1-induced cerebral ischemia: histochemical and myeloperoxidase correlation with temporal changes in brain injury.
ongoing research
unassigned
2
0
Brain Ischemia
Cannabidiol prevents a post-ischemic injury progressively induced by cerebral ischemia via a high-mobility group box1-inhibiting mechanism.
diagnostic usage
therapeutic application
unassigned
2
1
0
Brain Ischemia
Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidase.
causal interaction
therapeutic application
unassigned
2
1
0
Brain Ischemia
Propofol Reduces Inflammatory Reaction and Ischemic Brain Damage in Cerebral Ischemia in Rats.
diagnostic usage
therapeutic application
unassigned
4
1
0
Brain Ischemia
Ischemic preconditioning reduces ischemic brain injury by suppressing nuclear factor kappa B expression and neuronal apoptosis.
causal interaction
therapeutic application
unassigned
4
4
0
Brain Ischemia
Repetitive Ischemic Preconditioning Attenuates Inflammatory Reaction and Brain Damage After Focal Cerebral Ischemia in Rats: Involvement of PI3K/Akt and ERK1/2 Signaling Pathway.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
3
2
1
Brain Ischemia
5-LOX Inhibitor Zileuton Reduces Inflammatory Reaction and Ischemic Brain Damage Through the Activation of PI3K/Akt Signaling Pathway.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
3
2
2
Brain Ischemia
(-)-?-bisabolol prevents neuronal damage and memory deficits through reduction of proinflammatory markers induced by permanent focal cerebral ischemia in mice.
causal interaction
therapeutic application
unassigned
2
1
0
Breast Neoplasms
Enzymatic deficiencies of the immune system cells in patients with cancer of the larynx and other malignancies.
causal interaction
diagnostic usage
ongoing research
unassigned
4
3
2
0
Breast Neoplasms
The role of peroxidase-catalyzed activation of aromatic amines in breast cancer.
causal interaction
unassigned
4
0
Breast Neoplasms
Occult deposition of eosinophil peroxidase in a subset of human breast carcinomas.
diagnostic usage
ongoing research
therapeutic application
unassigned
1
4
1
0
Breast Neoplasms
Amplification units and translocation at chromosome 17q and c-erbB-2 overexpression in the pathogenesis of breast cancer.
unassigned
0
Breast Neoplasms
Myeloperoxidase genotype, fruit and vegetable consumption, and breast cancer risk.
diagnostic usage
therapeutic application
unassigned
1
1
0
Breast Neoplasms
Polymorphisms in genes related to oxidative stress (MPO, MnSOD, CAT) and survival after treatment for breast cancer.
causal interaction
ongoing research
therapeutic application
unassigned
2
1
4
0
Breast Neoplasms
Genetic variants of myeloperoxidase and catechol-O-methyltransferase and breast cancer risk.
diagnostic usage
ongoing research
unassigned
2
3
0
Breast Neoplasms
Polymorphisms in manganese superoxide dismutase, myeloperoxidase and glutathione-S-transferase and survival after treatment for metastatic breast cancer.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
2
4
0
Breast Neoplasms
[The plasma level of sL-selectin, myeloperoxidase and granulocyte-colony stimulating factor (G-CSF) in breast cancer patients in the course of chemotherapy]
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
2
4
1
Breast Neoplasms
Oxidative stress-related genotypes, fruit and vegetable consumption and breast cancer risk.
causal interaction
diagnostic usage
unassigned
2
1
0
Breast Neoplasms
Myeloperoxidase Genotypes and Enhanced Efficacy of Chemotherapy for Early-Stage Breast Cancer in SWOG-8897.
causal interaction
therapeutic application
unassigned
1
4
0
Breast Neoplasms
[The plasma level of sL-selectin, myeloperoxidase (MPO) and granulocyte-colony stimulating factor (G-CSF) in breast cancer patients after surgery]
causal interaction
diagnostic usage
ongoing research
unassigned
1
3
3
0
Breast Neoplasms
Menopausal status modifies breast cancer risk associated with the myeloperoxidase (MPO) G463A polymorphism in Caucasian women: a meta-analysis.
causal interaction
diagnostic usage
therapeutic application
unassigned
3
1
1
0
Breast Neoplasms
Myeloperoxidase polymorphism, menopausal status, and breast cancer risk: an update meta-analysis.
diagnostic usage
ongoing research
unassigned
1
1
0
Breast Neoplasms
Luminol-based bioluminescence imaging of mouse mammary tumors.
causal interaction
ongoing research
therapeutic application
unassigned
2
2
2
0
Breast Neoplasms
N-acetylglucosaminidase, myeloperoxidase and vascular endothelial growth factor serum levels in breast cancer patients.
diagnostic usage
ongoing research
unassigned
4
4
0
Breast Neoplasms
Inflammatory peroxidases promote breast cancer progression in mice via regulation of the tumour microenvironment.
unassigned
0
Breast Neoplasms
Creating a Biomarker Panel for Early Detection of Chemotherapy Related Cardiac Dysfunction in Breast Cancer Patients.
causal interaction
diagnostic usage
unassigned
1
1
0
Bronchial Diseases
Assessment of airway neutrophils by sputum colour: correlation with airways inflammation.
diagnostic usage
unassigned
1
0
Bronchial Hyperreactivity
Role of transient receptor potential vanilloid 1 receptors in endotoxin-induced airway inflammation in the mouse.
ongoing research
unassigned
2
0
Bronchial Hyperreactivity
Impaired defense mechanism against inflammation, hyperalgesia, and airway hyperreactivity in somatostatin 4 receptor gene-deleted mice.
causal interaction
therapeutic application
unassigned
4
1
0
Bronchiectasis
[Functional activity of the neutrophils in the bronchoalveolar space in chronic bronchitis and bronchiectasis]
causal interaction
diagnostic usage
unassigned
2
3
0
Bronchiectasis
Levels of neutrophil elastase and cathepsin B activities, and cystatins in human sputum: relationship to inflammation.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
1
3
1
Bronchiectasis
Bronchiectasis with myeloperoxidase antineutrophil cytoplasmic antibody and bactericidal/permeability-increasing protein antineutrophil cytoplasmic antibody.
ongoing research
unassigned
3
0
Bronchiectasis
Bronchial inflammation and colonization in patients with clinically stable bronchiectasis.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
2
1
0
Bronchiectasis
Neutrophils, myeloperoxidase, and bronchiectasis in cystic fibrosis: green is not good.
therapeutic application
unassigned
3
0
Bronchiectasis
Clinical phenotypes in adult patients with bronchiectasis.
diagnostic usage
therapeutic application
unassigned
3
1
0
Bronchiectasis
Blood Neutrophils Are Reprogrammed in Bronchiectasis.
ongoing research
therapeutic application
unassigned
1
1
0
Bronchiectasis
Myeloperoxidase oxidation of methionine associates with early cystic fibrosis lung disease.
therapeutic application
unassigned
3
0
Bronchiolitis
Bronchiolitis in adults. A reversible cause of airway obstruction associated with airway neutrophils and neutrophil products.
unassigned
0
Bronchiolitis
Eosinophil cationic protein in nasal secretion and in serum and myeloperoxidase in serum in respiratory syncytial virus bronchiolitis: relation to asthma and atopy.
causal interaction
diagnostic usage
ongoing research
therapeutic application
2
4
2
1
Bronchiolitis
Relationship between atopic status and nasal interleukin 10 and 11 levels in infants with respiratory syncytial virus bronchiolitis.
causal interaction
ongoing research
unassigned
4
3
0
Bronchitis
Inhaled corticosteroids in stable COPD patients: do they have effects on cells and molecular mediators of airway inflammation?
