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EC Number	Temperature Stability Minimum [�C]	Temperature Stability Maximum [�C]	Commentary	Reference
2.1.2.3	10	40	the enzyme retains stable at 10-40°C with more than 80% activity remaining after 1 h incubation	756701
2.1.2.3	42.1	-	three transitions at a Tm of 42.1°C, 44.7°C and 46.9°C	756701
2.1.2.3	44.7	-	three transitions at a Tm of 42.1°C, 44.7°C and 46.9°C	756701
2.1.2.3	45	-	10 min, the bifunctional AICAR transformylase/IMP cyclohydrolase (ATIC) is stable at lower temperatures and both the activities start declining after 45°C	756701
2.1.2.3	46.9	-	three transitions at a Tm of 42.1°C, 44.7°C and 46.9°C	756701

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Release 2023.1 (January 2023)