EC Number |
Reference |
---|
2.3.1.39 | recombinant purified enzyme, 3 mg/ml protein in 10 mM Tris-HCl, pH 7.4, 1 mM 2-mercaptoethanol, hanging drop vapoir diffusion method, 3 days, room temperature, soaking of crystals in 30% PEG 4000, 100 mM sodium acetate, pH 4.8, 200 mM ammonium acetate, and 20% glycerol for cryoprotection, X-ray diffraction structure determination and analysis at 2.0 A resolution, macromolecular docking simulation with K47A/K190A/R287A/K293A mutant actinorhodin ACP structure, overview |
663400 |
2.3.1.39 | mapping the active site of Escherichia coli malonyl-CoA-acyl carrier protein transacylase by protein crystallography |
671071 |
2.3.1.39 | crystal structure of Mycobacterium tuberculosis MCAT (mtFabD) is determined to 3.0 A resolution by multi-wavelength anomalous dispersion. Phasing is facilitated by Ni2+ ions bound to the 20-residue N-terminal affinity tag, which packed between the two independent copies of mtFabD |
684213 |
2.3.1.39 | crystal structure of MCAT is determined to 2.3 A |
688366 |
2.3.1.39 | crystal structure of HpMCAT at 2.5 A resolution is shown. HpMCAT has a compact folding composed of a large subdomain with a similar core as in alpha/beta hydrolases, and a similar ferredoxin-like small subdomain as in acylphosphatases |
689905 |
2.3.1.39 | to 1.9 A resolution, space group P212121 |
701486 |
2.3.1.39 | 1.2 A resolution |
701546 |
2.3.1.39 | crystal structures of MCAT from Staphylococcus aureus and Streptococcus pneumoniae are determined at 1.46 and 2.1 A resolution, respectively |
719494 |
2.3.1.39 | crystal structures of MCAT from Staphylococcus aureus and Streptococcus pneumoniae are determined at 1.46 and 2.1 A resolution, respectively. In the SaMCAT structure, the N-terminal expression peptide of a neighboring molecule running in the opposite direction of malonyl-CoA makes extensive interactions with the highly conserved Gly-Gln-Gly-Ser-Gln stretch, suggesting a new design platform |
719494 |
2.3.1.39 | the crystal structure of malonyl CoA-acyl carrier protein transacylase (XoMCAT) is determined at 2.3 A resolution in complex with N-cyclohexyl-2-aminoethansulfonic acid |
720468 |