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
4
2
1
Bronchitis
Increased serum inflammatory markers as predictors of airway obstruction.
diagnostic usage
ongoing research
unassigned
3
4
0
Bronchitis
Development of a functional point-of-need diagnostic for myeloperoxidase detection to identify neutrophilic bronchitis.
diagnostic usage
therapeutic application
unassigned
3
1
0
Bronchitis, Chronic
[Functional activity of the neutrophils in the bronchoalveolar space in chronic bronchitis and bronchiectasis]
causal interaction
diagnostic usage
unassigned
2
3
0
Bronchitis, Chronic
Bronchial inflammation in chronic bronchitis assessed by measurement of cell products in bronchial lavage fluid.
causal interaction
diagnostic usage
unassigned
2
4
0
Bronchitis, Chronic
Effect of bacterial extract, IRS-19, on the concentration of hydrogen peroxide and myeloperoxidase activity in nasal washings of patients with chronic bronchitis.
ongoing research
therapeutic application
unassigned
2
2
0
Bronchitis, Chronic
[Effects of bacterial extract IRS-19 on the concentration of hydrogen peroxide and myeloperoxidase activity in nasal washings of patients with chronic bronchitis]
ongoing research
therapeutic application
unassigned
3
1
0
Bronchitis, Chronic
[A study on tumor necrosis factor alpha, macrophage inflammatory protein-2 and myeloperoxidase in blood, broncho-alveolar fluid and lung tissues of rat chronic bronchitis model]
diagnostic usage
ongoing research
unassigned
3
4
0
Bronchitis, Chronic
Sex differences in reported and objectively measured sleep in COPD.
causal interaction
unassigned
4
0
Bronchopneumonia
The involvement of polymorphonuclear leukocytes in the pathogenesis of bronchopneumonia in calves. IV. Myeloperoxidase activity.
causal interaction
unassigned
2
0
Bronchopneumonia
Bronchoalveolar lavage fluids of patients with lung injury activate the transcription factor nuclear factor-kappaB in an alveolar cell line.
ongoing research
unassigned
2
0
Bronchopneumonia
Bronchoalveolar lavage fluids of ventilated patients with acute lung injury activate NF-kappaB in alveolar epithelial cell line: role of reactive oxygen/nitrogen species and cytokines.
diagnostic usage
ongoing research
unassigned
2
3
0
Bronchopulmonary Dysplasia
Bronchoalveolar oxyradical inflammatory elements herald bronchopulmonary dysplasia.
unassigned
0
Bronchopulmonary Sequestration
Pulmonary damage by Vibrio vulnificus cytolysin.
causal interaction
therapeutic application
unassigned
4
1
0
Bronchopulmonary Sequestration
Prevention of ischemia-reperfusion lung injury by sulfated Lewis(a) pentasaccharide. The Paris-Sud University Lung Transplantation Group.
therapeutic application
unassigned
2
0
Bronchopulmonary Sequestration
The role of haem oxygenase-1 in the decrease of endothelial intercellular adhesion molecule-1 expression by curcumin.
causal interaction
therapeutic application
unassigned
1
1
0
Brucellosis
[The functional metabolic activity of the blood neutrophils in different clinical forms of brucellosis]
diagnostic usage
ongoing research
unassigned
4
4
0
Brucellosis
[Functional and metabolic activity of leukocytes in patients with chronic brucellosis]
causal interaction
diagnostic usage
ongoing research
therapeutic application
1
4
3
1
Brucellosis
Serum myeloperoxidase activity and oxidative stress in patients with acute brucellosis.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
4
4
1
Candidiasis
[The phagocytic activity of the neutrophilic granulocytes in patients with chronic candidiasis of the skin and mucous membranes]
unassigned
0
Candidiasis
[A spectrophotometric method of determining the myeloperoxidase activity in phagocytic cells]
causal interaction
diagnostic usage
unassigned
4
4
0
Candidiasis
Myeloperoxidase deficiency as a predisposing factor for deep mucocutaneous candidiasis: a case report.
causal interaction
unassigned
4
0
Candidiasis
Candidacidal activity of myeloperoxidase: therapeutic influence of the enzyme in vivo.
causal interaction
therapeutic application
unassigned
4
4
0
Candidiasis
Leukocyte myeloperoxidase deficiency and disseminated candidiasis: the role of myeloperoxidase in resistance to Candida infection.
causal interaction
unassigned
4
0
Candidiasis
Fungal infections in primary immunodeficiencies.
causal interaction
diagnostic usage
unassigned
4
1
0
Candidiasis, Invasive
Augmentation of human macrophage candidacidal capacity by recombinant human myeloperoxidase and granulocyte-macrophage colony-stimulating factor.
causal interaction
therapeutic application
unassigned
4
4
0
Candidiasis, Oral
Elevation of myeloperoxidase activity in infants with oral candidiasis treated with clotrimazole.
causal interaction
therapeutic application
unassigned
4
1
0
Candidiasis, Oral
Myeloperoxidase deficiency associated with atypical oral candidiasis: A clinical report.
causal interaction
unassigned
4
0
Candidiasis, Vulvovaginal
Propolis increases neutrophils response against Candida albicans through the increase of reactive oxygen species.
ongoing research
therapeutic application
unassigned
3
1
0
Carcinogenesis
Myeloperoxidase activity and whole blood chemiluminescence in bladder cancer--influence of smoking.
ongoing research
unassigned
2
0
Carcinogenesis
A myeloperoxidase polymorphism associated with reduced risk of lung cancer.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
3
1
0
Carcinogenesis
Association between asbestos exposure, cigarette smoking, myeloperoxidase (MPO) genotypes, and lung cancer risk.
causal interaction
diagnostic usage
unassigned
4
3
0
Carcinogenesis
Formation of acrolein-derived 2'-deoxyadenosine adduct in an iron-induced carcinogenesis model.
unassigned
0
Carcinogenesis
Myeloperoxidase -463G>A polymorphism and risk of primary lung cancer in a Korean population.
causal interaction
diagnostic usage
therapeutic application
unassigned
3
3
1
0
Carcinogenesis
Myeloperoxidase G-463A polymorphism and lung cancer: a HuGE genetic susceptibility to environmental carcinogens pooled analysis.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
3
1
0
Carcinogenesis
Cyclooxygenase-2 and Hypoxia-Inducible Factor-1alpha protein expression is related to inflammation, and up-regulated since the early steps of colorectal carcinogenesis.
