EC Number |
Subunits |
Reference |
---|
2.7.7.7 | ? |
- |
643589, 643608, 643609 |
2.7.7.7 | ? |
DNA polymerase alpha is composed of: 1. a cluster of related high-molecular-weight polypeptides predominantly of 165000-180000 MW containing the catalytic function, 2. a polypeptide of 70000 MW with unknown catalytic function, 3. two polypeptides of 55000-60000 and 48000-49000 associated with primase activity |
643589 |
2.7.7.7 | ? |
x * 101224, calculated from sequence |
-, 720565 |
2.7.7.7 | ? |
x * 125000 + x * 55000, polymerase delta |
643608 |
2.7.7.7 | ? |
x * 130000, SDS-PAGE |
721774 |
2.7.7.7 | ? |
x * 140000 (alpha) + x * 25000 (epsilon) + x * 10000 (theta), pol III, can repair short gaps created by nuclease in duplex DNA, for efficient replication of the long, single-stranded templates pol III requires auxiliary subunits beta MW 37000, gamma MW 52000, and delta MW 32000 |
643592 |
2.7.7.7 | ? |
x * 140000 (alpha) + x * 37000 (beta) + x * 52000 (gamma) + x * 32000 (delta) + x * 25000 (epsilon) + x * 10000 (theta) + x * 78000 (tau) |
643609 |
2.7.7.7 | ? |
x * 140000, catalytic subunit, + 55000, accessory subunit, SDS-PAGE |
723108 |
2.7.7.7 | ? |
x * 180000 + x * 86000 + x * 58000 + x * 48000, polymerase alpha |
643608 |
2.7.7.7 | ? |
x * 182000 (alpha) + x * 60000 (beta) + x * 50000 (gamma), core polymerase |
643609 |