EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor  |
Reference |
|---|
   3.4.22.69 | 0.87 |
- |
ethyl (2E,4S)-4-[[(2R,5S)-2-benzyl-6-methyl-5-[[(5-methylisoxazol-3-yl)carbonyl]amino]-4-oxoheptanoyl]amino]-5-[(3S)-3-methyl-2-oxopyrrolidin-3-yl]pent-2-enoate |
- |
678690 |
| 3.4.22.69 | 0.08 |
- |
ethyl (2E,4S)-4-[[(2R,5S)-5-[(N-tert-butyl-L-seryl)amino]-6-methyl-2-(3-methylbut-2-en-1-yl)-4-oxoheptanoyl]amino]-5-[(3S)-3-methyl-2-oxopyrrolidin-3-yl]pent-2-enoate |
- |
678690 |
| 3.4.22.69 | 0.8 |
- |
ethyl (2E,4S)-4-[[(2R,5S)-6-methyl-2-(3-methylbut-2-en-1-yl)-5-[[(5-methylisoxazol-3-yl)carbonyl]amino]-4-oxoheptanoyl]amino]-5-[(3S)-3-methyl-2-oxopyrrolidin-3-yl]pent-2-enoate |
- |
678690 |
| 3.4.22.69 | 0.00193 |
- |
GC376 |
wild-type, pH 7.5, 25°C |
765793 |
| 3.4.22.69 | 0.00374 |
- |
GC376 |
mutant P108S, pH 7.5, 25°C |
765793 |
| 3.4.22.69 | 0.0026 |
- |
iguesterin |
- |
707696 |
| 3.4.22.69 | 0.007 |
- |
methyl 4-hydroxy-6-(trifluoromethyl)furo[2,3-b]pyridine-2-carboxylate |
- |
679402, 679408 |
| 3.4.22.69 | 0.02 |
- |
ML300 |
pH 7.5, 25°C |
765227 |
| 3.4.22.69 | -999 |
- |
more |
extracts of Rheum palmatum show IC50 values between 0.014 mg/ml and 0.059 mg/ml |
707798 |
| 3.4.22.69 | 0.00022 |
- |
N-(1-benzylpiperidin-4-yl)-2-(N-(4-(tert-butyl)phenyl)vinylsulfonamido)-2-(pyridin-3-yl)acetamide |
pH 7.3, 25°C |
764634 |