causal interaction
diagnostic usage
ongoing research
unassigned
4
4
3
0
Carcinogenesis
Myeloperoxidase-induced genomic DNA-centered radicals.
causal interaction
therapeutic application
unassigned
2
1
0
Carcinogenesis
Benzene Metabolite, 1,2,4-Benzenetriol, Induces Halogenated DNA and Tyrosines Representing Halogenative Stress in Human Myeloid Cell Line HL-60.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
1
1
0
Carcinogenesis
The MPO-463G>A polymorphism and lung cancer risk: a meta-analysis based on 22 case-control studies.
causal interaction
therapeutic application
unassigned
4
1
0
Carcinogenesis
Role of the Vanins-Myeloperoxidase Axis in Colorectal Carcinogenesis.
causal interaction
unassigned
4
0
Carcinogenesis
Promutagenicity of 8-Chloroguanine, A Major Inflammation-Induced Halogenated DNA Lesion.
causal interaction
unassigned
3
0
Carcinoma
The activity of neutrophil myeloperoxidase in patients with lung carcinoma.
causal interaction
ongoing research
therapeutic application
unassigned
1
2
2
0
Carcinoma
Enzymatic deficiencies of the immune system cells in patients with cancer of the larynx and other malignancies.
causal interaction
diagnostic usage
ongoing research
unassigned
4
3
2
0
Carcinoma
Amplification units and translocation at chromosome 17q and c-erbB-2 overexpression in the pathogenesis of breast cancer.
unassigned
0
Carcinoma
Genetic polymorphism in myeloperoxidase but not GSTM1 is associated with risk of lung squamous cell carcinoma in a Chinese population.
causal interaction
diagnostic usage
ongoing research
therapeutic application
1
3
2
1
Carcinoma
Association of the polymorphisms of MTHFR C677T, VDR C352T, and MPO G463A with risk for esophageal squamous cell dysplasia and carcinoma.
causal interaction
diagnostic usage
ongoing research
therapeutic application
3
3
3
1
Carcinoma
Arsenic methylation capability, myeloperoxidase and sulfotransferase genetic polymorphisms, and the stage and grade of urothelial carcinoma.
causal interaction
diagnostic usage
unassigned
2
4
0
Carcinoma
Manganese superoxide dismutase and glutathione peroxidase as prognostic markers in patients with buccal mucosal squamous cell carcinomas.
causal interaction
diagnostic usage
ongoing research
unassigned
1
4
4
0
Carcinoma
Manganese superoxide dismutase and glutathione peroxidase as prognostic markers in patients with buccal mucosal squamous cell carcinomas.
causal interaction
diagnostic usage
ongoing research
unassigned
1
4
4
0
Carcinoma
Second primary tumors and myeloperoxidase expression in buccal mucosal squamous cell carcinoma.
diagnostic usage
ongoing research
unassigned
3
4
0
Carcinoma
Involvement of myeloperoxidase gene polymorphism 463G>A in development of cervical squamous cell carcinoma.
causal interaction
ongoing research
unassigned
3
2
0
Carcinoma
The association between immunoexpression levels of oxidant and antioxidant enzymes and lip squamous cell carcinoma.
causal interaction
diagnostic usage
ongoing research
unassigned
2
4
4
0
Carcinoma, Hepatocellular
Myeloperoxidase and superoxide dismutase 2 polymorphisms comodulate the risk of hepatocellular carcinoma and death in alcoholic cirrhosis.
causal interaction
diagnostic usage
unassigned
3
4
0
Carcinoma, Hepatocellular
A variant in myeloperoxidase promoter hastens the emergence of hepatocellular carcinoma in patients with HCV-related cirrhosis.
unassigned
0
Carcinoma, Hepatocellular
Plasma myeloperoxidase levels correlate with hepatocellular carcinoma in chronic hepatitis C.
causal interaction
diagnostic usage
unassigned
4
4
0
Carcinoma, Intraductal, Noninfiltrating
Amplification units and translocation at chromosome 17q and c-erbB-2 overexpression in the pathogenesis of breast cancer.
unassigned
0
Carcinoma, Non-Small-Cell Lung
Polymorphisms of the GSTM1, GSTP1, MPO, XRCC1, and NQO1 genes in Chinese patients with non-small cell lung cancers: relationship with aberrant promoter methylation of the CDKN2A and RARB genes.
causal interaction
diagnostic usage
ongoing research
unassigned
1
2
1
0
Carcinoma, Ovarian Epithelial
Myeloperoxidase serves as a redox switch that regulates apoptosis in epithelial ovarian cancer.
causal interaction
diagnostic usage
ongoing research
therapeutic application
1
3
4
3
Carcinoma, Squamous Cell
Genetic polymorphism in myeloperoxidase but not GSTM1 is associated with risk of lung squamous cell carcinoma in a Chinese population.
causal interaction
diagnostic usage
ongoing research
therapeutic application
1
3
2
1
Carcinoma, Squamous Cell
Manganese superoxide dismutase and glutathione peroxidase as prognostic markers in patients with buccal mucosal squamous cell carcinomas.
causal interaction
diagnostic usage
ongoing research
unassigned
1
4
4
0
Carcinoma, Squamous Cell
Manganese superoxide dismutase and glutathione peroxidase as prognostic markers in patients with buccal mucosal squamous cell carcinomas.
causal interaction
diagnostic usage
ongoing research
unassigned
1
4
4
0
Carcinoma, Squamous Cell
Second primary tumors and myeloperoxidase expression in buccal mucosal squamous cell carcinoma.
diagnostic usage
ongoing research
unassigned
3
4
0
Carcinoma, Squamous Cell
Involvement of myeloperoxidase gene polymorphism 463G>A in development of cervical squamous cell carcinoma.
causal interaction
ongoing research
unassigned
3
2
0
Carcinoma, Squamous Cell
The association between immunoexpression levels of oxidant and antioxidant enzymes and lip squamous cell carcinoma.
causal interaction
diagnostic usage
ongoing research
unassigned
2
4
4
0
Carcinosarcoma
The influence of lactoferrin on elemental homeostasis and activity of metal-containing enzymes in rats with Walker-256 carcinosarcoma.
ongoing research
therapeutic application
unassigned
2
1
0
Cardiomyopathies
Activation of polymorphonuclear neutrophils in patients with impaired left ventricular function.
causal interaction
diagnostic usage
therapeutic application
unassigned
3
1
1
0
Cardiotoxicity
The protective effect of a purified extract of Withania somnifera against doxorubicin-induced cardiac toxicity in rats.
causal interaction
ongoing research
unassigned
2
1
0
Cardiotoxicity
Melatonin protects against ischemic heart failure in rats.
unassigned
0
Cardiotoxicity
Longitudinal Changes in Multiple Biomarkers Are Associated with Cardiotoxicity in Breast Cancer Patients Treated with Doxorubicin, Taxanes, and Trastuzumab.
unassigned
0
Cardiotoxicity
Anthracycline induced cardiotoxicity: biomarkers and "Omics" technology in the era of patient specific care.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
1
3
0
Cardiotoxicity
Creating a Biomarker Panel for Early Detection of Chemotherapy Related Cardiac Dysfunction in Breast Cancer Patients.
