EC Number |
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4.1.1.49 | - |
4.1.1.49 | 1.85 A and 1.7 A resolution structures of the native and pyruvate/Mn2+/phosphate complex, space group of native enzyme is P4(3), space group for enzyme complex is P2(1), unit-cell parameters for native enzyme: a = b = 102.09 A, c = 72.12 A, beta = 90°. Unit-cell parameters for the enzyme complex: a = 56.74 A, b = 55.09 A, c = 90.08 A, beta = 106.17° |
4.1.1.49 | crystals grown by hanging drop vapor diffusion, ADP-ALF3-Mg2+ complex, monoclinic space group C2 with unit cell parameters a : 126.0 A, b : 95.8 A, c : 46.6 A, ADP-ALF3-Mg2+-pyruvate complex, monoclinic space group C2 with unit cell parameters a : 124.7 A, b : 94.2 A, c : 46.3 A |
4.1.1.49 | crystals grown by hanging drop vapor diffusion, monoclinic space group C2, unit cell parameter a = 126.2 A, b = 95.2 A, c = 46.8 A, d = 95.2 A |
4.1.1.49 | hanging drop vapor diffusion method. 2.2 A resolution crystal structure of the enzyme complexed with ATP, Mg2+, Mn2+ and the transition state analogue oxalate. 2.4 A resolution structure of the native enzyme. Unit cell dimensions of the enzyme complex: a = 194.87 A, b = 123.22 A, c = 48.46 A, alpha = beta = gamma = 90°C. Unit cell dimensions of the native enzyme: a = 129.66 A, b = 55.73 A, c = 139.4 A, alpha = 90°, beta = 93.77°, gamma = 90° |
4.1.1.49 | molecular modeling of structure |
4.1.1.49 | oil-microbatch method, the unliganded form crystals belong to space group P2(1)2(1)2(1), with unit-cell parameters a = 64.7, b = 129.91 A, c = 173.39 A. The ATP-liganded crystals are nearly isomorphous to the unliganded crystals. They belong to space group P2(1)2(1)2(1), with unit cell parameters a = 64.07 A, b = 130.55 A, c = 174.2 A |
4.1.1.49 | sitting drop vapour diffusion, primitive orthorhombic crystals, space group P2(1)2(1)2(1), a : 65.97 A, b : 107.61 A, c : 179.08 A |
4.1.1.49 | space group P2(1)2(1)2(1), a : 77.7 A, b : 89.7 A, c 93.8 A |
4.1.1.49 | three-dimensional crystal structure, enzyme possesses a mononucleotide-binding domain unique from other proteins having the P-loop motif |