EC Number   |
|---|
   2.5.1.63 | - |
| 2.5.1.63 | purified enzyme in complex with 5',5'-difluorodeoxy-2-ethynyladenosine and tartrate, X-ray diffraction structure determination and analysis at 1.8 A resolution, molecular replacement using structure with PDB ID 1RQR |
| 2.5.1.63 | purified enzyme in complex with 5'-fluorodeoxy-2-ethynyladenosine, X-ray diffraction structure determination and analysis at 2.4 A resolution, molecular replacement |
| 2.5.1.63 | purified recombinant enzyme, free from tags or bound adenosine, complexed to 2'-deoxy-5'-fluoroadenosine, 4 mg/ml protein is incubated with 20 mM ligand at 25°C for 4 h, followed by crystallization using vapour diffusion against a reservoir containing 30% PEG 1000, 0.1 M phosphate-citrate pH 4.5, 0.2 M Li2SO4, X-ray diffraction structure determination and analysis at 2.4 A resolution, molecular replacement |
| 2.5.1.63 | purified recombinant wild-type and selenomethionine labelled enzyme with bound S-adenosyl-L-methionine, X-ray diffraction structure determination and analysis at 1.9 A resolution, structure modelling of monomers a and b |
| 2.5.1.63 | structure modelling of the fluoride ion/SAM prereaction complex at the active site of the fluorinase immediately prior to SN2 substitution, fluoride ion is modeled into the SAM-fluorinase cocomplex, which is solved by X-ray crystallography, overview |
