EC Number   |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Reference  |
|---|
   3.4.23.47 | 0.000025 |
- |
VSFNF-PSI[CH2-NH]-PQITL |
pH 5.6, 37°C |
644059 |
| 3.4.23.47 | 0.0006 |
- |
CTLNF-PSI[CH2-NH]-PISP |
pH 5.6, 37°C |
644059 |
| 3.4.23.47 | 0.0002 |
- |
benzyl (S)-1-((2S,3R)-4-((R)-4-(tert-butylcarbamoyl)thiazolidin-3-yl)-3-hydroxy-1-phenylbutan-2-ylamino)-4-amino-1,4-dioxobutan-2-ylcarbamate |
pH 4.7, 37°C, synthetic inhibitor 1 |
644063 |
| 3.4.23.47 | 0.0002 |
- |
N-((S)-1-((2S,3R)-4-((3S,4aS,8aS)-3-(tert-butylcarbamoyl)-octahydroisoquinolin-2(1H)-yl)-3-hydroxy-1-phenylbutan-2-ylamino)-4-amino-1,4-dioxobutan-2-yl)quinoline-3-carboxamide |
pH 4.7, 37°C, synthetic inhibitor 3 |
644063 |
| 3.4.23.47 | 0.0004 |
- |
tert-butyl (2S,3S,5R)-5-(((2S,3R)-3-methyl-1-oxo-1-(phenethylamino)pentan-2-yl)carbamoyl)-1-cyclohexyl-3-hydroxy-6-methylheptan-2-ylcarbamate |
pH 4.7, 37°C, synthetic inhibitor 5 |
644063 |
| 3.4.23.47 | 0.0007 |
- |
(2R,4S,5S)-6-cyclohexyl-5-(3,3-dimethylbutanamido)-4-hydroxy-2-isopropyl-N-((2S,3R)-3-methyl-1-oxo-1-(phenethylamino)pentan-2-yl)hexanamide |
pH 4.7, 37°C, synthetic inhibitor 4 |
644063 |
| 3.4.23.47 | 0.0000012 |
- |
(hydroxyethyl)amide isostere |
- |
665102 |
| 3.4.23.47 | 0.000005 |
- |
acetyl-pepstatin |
pH 4.7, competitive versus YVSQNFPIVQNR |
665102 |
| 3.4.23.47 | 0.000015 |
- |
pepstatin A |
pH 4.7 |
665102 |
| 3.4.23.47 | 0.00000016 |
- |
TMC-126 |
- |
679179 |
