EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
1.1.1.42 | 0.000041 |
- |
3-[(6aS,7S,10aR)-2-anilino-9-cyano-7-methyl-8-oxo-6,6a,7,8-tetrahydrobenzo[h]quinazolin-10a(5H)-yl]benzoic acid |
pH and temperature not specified in the publication |
761677 |
1.1.1.42 | 0.000068 |
- |
(+)-ML309 |
inhibition of enzyme mutant IDH1 R132H, pH 7.5, 22°C |
740721 |
1.1.1.42 | 0.000082 |
- |
(6aS,7S,10aR)-7-methyl-8-oxo-10a-phenyl-2-[(pyridin-3-yl)amino]-5,6,6a,7,8,10a-hexahydrobenzo[h]quinazoline-9-carbonitrile |
pH and temperature not specified in the publication |
761677 |
1.1.1.42 | 0.00011 |
- |
(6aS,7S,10aR)-2-anilino-7-methyl-8-oxo-10a-phenyl-5,6,6a,7,8,10a-hexahydrobenzo[h]quinazoline-9-carbonitrile |
pH and temperature not specified in the publication |
761677 |
1.1.1.42 | 0.00012 |
- |
(7R)-1-[(4-fluorophenyl)methyl]-N-[3-[(1R)-1-hydroxyethyl]phenyl]-7-methyl-5-(1H-pyrrole-2-carbonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide |
pH and temperature not specified in the publication |
761677 |
1.1.1.42 | 0.00021 |
- |
(5aS,6S,9aR)-2-benzoyl-6-methyl-7-oxo-9a-phenyl-4,5,5a,6,7,9a-hexahydro-2H-benzo[g]indazole-8-carbonitrile |
pH and temperature not specified in the publication |
761677 |
1.1.1.42 | 0.00027 |
- |
4,5,6,7-tetrabromo-1,3-dihydro-2H-benzimidazol-2-one |
pH and temperature not specified in the publication |
761677 |
1.1.1.42 | 0.00041 |
- |
(6aS,7S,10aR)-7,10a-dimethyl-8-oxo-2-(phenylamino)-5,6,6a,7,8,10a-hexahydrobenzo[h]quinazoline-9-carbonitrile |
pH and temperature not specified in the publication |
761677 |
1.1.1.42 | 0.0015 |
- |
3-[(5aS,6S,9aR)-8-cyano-6-methyl-7-oxo-2,4,5,5a,6,7-hexahydro-9aH-benzo[g]indazol-9a-yl]benzoic acid |
pH and temperature not specified in the publication |
761677 |
1.1.1.42 | 0.00177 |
- |
(6aS,7S,10aR)-2-anilino-7-methyl-8-oxo-10a-phenyl-5,6,6a,7,8,10a-hexahydrobenzo[h]quinazoline-9-carbonitrile |
pH and temperature not specified in the publication |
761677 |