causal interaction
diagnostic usage
unassigned
1
1
0
Cardiotoxicity
Update on Incorporating Biomarkers with Imaging Findings for the Detection and Management of Cardiotoxicity.
causal interaction
unassigned
4
0
Cardiotoxicity
The role of cardiac biomarkers in cardio-oncology.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
1
4
0
Cardiotoxicity
Pilot study of bevacizumab in combination with docetaxel and cyclophosphamide as adjuvant treatment for patients with early stage HER-2 negative breast cancer, including analysis of candidate circulating markers of cardiac toxicity: ICORG 08-10 trial.
causal interaction
diagnostic usage
ongoing research
therapeutic application
2
4
1
4
Cardiovascular Diseases
Oxidized amino acids: culprits in human atherosclerosis and indicators of oxidative stress.
causal interaction
unassigned
1
0
Cardiovascular Diseases
A functional variant of the myeloperoxidase gene is associated with cardiovascular disease in end-stage renal disease patients.
unassigned
0
Cardiovascular Diseases
Emerging role of myeloperoxidase and oxidant stress markers in cardiovascular risk assessment.
causal interaction
therapeutic application
unassigned
4
1
0
Cardiovascular Diseases
Prognostic value of myeloperoxidase in patients with chest pain.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
4
2
0
Cardiovascular Diseases
Inflammatory and oxidative markers in atherosclerosis: relationship to outcome.
causal interaction
diagnostic usage
therapeutic application
unassigned
3
4
1
0
Cardiovascular Diseases
Serum myeloperoxidase levels independently predict endothelial dysfunction in humans.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
2
2
0
Cardiovascular Diseases
A novel multistep mechanism for oxygen binding to ferrous hemoproteins: rapid kinetic analysis of ferrous-dioxy myeloperoxidase (compound III) formation.
causal interaction
unassigned
3
0
Cardiovascular Diseases
Localization of nitration and chlorination sites on apolipoprotein A-I catalyzed by myeloperoxidase in human atheroma and associated oxidative impairment in ABCA1-dependent cholesterol efflux from macrophages.
causal interaction
unassigned
4
0
Cardiovascular Diseases
Myeloperoxidase and cardiovascular disease.
diagnostic usage
ongoing research
unassigned
4
4
0
Cardiovascular Diseases
Myeloperoxidase genetic polymorphisms modulate human neutrophil enzyme activity: genetic determinants for atherosclerosis?
causal interaction
therapeutic application
unassigned
1
1
0
Cardiovascular Diseases
Pathways for oxidation of high-density lipoprotein in human cardiovascular disease.
causal interaction
diagnostic usage
unassigned
1
1
0
Cardiovascular Diseases
Myeloperoxidase and C-reactive protein augment the specificity of B-type natriuretic peptide in community screening for systolic heart failure.
causal interaction
diagnostic usage
therapeutic application
unassigned
2
2
1
0
Cardiovascular Diseases
Statin treatment and diabetes affect myeloperoxidase activity in maintenance hemodialysis patients.
causal interaction
unassigned
4
0
Cardiovascular Diseases
Activation of polymorphonuclear neutrophils in patients with impaired left ventricular function.
causal interaction
diagnostic usage
therapeutic application
unassigned
3
1
1
0
Cardiovascular Diseases
Myeloperoxidase and inflammatory proteins: pathways for generating dysfunctional high-density lipoprotein in humans.
causal interaction
therapeutic application
unassigned
2
3
0
Cardiovascular Diseases
Effect of collection tube type and preanalytical handling on myeloperoxidase concentrations.
causal interaction
therapeutic application
unassigned
4
4
0
Cardiovascular Diseases
Flavonoids as substrates and inhibitors of myeloperoxidase: molecular actions of aglycone and metabolites.
causal interaction
unassigned
2
0
Cardiovascular Diseases
Nanomonitors: electrical immunoassays for protein biomarker profiling.
diagnostic usage
therapeutic application
unassigned
4
1
0
Cardiovascular Diseases
Methionine oxidation impairs reverse cholesterol transport by apolipoprotein A-I.
unassigned
0
Cardiovascular Diseases
Novel biomarkers of cardiovascular disease: myeloperoxidase for acute and/or chronic heart failure?
causal interaction
ongoing research
therapeutic application
unassigned
3
1
2
0
Cardiovascular Diseases
Myeloperoxidase and paraoxonase-1 in type 2 diabetic patients.
causal interaction
ongoing research
therapeutic application
unassigned
4
3
2
0
Cardiovascular Diseases
Iridium oxide nanomonitors: Clinical diagnostic devices for health monitoring systems.
diagnostic usage
therapeutic application
unassigned
2
1
0
Cardiovascular Diseases
Determination of myeloperoxidase in EDTA plasma: comparison of an enzyme-linked immunosorbent assay with a chemiluminescent automated immunoassay.
diagnostic usage
unassigned
2
0
Cardiovascular Diseases
Myeloperoxidase: a useful biomarker for cardiovascular disease risk stratification?
diagnostic usage
therapeutic application
unassigned
4
3
0
Cardiovascular Diseases
Myeloperoxidase, subclinical atherosclerosis, and cardiovascular disease events.
diagnostic usage
ongoing research
therapeutic application
unassigned
4
4
3
0
Cardiovascular Diseases
No relationship between neutrophil granulocyte activation and the myeloperoxidase gene - 129 G>A and - 463 G>A promoter polymorphisms: implications for investigations of cardiovascular disease.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
4
1
0
Cardiovascular Diseases
Hyperglycemia and Oxidative Stress Strengthen the Association Between Myeloperoxidase and Blood Pressure.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
1
2
4
Cardiovascular Diseases
Oenothera paradoxa defatted seeds extract and its bioactive component penta-O-galloyl-?-D-glucose decreased production of reactive oxygen species and inhibited release of leukotriene B4, interleukin-8, elastase, and myeloperoxidase in human neutrophils.
causal interaction
therapeutic application
unassigned
2
2
0
Cardiovascular Diseases
Diagnostic value of MPO plasma levels in patients admitted for suspected myocardial infarction.
causal interaction
diagnostic usage
unassigned
4
1
0
Cardiovascular Diseases
Effect of blood sample type on the measurement of advanced oxidation protein products as a biomarker of inflammation and oxidative stress in hemodialysis patients.
unassigned
0
Cardiovascular Diseases
Leukocyte counts, myeloperoxidase, and pregnancy-associated plasma protein a as biomarkers for cardiovascular disease: towards a multi-biomarker approach.
causal interaction
diagnostic usage
ongoing research
therapeutic application
3
3
3
2
Cardiovascular Diseases
Urate as a Physiological Substrate for Myeloperoxidase: IMPLICATIONS FOR HYPERURICEMIA AND INFLAMMATION.
causal interaction
unassigned
4
0
Cardiovascular Diseases
Lipid oxidation by hypochlorous acid: chlorinated lipids in atherosclerosis and myocardial ischemia.
causal interaction
unassigned
2
0
Cardiovascular Diseases
Myeloperoxidase modulation by LDL apheresis in familial hypercholesterolemia.
