EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
    2.5.1.31 | 0.00004 |
- |
5-benzyl-3-[1-(4-cyclohexylanilino)ethenyl]-4-hydroxy-5,6-dihydropyridin-2(1H)-one |
pH and temperature not specified in the publication, mutant enzyme Y246D |
759096 |
| 2.5.1.31 | 0.00005 |
- |
3-(2-chlorophenyl)-N-(4-isopropylphenyl-5-methylisoxazole-4-carboxamide) |
pH 7.5, 37°C |
739605 |
| 2.5.1.31 | 0.00005 |
- |
7-(azepan-1-yl)-3-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidine |
pH and temperature not specified in the publication, mutant enzyme Y246D |
758567 |
| 2.5.1.31 | 0.00005 |
- |
MAC-0547630 |
pH and temperature not specified in the publication |
758567 |
| 2.5.1.31 | 0.00011 |
- |
N4,N4'-bis(3-(4,5-dihydro-1H-imidazol-2-yl)phenyl)-[1,1'-biphenyl]-4,4'-bicarboxamide |
pH 7.5, 37°C |
738837 |
| 2.5.1.31 | 0.00012 |
- |
N-([1,1'-biphenyl]-4-yl)-4-hydroxy-2-oxo-5-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-3-carboxamide |
pH and temperature not specified in the publication, mutant enzyme Y246D |
759096 |
| 2.5.1.31 | 0.00016 |
- |
N-(4-cyclohexylphenyl)-4-hydroxy-2-oxo-5-(2-phenylethyl)-2,5-dihydro-1H-pyrrole-3-carboxamide |
pH and temperature not specified in the publication, mutant enzyme Y246D |
759096 |
| 2.5.1.31 | 0.00019 |
- |
N-(3-amino-3-oxopropyl)-5-(1-benzothiophen-5-yl)-1-benzyl-N-([4-[(propan-2-yl)oxy]phenyl]methyl)-1H-pyrazole-4-carboxamide |
pH and temperature not specified in the publication, mutant enzyme Y246D |
759596 |
| 2.5.1.31 | 0.00024 |
- |
(2Z)-4-[[3-([1,1'-biphenyl]-3-yl)propyl]amino]-2-hydroxy-4-oxobut-2-enoic acid |
pH and temperature not specified in the publication, mutant enzyme Y246D |
759096 |
| 2.5.1.31 | 0.0003 |
- |
tetramic acid |
pH and temperature not specified in the publication |
721794 |
