EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.1.11.6 | duplex DNA containing single-stranded termini + H2O |
- |
Escherichia coli |
hydrolyzed single-stranded DNA |
- |
? |
3.1.11.6 | more |
involved in methyl-directed mismatch repair |
Escherichia coli |
? |
- |
? |
3.1.11.6 | more |
RecBCD subunit RecD is required for initiation of homologous recombination in Escherichia coli and essential for phage lambda recombination, in contrast to exonuclease RecJ, overview |
Escherichia coli |
? |
- |
? |
3.1.11.6 | more |
ExoVII is refractory to mutation, inactivation appears to be lethal. ExoVII appears to be essential for growth of Haemophilus influenzae, possibly, given its ability to process DNA flaps, indicating a requirement for the activities of this protein in replicative DNA synthesis |
Haemophilus influenzae |
? |
- |
? |
3.1.11.6 | more |
mutants lacking ExoVII are viable during all phases of the bacterial life cycle, but cannot compete with wild-type cells during long-term stationary phase incubation. Mutants lacking ExoVII are defective in DNA catabolism |
Escherichia coli K-12 |
? |
- |
? |
3.1.11.6 | more |
active site motif with two conserved aspartate residues in the large (XseA/TM1768) subunit. Residues Asp235 and Asp240 are essential for the nuclease activity |
Thermotoga maritima |
? |
- |
? |
3.1.11.6 | more |
no significant activity on dsDNA. Active site motif with two conserved aspartate residues in the large (XseA/TM1768) subunit. Residues Asp235 and Asp240 are essential for the nuclease activity |
Thermotoga maritima |
? |
- |
? |
3.1.11.6 | more |
exonuclease VII can digest ssDNA from 3' ends |
Escherichia coli |
? |
- |
? |
3.1.11.6 | more |
exonuclease VII cleaves msDNA, e.g. Ec78 and Ec83 |
Escherichia coli |
? |
- |
? |
3.1.11.6 | more |
mutants lacking ExoVII are viable during all phases of the bacterial life cycle, but cannot compete with wild-type cells during long-term stationary phase incubation. Mutants lacking ExoVII are defective in DNA catabolism |
Escherichia coli K-12 ZK126 |
? |
- |
? |