causal interaction
therapeutic application
unassigned
4
1
0
Cardiovascular Diseases
Pathogenic cycle between the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine and the leukocyte-derived hemoprotein myeloperoxidase.
causal interaction
therapeutic application
unassigned
1
1
0
Cardiovascular Diseases
Myeloperoxidase in chronic kidney disease.
causal interaction
diagnostic usage
ongoing research
unassigned
4
3
2
0
Cardiovascular Diseases
Myeloperoxidase in the plasma and placenta of normal pregnant women and women with pregnancies complicated by preeclampsia and intrauterine growth restriction.
causal interaction
diagnostic usage
ongoing research
unassigned
4
3
2
0
Cardiovascular Diseases
Developing and assessing cardiovascular biomarkers.
diagnostic usage
therapeutic application
unassigned
3
4
0
Cardiovascular Diseases
Fibrosis in Atrial Fibrillation - Role of Reactive Species and MPO.
causal interaction
unassigned
3
0
Cardiovascular Diseases
Myeloperoxidase - a leukocyte-derived protagonist of inflammation and cardiovascular disease.
unassigned
0
Cardiovascular Diseases
Myeloperoxidase Is an Early Biomarker of Inflammation and Cardiovascular Risk in Prepubertal Obese Children.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
2
1
0
Cardiovascular Diseases
High-density lipoprotein nitration and chlorination catalyzed by myeloperoxidase impair its effect of promoting endothelial repair.
unassigned
0
Cardiovascular Diseases
Myeloperoxidase: expressing inflammation and oxidative stress in cardiovascular disease.
causal interaction
ongoing research
unassigned
2
1
0
Cardiovascular Diseases
The relation of serum myeloperoxidase to disease progression and mortality in patients with chronic obstructive pulmonary disease (COPD).
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
4
2
1
Cardiovascular Diseases
Myeloperoxidase in cardiovascular disease.
causal interaction
ongoing research
unassigned
1
1
0
Cardiovascular Diseases
Alpha-chlorofatty Acid and coronary artery or aorta calcium scores in women with systemic lupus erythematosus. A pilot study.
causal interaction
therapeutic application
unassigned
1
1
0
Cardiovascular Diseases
B-Type natriuretic peptide suppression of neutrophil superoxide generation: mechanistic studies in normal subjects.
causal interaction
therapeutic application
unassigned
3
1
0
Cardiovascular Diseases
Myeloperoxidase-mediated oxidation targets serum apolipoprotein A-I in diabetic patients and represents a potential mechanism leading to impaired anti-apoptotic activity of high density lipoprotein.
diagnostic usage
therapeutic application
unassigned
1
1
0
Cardiovascular Diseases
A rapid bioluminescence assay for measuring myeloperoxidase activity in human plasma.
causal interaction
diagnostic usage
unassigned
3
4
0
Cardiovascular Diseases
Myeloperoxidase evokes substantial vasomotor responses in isolated skeletal muscle arterioles of the rat.
therapeutic application
unassigned
1
0
Cardiovascular Diseases
Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular Diseases.
causal interaction
therapeutic application
unassigned
1
4
0
Cardiovascular Diseases
Pharmacokinetics and Disposition of the Thiouracil Derivative PF-06282999, an Orally Bioavailable, Irreversible Inactivator of Myeloperoxidase Enzyme, Across Animals and Humans.
causal interaction
therapeutic application
unassigned
3
4
0
Cardiovascular Diseases
Neutrophil myeloperoxidase and its substrates: formation of specific markers and reactive compounds during inflammation.
unassigned
0
Cardiovascular Diseases
Assessment of oxidative stress and inflammation in prediabetes-A hospital based cross-sectional study.
diagnostic usage
ongoing research
unassigned
1
2
0
Cardiovascular Diseases
Roles of myeloperoxidase and GAPDH in interferon-gamma production of GM-CSF-dependent macrophages.
causal interaction
unassigned
2
0
Cardiovascular Diseases
Myeloperoxidase, asymmetric dimethyl-arginine and the renin-angiotensin-aldosterone-system in cardiovascular risk patients: Cross-sectional findings from the Ludwigshafen Risk and Cardiovascular Health (LURIC) study.
causal interaction
unassigned
2
0
Cardiovascular Diseases
Matrix metalloproteinase-8 and tissue inhibitor of matrix metalloproteinase-1 predict incident cardiovascular disease events and all-cause mortality in a population-based cohort.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
3
4
3
Cardiovascular Diseases
Mesna (2-mercaptoethane sodium sulfonate) functions as a regulator of myeloperoxidase.
causal interaction
unassigned
4
0
Cardiovascular Diseases
Induction of human cytochrome P450 3A4 by the irreversible myeloperoxidase inactivator PF-06282999 is mediated by the pregnane X receptor.
causal interaction
therapeutic application
unassigned
1
2
0
Cardiovascular Diseases
Role of Salivary Biomarkers in Detection of Cardiovascular Diseases (CVD).
causal interaction
therapeutic application
unassigned
2
2
0
Cardiovascular Diseases
Levels of Nitric Oxide Metabolites and Myeloperoxidase in Subjects with Type 2 Diabetes Mellitus on Metformin Therapy?.
causal interaction
diagnostic usage
ongoing research
unassigned
3
4
4
0
Cardiovascular Diseases
A myeloperoxidase precursor, pro-myeloperoxidase, is present in human plasma and elevated in cardiovascular disease patients.
causal interaction
diagnostic usage
ongoing research
therapeutic application
3
3
2
2
Cardiovascular Diseases
Neutrophil elastase and myeloperoxidase mRNA expression in overweight and obese subjects.
causal interaction
diagnostic usage
unassigned
4
3
0
Cardiovascular Diseases
Discovery of 1-((6-Aminopyridin-3-yl)Methyl)-3-(4-Bromophenyl)Urea as a Potent, Irreversible Myeloperoxidase Inhibitor.
causal interaction
therapeutic application
unassigned
4
1
0
Cardiovascular Diseases
Cross-sectional correlates of myeloperoxidase and alpha-1-acid glycoprotein with adiposity, atherogenic and hematological indices in metabolic syndrome patients with or without diabetes.
causal interaction
ongoing research
unassigned
2
1
0
Cardiovascular Diseases
Therapeutic Lifestyle Changes Improve HDL Function by Inhibiting Myeloperoxidase-Mediated Oxidation in Patients With Metabolic Syndrome.
causal interaction
unassigned
3
0
Cardiovascular Diseases
Association of monocyte myeloperoxidase with incident cardiovascular disease: The Atherosclerosis Risk in Communities Study.
causal interaction
ongoing research
unassigned
3
2
0
Cardiovascular Diseases
Alterations of HDL Particles in Children with End-stage Renal Disease.
causal interaction
diagnostic usage
unassigned
4
1
0
Cardiovascular Diseases
Safety, tolerability, pharmacokinetics and effect on serum uric acid of the myeloperoxidase inhibitor AZD4831 in a randomized, placebo-controlled, phase I study in healthy volunteers.
