EC Number   |
|---|
   3.1.4.39 | ATX alone and in complex with LPAs with different acyl-chain lengths and saturations, X-ray diffraction structure determination and analysis at 1.7-2.0 A resolution |
| 3.1.4.39 | catalytic domain of NPP2 modeled on the known crystal structure of NPP from Xanthomonas axonopodis. Catalytic activity of NPP2 is critically dependent on the presence of a Man8/9GlcNAc2 moiety on Asn-524, a site that is phylogenetically conserved, not only in NPP2 but also in six of seven NPP isozymes. Suggestion that this glycan chain has a structural function and is involved in the interaction between the catalytic and nuclease-like domains of NPP2 |
| 3.1.4.39 | crystal structure determination and analysis of enzyme in complexes with inhibitors 2BoA, 3BoA, and 4BoA, at 1.95 A, 1.90 A, and 1.75 A resolution |
| 3.1.4.39 | enzyme crystal structure analysis, PDB entry 2XR9., overview |
| 3.1.4.39 | purified recombinant ATX alpha isoform, hanging-drop vapour diffusion method, X-ray diffraction structure determination and analysis at 3.0 A resolution |
| 3.1.4.39 | purified recombinant ATX, hanging drop vapour diffusion method, usage of crystallization solution 0.1 M MIB buffer, pH 8, 25% w/v PEG 1500, or 0.1 M MIB buffer, pH 9, 25% w/v PEG 1500, or 0.2 M sodium citrate, 20% w/v PEG 3350, X-ray diffraction structure determination and analysis at 2.0-2.6 A resolution |
| 3.1.4.39 | purified recombinant enzyme, ATX alone and in complex with a small-molecule inhibitor HA155, X-ray diffraction structure determination and analysis at 2.0 A resolution, molecular replacement and single-wavelength anomalous dispersion |
