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EC Number Crystallization (Commentary)
Display the reaction diagram Show all sequences 3.2.1.197in complex with mannose bound in the -1 and +1 subsites. A pair of glutamate residues, Glu227 and Glu268, hydrogen bond to O1 of alpha-mannose, and either of these residues may function as the catalytic base. Conserved lysine residue, Lys199 is a key specificity determinant for beta-1,2-mannosidic linkages
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