causal interaction
unassigned
1
0
Cardiovascular Diseases
Association of myeloperoxidase with cardiovascular disease risk factors in prediabetic subjects.
causal interaction
unassigned
4
0
Cardiovascular Diseases
Effects of selenium supplementation on paraoxonase-1 and myeloperoxidase activity in subjects with cardiovascular disease: the Selenegene study, a double-blind randomized controlled trial.
ongoing research
unassigned
4
0
Cardiovascular Diseases
Myeloperoxidase - A bridge linking inflammation and oxidative stress with cardiovascular disease.
causal interaction
unassigned
2
0
Cardiovascular Diseases
Inhibiting myeloperoxidase prevents onset and reverses established high-fat diet-induced microvascular insulin resistance.
causal interaction
therapeutic application
unassigned
4
3
0
Cardiovascular Diseases
Myeloperoxidase and the Risk of CKD Progression, Cardiovascular Disease, and Death in the Chronic Renal Insufficiency Cohort (CRIC) Study.
causal interaction
diagnostic usage
unassigned
4
2
0
Cardiovascular Diseases
Can high-intensity interval training improve physical and mental health outcomes? A meta-review of 33 systematic reviews across the lifespan.
therapeutic application
unassigned
1
0
Cardiovascular Diseases
Linking myeloperoxidase with subclinical atherosclerosis in adults with metabolic syndrome.
causal interaction
diagnostic usage
ongoing research
therapeutic application
3
4
3
2
Carotid Artery Diseases
Myeloperoxidase predicts progression of carotid stenosis in states of low high-density lipoprotein cholesterol.
causal interaction
diagnostic usage
ongoing research
unassigned
4
3
2
0
Carotid Artery Diseases
Myeloperoxidase levels are not associated with carotid atherosclerosis progression in patients with familial hypercholesterolemia.
causal interaction
unassigned
3
0
Carotid Artery Diseases
The association of myeloperoxidase promoter polymorphism with carotid atherosclerosis is abolished in patients with type 2 diabetes.
causal interaction
ongoing research
therapeutic application
unassigned
1
3
1
0
Carotid Artery Diseases
Association of myeloperoxidase gene variation with carotid atherosclerosis in patients with essential hypertension.
causal interaction
ongoing research
unassigned
3
4
0
Carotid Stenosis
Myeloperoxidase predicts progression of carotid stenosis in states of low high-density lipoprotein cholesterol.
causal interaction
diagnostic usage
ongoing research
unassigned
4
3
2
0
catalase deficiency
Catalase deficiency in myeloperoxidase deficient polymorphonuclear leucocytes from chicken.
diagnostic usage
ongoing research
therapeutic application
unassigned
2
1
1
0
Catalepsy
Gastrodin microinjection suppresses 6-OHDA-induced motor impairments in parkinsonian rats: insights into oxidative balance and microglial activation in SNc.
causal interaction
ongoing research
unassigned
2
4
0
Cataract
[Characteristics of chloramine complexes of carnosine with hypochlorite anion]
ongoing research
unassigned
1
0
Cataract
[The role of myeloperoxidase, a product of the polymorphonuclear leukocytes, in the pathogenesis of cataract]
causal interaction
diagnostic usage
therapeutic application
unassigned
4
2
1
0
Cerebral Hemorrhage
Serum myeloperoxidase concentrations for outcome prediction in acute intracerebral hemorrhage.
causal interaction
diagnostic usage
unassigned
1
4
0
Cerebral Hemorrhage
Resveratrol ameliorates brain injury via the TGF-?-mediated ERK signaling pathway in a rat model of cerebral hemorrhage.
causal interaction
ongoing research
unassigned
1
2
0
Cerebral Infarction
17beta-estradiol potentiates ischemia-reperfusion injury in diabetic ovariectomized female rats.
diagnostic usage
ongoing research
unassigned
3
3
0
Cerebral Infarction
Neuroprotective Effect of Baicalin in a Rat Model of Permanent Focal Cerebral Ischemia.
diagnostic usage
unassigned
3
0
Cerebral Infarction
The anti-inflammatory effect of paeoniflorin on cerebral infarction induced by ischemia-reperfusion injury in Sprague-Dawley rats.
ongoing research
unassigned
2
0
Cerebral Infarction
Protective effects of allicin against ischemic stroke in a rat model of middle cerebral artery occlusion.
diagnostic usage
unassigned
3
0
Cerebral Infarction
Resveratrol alleviates nerve injury after cerebral ischemia and reperfusion in mice by inhibiting inflammation and apoptosis.
causal interaction
therapeutic application
unassigned
3
3
0
Cerebral Infarction
Pre-Treatment with Metformin in Comparison with Post-Treatment Reduces Cerebral Ischemia Reperfusion Induced Injuries in Rats.
diagnostic usage
therapeutic application
unassigned
4
1
0
Cerebral Infarction
Resveratrol downregulates the TLR4 signaling pathway to reduce brain damage in a rat model of focal cerebral ischemia.
diagnostic usage
ongoing research
therapeutic application
unassigned
4
2
1
0
Cerebral Palsy
Association of cord blood cytokines with prematurity and cerebral palsy.
diagnostic usage
ongoing research
unassigned
2
4
0
Cerebral Small Vessel Diseases
Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
4
2
0
Cerebrovascular Disorders
New biochemical markers in acute coronary syndromes.
causal interaction
diagnostic usage
unassigned
4
1
0
Cerebrovascular Disorders
Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
4
2
0
Cerebrovascular Disorders
High-resolution Imaging of Myeloperoxidase Activity Sensors in Human Cerebrovascular Disease.
diagnostic usage
ongoing research
therapeutic application
unassigned
1
3
1
0
Chagas Disease
Inactivation of Trypanosoma cruzi dihydrolipoamide dehydrogenase by leukocyte myeloperoxidase systems: role of hypochloride and nitrite related radicals.
therapeutic application
unassigned
4
0
Chagas Disease
Enhanced nitrosative stress during Trypanosoma cruzi infection causes nitrotyrosine modification of host proteins: implications in Chagas' disease.
causal interaction
unassigned
2
0
Chagas Disease
Increased myeloperoxidase activity and protein nitration are indicators of inflammation in patients with Chagas' disease.
causal interaction
unassigned
4
0
Chediak-Higashi Syndrome
Defective polymorphonuclear leukocyte metabolism and function in canine cyclic neutropenia.
causal interaction
diagnostic usage
unassigned
4
1
0
Chediak-Higashi Syndrome
Biochemical studies on the leukocytes in Chediak-Higashi syndrome.
causal interaction
ongoing research
therapeutic application
unassigned
2
3
1
0
Chediak-Higashi Syndrome
Normal-sized primary lysosomes are present in Chediak-Higashi syndrome neutrophils.
diagnostic usage
ongoing research
therapeutic application
unassigned
2
4
1
0
Chediak-Higashi Syndrome
Phagocyte defects.
causal interaction
diagnostic usage
unassigned
4
1
0
Chediak-Higashi Syndrome
Neutrophil function studies in clinical medicine.
causal interaction
diagnostic usage
unassigned
4
3
0
Chediak-Higashi Syndrome
Congenital disorders of the function of polymorphonuclear neutrophils.
causal interaction
therapeutic application
unassigned
4
1
0
Chediak-Higashi Syndrome
[Hereditary polymorphonuclear neutrophil deficiencies]
causal interaction
diagnostic usage
unassigned
4
1
0
Cheilitis
Noma-like gangrenous cheilitis in a child with cyclic neutropenia associated with myeloperoxidase deficiency.
causal interaction
unassigned
4
0
Cholangitis, Sclerosing
Anti-lactoferrin antibodies and other types of ANCA in ulcerative colitis, primary sclerosing cholangitis, and Crohn's disease.
causal interaction
diagnostic usage
ongoing research
unassigned
2
4
4
0
Cholangitis, Sclerosing
Simultaneous automated screening and confirmatory testing for vasculitis-specific ANCA.
diagnostic usage
therapeutic application
unassigned
1
1
0
Cholecystitis
The effect of capsaicin on gallbladder fluid absorption.
diagnostic usage
ongoing research
unassigned
4
4
0
Cholecystitis
The role of prostanoids in the production of acute acalculous cholecystitis by platelet-activating factor.
diagnostic usage
ongoing research
unassigned
3
4
0
Cholecystitis
The production of experimental cholecystitis by endotoxin.
diagnostic usage
ongoing research
unassigned
3
2
0
Cholecystitis
Interleukin-1 mediates guinea pig gallbladder inflammation in vivo.
unassigned
0
Cholecystitis, Acute
[Functional-metabolic activity of leukocytes in patients with cholecystitis]
diagnostic usage
ongoing research
therapeutic application
unassigned
3
3
1
0
Cholera
Neuronal involvement in the intestinal effects of Clostridium difficile toxin A and Vibrio cholerae enterotoxin in rat ileum.
ongoing research
therapeutic application
unassigned
4
4
0
Cholestasis
Protective Effect of Brazilian Propolis against Liver Damage with Cholestasis in Rats Treated with ?-Naphthylisothiocyanate.
unassigned
0
Cholesteatoma
Is there a relationship between myeloperoxidase activity and conductive hearing loss in chronic otitis media complicated by cholesteatoma?
causal interaction
diagnostic usage
ongoing research
unassigned
3
4
4
0
Chorioamnionitis
Persistence after birth of systemic inflammation associated with umbilical cord inflammation.
unassigned
0
Chorioamnionitis
Amniotic fluid myeloperoxidase in pregnancies complicated by preterm prelabor rupture of membranes.
unassigned
0
Chorioamnionitis
Surfactant Components and Tracheal Aspirate Inflammatory Markers in Preterm Infants with Respiratory Distress Syndrome.
causal interaction
unassigned
2
0
Chronic Periodontitis
Myeloperoxidase activity in peripheral blood, neutrophil crevicular fluid and whole saliva of patients with periodontal disease.
diagnostic usage
ongoing research
therapeutic application
unassigned
4
3
1
0
Chronic Periodontitis
The importance of data presentation regarding gingival crevicular fluid myeloperoxidase and elastase-like activity in periodontal disease and health status.
diagnostic usage
ongoing research
unassigned
3
4
0
Chronic Periodontitis
Amplified crevicular leukocyte activity in aggressive periodontal disease.
causal interaction
diagnostic usage
ongoing research
therapeutic application
1
2
1
1
Chronic Periodontitis
Gingival crevicular fluid levels of MMP-8, MMP-9, TIMP-2, and MPO decrease after periodontal therapy.
causal interaction
ongoing research
unassigned
1
3
0
Chronic Periodontitis
Smoking and matrix metalloproteinases, neutrophil elastase and myeloperoxidase in chronic periodontitis.
causal interaction
ongoing research
unassigned
4
4
0
Chronic Periodontitis
Associations between matrix metalloproteinase-8 and -14 and myeloperoxidase in gingival crevicular fluid from subjects with progressive chronic periodontitis: a longitudinal study.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
4
3
3
Chronic Periodontitis
Evaluation of Systemic Levels of Neutrophilic Enzymes in Hypertensive Patients With Chronic Periodontitis.
diagnostic usage
ongoing research
unassigned
4
4
0
Chronic Periodontitis
Matrix metalloproteinases and myeloperoxidase in gingival crevicular fluid provide site-specific diagnostic value for chronic periodontitis.
diagnostic usage
ongoing research
unassigned
3
2
0
Chronic Periodontitis
Serum and salivary matrix metalloproteinases, neutrophil elastase, myeloperoxidase in patients with chronic or aggressive periodontitis.
causal interaction
ongoing research
unassigned
1
4
0
Chronic Periodontitis
Aggressive periodontitis: An appraisal of systemic effects on its etiology-genetic aspect.
causal interaction
diagnostic usage
ongoing research
therapeutic application
4
1
4
1
Chronic Urticaria
Skin and Systemic Inflammation in Schnitzler's Syndrome Are Associated With Neutrophil Extracellular Trap Formation.
diagnostic usage
ongoing research
unassigned
2
3
0
Churg-Strauss Syndrome
[Antineutrophil cytoplasmic antibodies--ANCA]
therapeutic application
unassigned
2
0
Churg-Strauss Syndrome
Antineutrophil cytoplasmic antibodies: a still-growing class of autoantibodies in inflammatory disorders.
causal interaction
diagnostic usage
therapeutic application
unassigned
4
1
1
0
Churg-Strauss Syndrome
Detection of autoantibodies against myeloid lysosomal enzymes: a useful adjunct to classification of patients with biopsy-proven necrotizing arteritis.
causal interaction
diagnostic usage
ongoing research
therapeutic application
1
4
2
1
Churg-Strauss Syndrome
[Autoantibodies associated with vasculitis]
causal interaction
unassigned
1
0
Churg-Strauss Syndrome
Correlation of antineutrophil cytoplasmic antibodies with the extrarenal histopathology of Wegener's (pathergic) granulomatosis and related forms of vasculitis.
diagnostic usage
therapeutic application
unassigned
2
1
0
Churg-Strauss Syndrome
[Clinical study on five myeloperoxidase specific anti-neutrophil cytoplasmic antibody (MPO-ANCA) positive Churg-Strauss syndrome cases]
diagnostic usage
ongoing research
therapeutic application
unassigned
2
4
2
0
Churg-Strauss Syndrome
What is new with anti-neutrophil cytoplasmic antibodies: diagnostic, pathogenetic and therapeutic implications.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
3
1
0
Churg-Strauss Syndrome
[Microscopic polyangiitis]
causal interaction
diagnostic usage
therapeutic application
unassigned
1
1
3
0
Churg-Strauss Syndrome
Distinct differences in autoantigen specificity of anti-neutrophil cytoplasm antibodies in systemic vasculitides and other inflammatory diseases.
diagnostic usage
therapeutic application
unassigned
2
1
0
Churg-Strauss Syndrome
Prevalence of antineutrophil cytoplasmic antibodies in patients with various pulmonary diseases or multiorgan dysfunction.
diagnostic usage
therapeutic application
unassigned
2
2
0
Churg-Strauss Syndrome
Autoantibodies in vasculitis.
causal interaction
diagnostic usage
unassigned
1
3
0
Churg-Strauss Syndrome
New insights into the pathogenesis of antineutrophil cytoplasmic autoantibody-associated vasculitis.
unassigned
0
Churg-Strauss Syndrome
Aggravation of anti-myeloperoxidase antibody-induced glomerulonephritis by bacterial lipopolysaccharide: role of tumor necrosis factor-alpha.
causal interaction
unassigned
1
0
Churg-Strauss Syndrome
Antineutrophil cytoplasmic autoantibody-associated small-vessel vasculitis.
diagnostic usage
unassigned
1
0
Churg-Strauss Syndrome
[Classification of systemic vasculatides]
causal interaction
therapeutic application
unassigned
1
1
0
Churg-Strauss Syndrome
Meta-analysis of myeloperoxidase G-463/A polymorphism in anti-neutrophil cytoplasmic autoantibody-positive vasculitis.
causal interaction
diagnostic usage
therapeutic application
unassigned
1
3
1
0
Churg-Strauss Syndrome
Antibodies to selected minor target antigens in patients with anti-neutrophil cytoplasmic antibodies (ANCA).
causal interaction
diagnostic usage
therapeutic application
unassigned
1
3
1
0
Churg-Strauss Syndrome
TNF-alpha bioactivity-inhibiting therapy in ANCA-associated vasculitis: clinical and experimental considerations.
diagnostic usage
unassigned
1
0
Churg-Strauss Syndrome
Pathogenesis of PR3-ANCA associated vasculitis.
causal interaction
unassigned
1
0
Churg-Strauss Syndrome
Pathways to ANCA production: from differentiation of dendritic cells by proteinase 3 to B lymphocyte maturation in Wegener's granuloma.
diagnostic usage
ongoing research
therapeutic application
unassigned
1
2
1
0
Churg-Strauss Syndrome
Determination of anti-neutrophil cytoplasmic antibodies in small vessel vasculitis: Comparative analysis of different strategies.
causal interaction
diagnostic usage
unassigned
3
1
0
Churg-Strauss Syndrome
A comparative study of the diagnostic accuracy of ELISA systems for the detection of anti-neutrophil cytoplasm antibodies available in Japan and Europe.
diagnostic usage
ongoing research
unassigned
4
3
0
Churg-Strauss Syndrome
Pathophysiology of ANCA-associated small vessel vasculitis.
diagnostic usage
unassigned
1
0
Churg-Strauss Syndrome
Re-evaluation of 129 patients with systemic necrotizing vasculitides by using classification algorithm according to consensus methodology.
diagnostic usage
ongoing research
therapeutic application
unassigned
2
1
1
0
Churg-Strauss Syndrome
Churg-strauss syndrome presenting with acute renal insufficiency accompanied by eosinophilic tubulointerstitial nephritis.
unassigned
0
Coinfection
Enteroaggregative E. coli Subclinical Infection and co-Infections and Impaired Child Growth in the MAL-ED Cohort Study.
unassigned
0
Coinfection
Enteroaggregative Escherichia coli Subclinical Infection and Coinfections and Impaired Child Growth in the MAL-ED Cohort Study.
unassigned
0
Coinfection
Neutrophil Dysfunction in the Airways of Children with Acute Respiratory Failure Due to Lower Respiratory Tract Viral and Bacterial Coinfections.
unassigned
0
Colic
Assessment of systemic inflammation by time-trends of blood granulocyte count and plasma myeloperoxidase and elastase concentrations following colic surgery in horses.
diagnostic usage
ongoing research
therapeutic application
unassigned
4
3
1
0
Colitis
Exacerbation of experimental colitis by nonsteroidal anti-inflammatory drugs is not related to elevated leukotriene B4 synthesis.
causal interaction
ongoing research
therapeutic application
unassigned
2
4
4
0
Colitis
Verapamil alters eicosanoid synthesis and accelerates healing during experimental colitis in rats.
ongoing research
unassigned
3
0
Colitis
Prevention and reversal of experimental colitis by a monoclonal antibody which inhibits leukocyte adherence.
diagnostic usage
therapeutic application
unassigned
4
3
0
Colitis
Indomethacin worsens and a leukotriene biosynthesis inhibitor accelerates mucosal healing in rat colitis.
ongoing research
unassigned
3
0
Colitis
Mucosal protective activity of prostaglandin analogs in rodent colonic inflammation.
diagnostic usage
unassigned
4
0
Colitis
Granulocyte infiltration in experimental colitis in the rat is interleukin-1 dependent and leukotriene independent.
causal interaction
unassigned
4
0
Colitis
Inflammatory mediators in cotton-top tamarins (CTT) with acute and chronic colitis.
causal interaction
unassigned
3
0
Colitis
Clinical relevance of oxygen radicals in inflammatory bowel disease--facts and fashion.
causal interaction
therapeutic application
unassigned
4
4
0
Colitis
Evaluation of an interleukin-1 receptor antagonist in the rat acetic acid-induced colitis model.
therapeutic application
unassigned
1
0
Colitis
An orally active inhibitor of leukotriene synthesis accelerates healing in a rat model of colitis.
therapeutic application
unassigned
3
0
Colitis
Colonic inflammation in the rabbit induced by phorbol-12-myristate-13-acetate.
diagnostic usage
unassigned
3
0
Colitis
Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease.
causal interaction
therapeutic application
unassigned
2
4
0
Colitis
Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models.
causal interaction
ongoing research
unassigned
2
2
0
Colitis
A glucocorticoid prodrug facilitates normal mucosal function in rat colitis without adrenal suppression.
diagnostic usage
unassigned
1
0
Colitis
Effects of FK506 on an experimental model of colitis in rats.
causal interaction
unassigned
1
0
Colitis
Activated immunocompetent cells in rat colitis mucosa induced by dextran sulfate sodium and not complete but partial suppression of colitis by FK506.
therapeutic application
unassigned
2
0
Colitis
Transmucosal potential difference in experimental colitis in rats.
ongoing research
therapeutic application
unassigned
4
1
0
Colitis
Reactivation of hapten-induced colitis and its prevention by anti-inflammatory drugs.
causal interaction
unassigned
2
0
Colitis
Attenuation of epithelial injury in acute experimental colitis by immunomodulators.
causal interaction
therapeutic application
unassigned
1
4
0
Colitis
Colonic delivery of dexamethasone from a prodrug accelerates healing of colitis in rats without adrenal suppression.
diagnostic usage
unassigned
4
0
Colitis
A budesonide prodrug accelerates treatment of colitis in rats.
diagnostic usage
unassigned
1
0
Colitis
Topical anticolitic efficacy and selectivity of the glucocorticoid budesonide in a new model of acetic acid-induced acute colitis in the rat.
ongoing research
unassigned
4
0
Colitis
Neutrophil-independence of the initiation of colonic injury. Comparison of results from three models of experimental colitis in the rat.
causal interaction
therapeutic application
unassigned
2
1
0
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